- TFEBulous control of traffic by mTOR
[作者：Jacinto, E,期刊：EMBO journal, 页码：3215-3216 , 文章类型： Editorial Material，,卷期：2011年30-16]
- Cell growth is accompanied by the synthesis of macromolecules and biogenesis of organelles. The protein kinase mTOR (mechanistic or mammalian target of rapamycin) controls these processes by sensing availability of growt...
- Regulation of TFEB and V-ATPases by mTORC1
[作者：Pena-Llopis, S; Vega-Rubin-de-Celis, S; Schwartz, JC; Wolff, NC; Tran, TAT; Zou, LH; Xie, XJ; Corey, DR; Brugarolas, J,期刊：EMBO journal, 页码：3242-3258 , 文章类型： Article，,卷期：2011年30-16]
- Mammalian target of rapamycin (mTOR) complex 1 (mTORC1) is an important, highly conserved, regulator of cell growth. Ancient among the signals that regulate mTORC1 are nutrients. Amino acids direct mTORC1 to the surface ...
- Nedd4-1 binds and ubiquitylates activated FGFR1 to control its endocytosis and function
[作者：Persaud, A; Alberts, P; Hayes, M; Guettler, S; Clarke, I; Sicheri, F; Dirks, P; Ciruna, B; Rotin, D,期刊：EMBO journal, 页码：3259-3273 , 文章类型： Article，,卷期：2011年30-16]
- Fibroblast growth factor receptor 1 (FGFR1) has critical roles in cellular proliferation and differentiation during animal development and adult homeostasis. Here, we show that human Nedd4 (Nedd4-1), an E3 ubiquitin liga...
- Control of Ubp3 ubiquitin protease activity by the Hog1 SAPK modulates transcription upon osmostress
[作者：Sole, C; Nadal-Ribelles, M; Kraft, C; Peter, M; Posas, F; de Nadal, E,期刊：EMBO journal, 页码：3274-3284 , 文章类型： Article，,卷期：2011年30-16]
- Protein ubiquitylation is a key process in the regulation of many cellular processes. The balance between the activity of ubiquitin ligases and that of proteases controls the level of ubiquitylation. In response to extra...
- Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex
[作者：Bentley, ML; Corn, JE; Dong, KC; Phung, Q; Cheung, TK; Cochran, AG,期刊：EMBO journal, 页码：3285-3297 , 文章类型： Article，,卷期：2011年30-16]
- The Polycomb repressive complex 1 (PRC1) mediates gene silencing, in part by monoubiquitination of histone H2A on lysine 119 (uH2A). Bmi1 and Ring1b are critical components of PRC1 that heterodimerize via their N-termina...
- Tdrd1 acts as a molecular scaffold for Piwi proteins and piRNA targets in zebrafish
[作者：Huang, HY; Houwing, S; Kaaij, LJT; Meppelink, A; Redl, S; Gauci, S; Vos, H; Draper, BW; Moens, CB; Burgering, BM; Ladurner, P; Krijgsveld, J; Berezikov, E; Ketting, RF,期刊：EMBO journal, 页码：3298-3308 , 文章类型： Article，,卷期：2011年30-16]
- Piwi proteins function in an RNAi-like pathway that silences transposons. Piwi-associated RNAs, also known as piRNAs, act as a guide to identify Piwi targets. The tudor domain-containing protein Tdrd1 has been linked to ...
- Developmental regulation of CYCA2s contributes to tissue-specific proliferation in Arabidopsis
[作者：Vanneste, S; Coppens, F; Lee, E; Donner, TJ; Xie, ZD; Van Isterdael, G; Dhondt, S; De Winter, F; De Rybel, B; Vuylsteke, M; De Veylder, L; Friml, J; Inze, D; Grotewold, E; Scarpella, E; Sack, F; Beemster, GTS; Beeckman, T,期刊：EMBO journal, 页码：3430-3441 , 文章类型： Article，,卷期：2011年30-16]
- In multicellular organisms, morphogenesis relies on a strict coordination in time and space of cell proliferation and differentiation. In contrast to animals, plant development displays continuous organ formation and ada...
- Distinct pathways for modification of the bacterial cell wall by non-canonical D-amino acids
[作者：Cava, F; de Pedro, MA; Lam, H; Davis, BM; Waldor, MK,期刊：EMBO journal, 页码：3442-3453 , 文章类型： Article，,卷期：2011年30-16]
- Production of non-canonical D-amino acids (NCDAAs) in stationary phase promotes remodelling of peptidoglycan (PG), the polymer that comprises the bacterial cell wall. Impairment of NCDAAs production leads to excessive ac...
- PICH and BLM limit histone association with anaphase centromeric DNA threads and promote their resolution
[作者：Ke, YW; Huh, JW; Warrington, R; Li, B; Wu, N; Leng, M; Zhang, JM; Ball, HL; Li, B; Yu, HT,期刊：EMBO journal, 页码：3309-3321 , 文章类型： Article，,卷期：2011年30-16]
- Centromeres nucleate the formation of kinetochores and are vital for chromosome segregation during mitosis. The SNF2 family helicase PICH (Plk1-interacting checkpoint helicase) and the BLM (the Bloom's syndrome protein) ...
- Probing the in vivo function of Mad1:C-Mad2 in the spindle assembly checkpoint
[作者：Fava, LL; Kaulich, M; Nigg, EA; Santamaria, A,期刊：EMBO journal, 页码：3322-3336 , 文章类型： Article，,卷期：2011年30-16]
- The spindle assembly checkpoint (SAC) restrains anaphase until all chromosomes become bi-oriented on the mitotic spindle. The SAC protein Mad2 can fold into two distinct conformers, open (O) and closed (C), and can asymm...
- Targeting of Nbp1 to the inner nuclear membrane is essential for spindle pole body duplication
[作者：Kupke, T; Di Cecco, L; Muller, HM; Neuner, A; Adolf, F; Wieland, F; Nickel, W; Schiebel, E,期刊：EMBO journal, 页码：3337-3352 , 文章类型： Article，,卷期：2011年30-16]
- Spindle pole bodies (SPBs), like nuclear pore complexes, are embedded in the nuclear envelope (NE) at sites of fusion of the inner and outer nuclear membranes. A network of interacting proteins is required to insert a cy...
- Global analysis of core histones reveals nucleosomal surfaces required for chromosome bi-orientation
[作者：Kawashima, S; Nakabayashi, Y; Matsubara, K; Sano, N; Enomoto, T; Tanaka, K; Seki, M; Horikoshi, M,期刊：EMBO journal, 页码：3353-3367 , 文章类型： Article，,卷期：2011年30-16]
- The attachment of sister kinetochores to microtubules from opposite spindle poles is essential for faithful chromosome segregation. Kinetochore assembly requires centromere-specific nucleosomes containing the histone H3 ...
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