- Micro-balancing innate immunity to Salmonella
[作者：Voinnet, O,期刊：EMBO journal, 页码：1877-1879 , 文章类型： Editorial Material，,卷期：2011年30-10]
- MicroRNAs are 19-24 nt-long RNAs that post-transcriptionally regulate eukaryotic gene expression. Beside their important roles in patterning and development, miRNAs also orchestrate responses to pathogen infections. In t...
- Is PrP the road to ruin?
[作者：Barton, KA; Caughey, B,期刊：EMBO journal, 页码：1882-1884 , 文章类型： Editorial Material，,卷期：2011年30-10]
- Neurodegenerative disorders are one among the most debilitating diseases of an ageing population. Understanding the mechanisms of neuronal cell death during pathogenesis of diseases such as Alzheimer's, Parkinson's, Hunt...
- Chromatin: constructing the big picture
[作者：van Steensel, B,期刊：EMBO journal, 页码：1885-1895 , 文章类型： Review，,卷期：2011年30-10]
- Chromatin is the ensemble of genomic DNA and a large number of proteins. Various genome-wide mapping techniques have begun to reveal that, despite the tremendous complexity, chromatin organization is governed by simple p...
- Control of mammary myoepithelial cell contractile function by alpha 3 beta 1 integrin signalling
[作者：Raymond, K; Cagnet, S; Kreft, M; Janssen, H; Sonnenberg, A; Glukhova, MA,期刊：EMBO journal, 页码：1896-1906 , 文章类型： Article，,卷期：2011年30-10]
- In the functionally differentiated mammary gland, basal myoepithelial cells contract to eject the milk produced by luminal epithelial cells from the body. We report that conditional deletion of a laminin receptor, alpha ...
- Crystal structure of the intraflagellar transport complex 25/27
[作者：Bhogaraju, S; Taschner, M; Morawetz, M; Basquin, C; Lorentzen, E,期刊：EMBO journal, 页码：1907-1918 , 文章类型： Article，,卷期：2011年30-10]
- The cilium is an important organelle that is found on many eukaryotic cells, where it serves essential functions in motility, sensory reception and signalling. Intraflagellar transport (IFT) is a vital process for the fo...
- The SWI/SNF complex acts to constrain distribution of the centromeric histone variant Cse4
[作者：Gkikopoulos, T; Singh, V; Tsui, K; Awad, S; Renshaw, MJ; Scholfield, P; Barton, GJ; Nislow, C; Tanaka, TU; Owen-Hughes, T,期刊：EMBO journal, 页码：1919-1927 , 文章类型： Article，,卷期：2011年30-10]
- In order to gain insight into the function of the Saccharomyces cerevisiae SWI/SNF complex, we have identified DNA sequences to which it is bound genomewide. One surprising observation is that the complex is enriched at ...
- Integrative epigenomic mapping defines four main chromatin states in Arabidopsis
[作者：Roudier, F; Ahmed, I; Berard, C; Sarazin, A; Mary-Huard, T; Cortijo, S; Bouyer, D; Caillieux, E; Duvernois-Berthet, E; Al-Shikhley, L; Giraut, L; Despres, B; Drevensek, S; Barneche, F; Derozier, S; Brunaud, V; Aubourg, S; Schnittger, A; Bowler, C; Martin-Magniette, ML; Robin, S; Caboche, M; Colot, V,期刊：EMBO journal, 页码：1928-1938 , 文章类型： Article，,卷期：2011年30-10]
- Post-translational modification of histones and DNA methylation are important components of chromatin-level control of genome activity in eukaryotes. However, principles governing the combinatorial association of chromat...
- The CW domain, a new histone recognition module in chromatin proteins
[作者：Hoppmann, V; Thorstensen, T; Kristiansen, PE; Veiseth, SV; Rahman, MA; Finne, K; Aalen, RB; Aasland, R,期刊：EMBO journal, 页码：1939-1952 , 文章类型： Article，,卷期：2011年30-10]
- Post-translational modifications of the N-terminal histone tails, including lysine methylation, have key roles in regulation of chromatin and gene expression. A number of protein modules have been identified that recogni...
- A novel assay identifies transcript elongation roles for the Nup84 complex and RNA processing factors
[作者：Tous, C; Rondon, AG; Garcia-Rubio, M; Gonzalez-Aguilera, C; Luna, R; Aguilera, A,期刊：EMBO journal, 页码：1953-1964 , 文章类型： Article，,卷期：2011年30-10]
- To clarify the role of a number of mRNA processing factors in transcription elongation, we developed an in vivo assay for direct analysis of elongation on chromatin. The assay relies on two substrates containing two G-le...
- RNA-Seq analysis in mutant zebrafish reveals role of U1C protein in alternative splicing regulation
[作者：Rosel, TD; Hung, LH; Medenbach, J; Donde, K; Starke, S; Benes, V; Ratsch, G; Bindereif, A,期刊：EMBO journal, 页码：1965-1976 , 文章类型： Article，,卷期：2011年30-10]
- Precise 5' splice-site recognition is essential for both constitutive and regulated pre-mRNA splicing. The U1 small nuclear ribonucleoprotein particle (snRNP)-specific protein U1C is involved in this first step of splice...
- Analysis of the host microRNA response to Salmonella uncovers the control of major cytokines by the let-7 family
[作者：Schulte, LN; Eulalio, A; Mollenkopf, HJ; Reinhardt, R; Vogel, J,期刊：EMBO journal, 页码：1977-1989 , 文章类型： Article，,卷期：2011年30-10]
- MicroRNAs have well-established roles in eukaryotic host responses to viruses and extracellular bacterial pathogens. In contrast, microRNA responses to invasive bacteria have remained unknown. Here, we report cell type-d...
- microRNA-214 contributes to melanoma tumour progression through suppression of TFAP2C
[作者：Penna, E; Orso, F; Cimino, D; Tenaglia, E; Lembo, A; Quaglino, E; Poliseno, L; Haimovic, A; Osella-Abate, S; De Pitta, C; Pinatel, E; Stadler, MB; Provero, P; Bernengo, MG; Osman, I; Taverna, D,期刊：EMBO journal, 页码：1990-2007 , 文章类型： Article，,卷期：2011年30-10]
- Malignant melanoma is fatal in its metastatic stage. It is therefore essential to unravel the molecular mechanisms that govern disease progression to metastasis. MicroRNAs (miRs) are endogenous non-coding RNAs involved i...
- Sld7, an Sld3-associated protein required for efficient chromosomal DNA replication in budding yeast
[作者：Tanaka, T; Umemori, T; Endo, S; Muramatsu, S; Kanemaki, M; Kamimura, Y; Obuse, C; Araki, H,期刊：EMBO journal, 页码：2019-2030 , 文章类型： Article，,卷期：2011年30-10]
- Genetic screening of yeast for sld (synthetic lethality with dpb11) mutations has identified replication proteins, including Sld2, -3, and -5, and clarified the molecular mechanisms underlying eukaryotic chromosomal DNA ...
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