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  • Competition Among Stem Cells Gets Sticky
    [作者:Wu, DC; Johnston, LA,期刊:Cell Stem Cell, 页码:459-460 , 文章类型: Editorial Material,,卷期:2009年5-5]
  • In a recent report in Science, Issigonis et al. (2009) demonstrate that an inhibitor of JAK-STAT signaling controls integrin-mediated niche adhesion in the Drosophila testis, thereby limiting competition between germline...
  • FoxO3 Regulates Neural Stem Cell Homeostasis
    [作者:Renault, VM; Rafalski, VA; Morgan, AA; Salih, DAM; Brett, JO; Webb, AE; Villeda, SA; Thekkat, PU; Guillerey, C; Denko, NC; Palmer, TD; Bufte, AJ; Brunet, A,期刊:Cell Stem Cell, 页码:527-539 , 文章类型: Article,,卷期:2009年5-5]
  • In the nervous system, neural stem cells (NSCs) are necessary for the generation of new neurons and for cognitive function. Here we show that FoxO3, a member of a transcription factor family known to extend lifespan in i...
  • FoxOs Cooperatively Regulate Diverse Pathways Governing Neural Stem Cell Homeostasis
    [作者:Paik, JH; Ding, ZH; Narurkar, R; Ramkissoon, S; Muller, F; Kamoun, WS; Chae, SS; Zheng, HW; Ying, HQ; Mahoney, J; Hiller, D; Jiang, S; Protopopov, A; Wong, WH; Chin, L; Ligon, KL; DePinho, RA,期刊:Cell Stem Cell, 页码:540-553 , 文章类型: Article,,卷期:2009年5-5]
  • The PI3K-AKT-FoxO pathway is integral to lifespan regulation in lower organisms and essential for the stability of long-lived cells in mammals. Here, we report the impact of combined FoxO1, 3, and 4 deficiencies on mamma...
  • A Robust and Highly Efficient Immune Cell Reprogramming System
    [作者:Bussmann, LH; Schubert, A; Manh, TPV; De Andres, L; Desbordes, SC; Parra, M; Zimmermann, T; Rapino, F; Rodriguez-Ubreva, J; Ballestar, E; Graf, T,期刊:Cell Stem Cell, 页码:554-566 , 文章类型: Article,,卷期:2009年5-5]
  • Here we describe a lineage reprogramming system consisting of a B cell line with an estradiol-inducible form of C/EBP alpha where cells can be converted into macrophage-like cells at 100% efficiency within 2 to 3 days. T...
  • The Tortoise, the Hare, and the FoxO
    [作者:Chen, E; Finkel, T,期刊:Cell Stem Cell, 页码:451-452 , 文章类型: Editorial Material,,卷期:2009年5-5]
  • Maintaining stem cell quiescence is intimately connected to preserving long-term self-renewal potential. In this issue of Cell Stem Cell, Paik et al. (2009) and Renault et al. (2009) demonstrate a role for FoxO transcrip...
  • Mutant CEBPA: Priming Stem Cells for Myeloid Leukemogenesis
    [作者:Somervaille, TCP; Cleary, ML,期刊:Cell Stem Cell, 页码:453-454 , 文章类型: Editorial Material,,卷期:2009年5-5]
  • In a recent study published in Cancer Cell, Bereshchenko and colleagues (2009) report a knockin mouse model that represents the most frequently occurring biallelic combination of CEBPA mutations found in human acute myel...