- Competition Among Stem Cells Gets Sticky
[作者:Wu, DC; Johnston, LA,期刊:Cell Stem Cell, 页码:459-460 , 文章类型: Editorial Material,,卷期:2009年5-5]
- In a recent report in Science, Issigonis et al. (2009) demonstrate that an inhibitor of JAK-STAT signaling controls integrin-mediated niche adhesion in the Drosophila testis, thereby limiting competition between germline...
- Fighting Fat with Fat: The Expanding Field of Adipose Stem Cells
[作者:Zeve, D; Tang, W; Graff, J,期刊:Cell Stem Cell, 页码:472-481 , 文章类型: Review,,卷期:2009年5-5]
- We are in the midst of a dire, unprecedented, and global epidemic of obesity and secondary sequelae, most prominently diabetes and hyperlipidemia. Underlying this epidemic is the most hated of cells, adipocytes, and thei...
- HLA-Matching Potential of an Established Human Embryonic Stem Cell Bank in China
[作者:Lin, G; Xie, YB; OuYang, Q; Qian, XB; Xie, PY; Zhou, XY; Xiong, B; Tan, YQ; Li, W; Deng, LY; Zhou, J; Zhou, D; Du, LL; Cheng, DH; Liao, Y; Gu, YF; Zhang, SP; Liu, TC; Sun, Y; Lu, GX,期刊:Cell Stem Cell, 页码:461-465 , 文章类型: Article,,卷期:2009年5-5]
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- A Small-Molecule Inhibitor of Tgf-beta Signaling Replaces Sox2 in Reprogramming by Inducing Nanog
[作者:Ichida, JK; Blanchard, J; Lam, K; Son, EY; Chung, JE; Egli, D; Loh, KM; Carter, AC; Di Giorgio, FP; Koszka, K; Huangfu, DW; Akutsu, H; Liu, DR; Rubin, LL; Eggan, K,期刊:Cell Stem Cell, 页码:491-503 , 文章类型: Article,,卷期:2009年5-5]
- The combined activity of three transcription factors can reprogram adult cells into induced pluripotent stem cells (iPSCs). However, the transgenic methods used for delivering reprogramming factors have raised concerns r...
- Autocrine TGF-beta Signaling Maintains Tumorigenicity of Glioma-Initiating Cells through Sry-Related HMG-Box Factors
[作者:Ikushima, H; Todo, T; Ino, Y; Takahashi, M; Miyazawa, K; Miyazono, K,期刊:Cell Stem Cell, 页码:504-514 , 文章类型: Article,,卷期:2009年5-5]
- Despite aggressive surgery, radiotherapy, and chemotherapy, treatment of malignant glioma remains formidable. Although the concept of cancer stem cells reveals a new framework of cancer therapeutic strategies against mal...
- FoxO3 Regulates Neural Stem Cell Homeostasis
[作者:Renault, VM; Rafalski, VA; Morgan, AA; Salih, DAM; Brett, JO; Webb, AE; Villeda, SA; Thekkat, PU; Guillerey, C; Denko, NC; Palmer, TD; Bufte, AJ; Brunet, A,期刊:Cell Stem Cell, 页码:527-539 , 文章类型: Article,,卷期:2009年5-5]
- In the nervous system, neural stem cells (NSCs) are necessary for the generation of new neurons and for cognitive function. Here we show that FoxO3, a member of a transcription factor family known to extend lifespan in i...
- FoxOs Cooperatively Regulate Diverse Pathways Governing Neural Stem Cell Homeostasis
[作者:Paik, JH; Ding, ZH; Narurkar, R; Ramkissoon, S; Muller, F; Kamoun, WS; Chae, SS; Zheng, HW; Ying, HQ; Mahoney, J; Hiller, D; Jiang, S; Protopopov, A; Wong, WH; Chin, L; Ligon, KL; DePinho, RA,期刊:Cell Stem Cell, 页码:540-553 , 文章类型: Article,,卷期:2009年5-5]
- The PI3K-AKT-FoxO pathway is integral to lifespan regulation in lower organisms and essential for the stability of long-lived cells in mammals. Here, we report the impact of combined FoxO1, 3, and 4 deficiencies on mamma...
- A Robust and Highly Efficient Immune Cell Reprogramming System
[作者:Bussmann, LH; Schubert, A; Manh, TPV; De Andres, L; Desbordes, SC; Parra, M; Zimmermann, T; Rapino, F; Rodriguez-Ubreva, J; Ballestar, E; Graf, T,期刊:Cell Stem Cell, 页码:554-566 , 文章类型: Article,,卷期:2009年5-5]
- Here we describe a lineage reprogramming system consisting of a B cell line with an estradiol-inducible form of C/EBP alpha where cells can be converted into macrophage-like cells at 100% efficiency within 2 to 3 days. T...
- The Tortoise, the Hare, and the FoxO
[作者:Chen, E; Finkel, T,期刊:Cell Stem Cell, 页码:451-452 , 文章类型: Editorial Material,,卷期:2009年5-5]
- Maintaining stem cell quiescence is intimately connected to preserving long-term self-renewal potential. In this issue of Cell Stem Cell, Paik et al. (2009) and Renault et al. (2009) demonstrate a role for FoxO transcrip...
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