- Parental Reporting of Adverse Drug Reactions Associated with Attention-Deficit Hyperactivity Disorder (ADHD) Medications in Children Attending Specialist Paediatric Clinics in the UK
[作者:Tobaiqy, M; Stewart, D; Helms, PJ; Williams, J; Crum, J; Steer, C; McLay, J,期刊:Drug safety, 页码:211-219 , 文章类型: Article,,卷期:2011年34-3]
- Background: The development of systems to ensure appropriate and informed use of medicines in children is a global priority. Current pharmacovigilance systems, such as the UK Yellow Card Scheme, are limited by opportunis...
- Intensive Monitoring of Pregabalin Results from an Observational, Web-Based, Prospective Cohort Study in the Netherlands Using Patients as a Source of Information
[作者:Harinark, L; van Puijenbroek, E; Straus, S; van Grootheest, K,期刊:Drug safety, 页码:221-231 , 文章类型: Article,,卷期:2011年34-3]
- Background: Pregabalin is one of the first drugs registered for the treatment of neuropathic pain. It is also indicated as adjuvant therapy in the treatment of epilepsy and for generalized anxiety disorder. Pregabalin is...
- Evaluation of Drug-Induced Serious Hepatotoxicity (eDISH) Application of this Data Organization Approach to Phase III Clinical Trials of Rivaroxaban after Total Hip or Knee Replacement Surgery
[作者:Watkins, PB; Desai, M; Berkowitz, SD; Peters, G; Horsmans, Y; Larrey, D; Maddrey, W,期刊:Drug safety, 页码:243-252 , 文章类型: Article,,卷期:2011年34-3]
- Background: The most specific indicator of a drug-induced liver injury signal in a clinical trial database is believed to be the occurrence of subjects experiencing drug-associated elevations in both serum ALT and serum ...
- Reporting Patterns Indicative of Adverse Drug Interactions A Systematic Evaluation in VigiBase
[作者:Strandell, J; Caster, O; Bate, A; Noren, N; Edwards, IR,期刊:Drug safety, 页码:253-266 , 文章类型: Article,,卷期:2011年34-3]
- Background: Adverse drug interaction surveillance in collections of Individual Case Safety Reports (ICSRs) remains underdeveloped. Most efforts to date have focused on disproportionality analysis, but the empirical suppo...
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