- Stress tolerance to stress escape in plants: role of the OXS2 zinc-finger transcription factor family
[作者：Blanvillain, R; Wei, S; Wei, PC; Kim, JH; Ow, DW,期刊：EMBO journal, 页码：3812-3822 , 文章类型： Article，,卷期：2011年30-18]
- During dire conditions, the channelling of resources into reproduction ensures species preservation. This strategy of survival through the next generation is particularly important for plants that are unable to escape th...
- FBF represses the Cip/Kip cell-cycle inhibitor CKI-2 to promote self-renewal of germline stem cells in C. elegans
[作者：Kalchhauser, I; Farley, BM; Pauli, S; Ryder, SP; Ciosk, R,期刊：EMBO journal, 页码：3823-3829 , 文章类型： Article，,卷期：2011年30-18]
- Although the decision between stem cell self-renewal and differentiation has been linked to cell-cycle modifications, our understanding of cell-cycle regulation in stem cells is very limited. Here, we report that FBF/Pum...
- Bidirectional integrative regulation of Cav1.2 calcium channel by microRNA miR-103: role in pain
[作者：Favereaux, A; Thoumine, O; Bouali-Benazzouz, R; Roques, V; Papon, MA; Salam, SA; Drutel, G; Leger, C; Calas, A; Nagy, F; Landry, M,期刊：EMBO journal, 页码：3830-3841 , 文章类型： Article，,卷期：2011年30-18]
- Chronic pain states are characterized by long-term sensitization of spinal cord neurons that relay nociceptive information to the brain. Among the mechanisms involved, up-regulation of Cav1.2-comprising L-type calcium ch...
- Regulation of glycine receptor diffusion properties and gephyrin interactions by protein kinase C
[作者：Specht, CG; Grunewald, N; Pascual, O; Rostgaard, N; Schwarz, G; Triller, A,期刊：EMBO journal, 页码：3842-3853 , 文章类型： Article，,卷期：2011年30-18]
- Glycine receptors (GlyRs) can dynamically exchange between synaptic and extrasynaptic locations through lateral diffusion within the plasma membrane. Their accumulation at inhibitory synapses depends on the interaction o...
- 4.4 angstrom cryo-EM structure of an enveloped alphavirus Venezuelan equine encephalitis virus
[作者：Zhang, R; Hryc, CF; Cong, Y; Liu, XG; Jakana, J; Gorchakov, R; Baker, ML; Weaver, SC; Chiu, W,期刊：EMBO journal, 页码：3854-3863 , 文章类型： Article，,卷期：2011年30-18]
- Venezuelan equine encephalitis virus (VEEV), a member of the membrane-containing Alphavirus genus, is a human and equine pathogen, and has been developed as a biological weapon. Using electron cryo-microscopy (cryo-EM), ...
- Crystal structure of the Haemophilus influenzae Hap adhesin reveals an intercellular oligomerization mechanism for bacterial aggregation
[作者：Meng, GY; Spahich, N; Kenjale, R; Waksman, G; St Geme, JW,期刊：EMBO journal, 页码：3864-3874 , 文章类型： Article，,卷期：2011年30-18]
- Bacterial biofilms are complex microbial communities that are common in nature and are being recognized increasingly as an important determinant of bacterial virulence. However, the structural determinants of bacterial a...
- C/EBP beta: lost beyond translation
[作者：Peeper, DS,期刊：EMBO journal, 页码：3663-3664 , 文章类型： Editorial Material，,卷期：2011年30-18]
- A/U-rich elements (AREs) are short sequences in the 3'UTRs of genes, acting in cis to regulate mRNA decay and translation. In this issue of The EMBO Journal, Basu et al (2011) describe a new function for AREs, in the con...
- Off-track takes Frizzled off the canonical path
[作者：Vincent, JP; Beckett, K,期刊：EMBO journal, 页码：3665-3666 , 文章类型： Editorial Material，,卷期：2011年30-18]
- Like many other signalling pathways, the Wnt pathway is seen as part of a network that integrates extracellular information mediated by a variety of cell surface proteins to produce cell context-specific outputs. The ide...
- Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases
[作者：Strasser, A; Cory, S; Adams, JM,期刊：EMBO journal, 页码：3667-3683 , 文章类型： Review，,卷期：2011年30-18]
- Apoptosis, the major form of programmed cell death in metazoan organisms, plays critical roles in normal development, tissue homeostasis and immunity, and its disturbed regulation contributes to many pathological states,...
- ERK7 is a negative regulator of protein secretion in response to amino-acid starvation by modulating Sec16 membrane association
[作者：Zacharogianni, M; Kondylis, V; Tang, Y; Farhan, H; Xanthakis, D; Fuchs, F; Boutros, M; Rabouille, C,期刊：EMBO journal, 页码：3684-3700 , 文章类型： Article，,卷期：2011年30-18]
- RNAi screening for kinases regulating the functional organization of the early secretory pathway in Drosophila S2 cells has identified the atypical Mitotic-Associated Protein Kinase (MAPK) Extracellularly regulated kinas...
- A Drosophila metallophosphoesterase mediates deglycosylation of rhodopsin
[作者：Cao, JG; Li, Y; Xia, WJ; Reddig, K; Hu, W; Xie, W; Li, HS; Han, JH,期刊：EMBO journal, 页码：3701-3713 , 文章类型： Article，,卷期：2011年30-18]
- Oligosaccharide chains of newly synthesized membrane receptors are trimmed and modified to optimize their trafficking and/or signalling before delivery to the cell surface. For most membrane receptors, the functional sig...
- 3 ' UTR elements inhibit Ras-induced C/EBP beta post-translational activation and senescence in tumour cells
[作者：Basu, SK; Malik, R; Huggins, CJ; Lee, S; Sebastian, T; Sakchaisri, K; Quinones, OA; Alvord, WG; Johnson, PF,期刊：EMBO journal, 页码：3714-3728 , 文章类型： Article，,卷期：2011年30-18]
- C/EBP beta is an auto-repressed protein that becomes post-translationally activated by Ras-MEK-ERK signalling. C/EBP beta is required for oncogene-induced senescence (OIS) of primary fibroblasts, but also displays pro-on...
- PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling
[作者：Peradziryi, H; Kaplan, NA; Podleschny, M; Liu, XP; Wehner, P; Borchers, A; Tolwinski, NS,期刊：EMBO journal, 页码：3729-3740 , 文章类型： Article，,卷期：2011年30-18]
- Wnt signalling is an evolutionarily conserved pathway that directs cell-fate determination and morphogenesis during metazoan development. Wnt ligands are secreted glycoproteins that act at a distance causing a wide range...
- Egr-1 decreases adipocyte insulin sensitivity by tilting PI3K/Akt and MAPK signal balance in mice
[作者：Yu, X; Shen, N; Zhang, ML; Pan, FY; Wang, C; Jia, WP; Liu, C; Gao, Q; Gao, X; Xue, B; Li, CJ,期刊：EMBO journal, 页码：3754-3765 , 文章类型： Article，,卷期：2011年30-18]
- It is well known that insulin can activate both PI3K/Akt pathway, which is responsible for glucose uptake, and MAPK pathway, which is crucial for insulin resistance formation. But, it is unclear exactly how the two pathw...
- A new basal promoter element recognized by RNA polymerase core enzyme
[作者：Yuzenkova, Y; Tadigotla, VR; Severinov, K; Zenkin, N,期刊：EMBO journal, 页码：3766-3775 , 文章类型： Article，,卷期：2011年30-18]
- Bacterial promoters are recognized by RNA polymerase (RNAP) sigma subunit, which specifically interacts with the -10 and -35 promoter elements. Here, we provide evidence that the beta' zipper, an evolutionarily conserved...
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