- SUMOylation Promotes PML Degradation during Encephalomyocarditis Virus Infection
[作者:El Mchichi, B; Regad, T; Maroui, MA; Rodriguez, MS; Aminev, A; Gerbaud, S; Escriou, N; Dianoux, L; Chelbi-Alix, MK,期刊:Journal of virology, 页码:11634-11645 , 文章类型: Article,,卷期:2010年84-22]
- The promyelocytic leukemia (PML) protein is expressed in the diffuse nuclear fraction of the nucleoplasm and in matrix-associated structures, known as nuclear bodies (NBs). PML NB formation requires the covalent modifica...
- Herpes Simplex Virus Glycoprotein D Interferes with Binding of Herpesvirus Entry Mediator to Its Ligands through Downregulation and Direct Competition
[作者:Stiles, KM; Whitbeck, JC; Lou, HA; Cohen, GH; Eisenberg, RJ; Krummenacher, C,期刊:Journal of virology, 页码:11646-11660 , 文章类型: Article,,卷期:2010年84-22]
- To initiate membrane fusion and virus entry, herpes simplex virus (HSV) gD binds to a cellular receptor such as herpesvirus entry mediator (HVEM). HVEM is a tumor necrosis factor (TNF) receptor family member with four na...
- Species-Specific Regions of Occludin Required by Hepatitis C Virus for Cell Entry
[作者:Michta, ML; Hopcraft, SE; Narbus, CM; Kratovac, Z; Israelow, B; Sourisseau, M; Evans, MJ,期刊:Journal of virology, 页码:11696-11708 , 文章类型: Article,,卷期:2010年84-22]
- Hepatitis C virus (HCV) is a leading cause of liver disease worldwide. As HCV infects only human and chimpanzee cells, antiviral therapy and vaccine development have been hampered by the lack of a convenient small-animal...
- The Varicella-Zoster Virus ORFS/L (ORF0) Gene Is Required for Efficient Viral Replication and Contains an Element Involved in DNA Cleavage
[作者:Kaufer, BB; Smejkal, B; Osterrieder, N,期刊:Journal of virology, 页码:11661-11669 , 文章类型: Article,,卷期:2010年84-22]
- The genome of varicella-zoster virus (VZV), a human alphaherpesvirus, consists of two unique regions, unique long (U-L) and unique short (U-S), each of which is flanked by inverted repeats. During replication, four isome...
- Conserved and Variable Features of Gag Structure and Arrangement in Immature Retrovirus Particles
[作者:de Marco, A; Davey, NE; Ulbrich, P; Phillips, JM; Lux, V; Riches, JD; Fuzik, T; Ruml, T; Krausslich, HG; Vogt, VM; Briggs, JAG,期刊:Journal of virology, 页码:11729-11736 , 文章类型: Article,,卷期:2010年84-22]
- The assembly of retroviruses is driven by oligomerization of the Gag polyprotein. We have used cryo-electron tomography together with subtomogram averaging to describe the three-dimensional structure of in vitro-assemble...
- High-Throughput, Sensitive Quantification of Repopulating Hematopoietic Stem Cell Clones
[作者:Kim, S; Kim, N; Presson, AP; An, DS; Mao, SH; Bonifacino, AC; Donahue, RE; Chow, SA; Chen, ISY,期刊:Journal of virology, 页码:11771-11780 , 文章类型: Article,,卷期:2010年84-22]
- Retroviral vector-mediated gene therapy has been successfully used to correct genetic diseases. However, a number of studies have shown a subsequent risk of cancer development or aberrant clonal growths due to vector ins...
- Antagonism of Type I Interferon Responses by New World Hantaviruses
[作者:Levine, JR; Prescott, J; Brown, KS; Best, SM; Ebihara, H; Feldmann, H,期刊:Journal of virology, 页码:11790-11801 , 文章类型: Article,,卷期:2010年84-22]
- Evasion of interferon (IFN)-mediated antiviral signaling is a common defense strategy for pathogenic RNA viruses. To date, research on IFN antagonism by hantaviruses is limited and has focused on only a subset of the num...
- Virulence-Associated Substitution D222G in the Hemagglutinin of 2009 Pandemic Influenza A(H1N1) Virus Affects Receptor Binding
[作者:Chutinimitkul, S; Herfst, S; Steel, J; Lowen, AC; Ye, JQ; van Riel, D; Schrauwen, EJA; Bestebroer, TM; Koel, B; Burke, DF; Sutherland-Cash, KH; Whittleston, CS; Russell, CA; Wales, DJ; Smith, DJ; Jonges, M; Meijer, A; Koopmans, M; Rimmelzwaan, GF; Kuiken, T; Osterhaus, ADME; Garcia-Sastre, A; Perez, DR; Fouchier, RAM,期刊:Journal of virology, 页码:11802-11813 , 文章类型: Article,,卷期:2010年84-22]
- The clinical impact of the 2009 pandemic influenza A(H1N1) virus (pdmH1N1) has been relatively low. However, amino acid substitution D222G in the hemagglutinin of pdmH1N1 has been associated with cases of severe disease ...
- A 27-Amino-Acid Deletion in the Neuraminidase Stalk Supports Replication of an Avian H2N2 Influenza A Virus in the Respiratory Tract of Chickens
[作者:Sorrell, EM; Song, HC; Pena, L; Perez, DR,期刊:Journal of virology, 页码:11831-11840 , 文章类型: Article,,卷期:2010年84-22]
- The events and mechanisms that lead to interspecies transmission of, and host adaptation to, influenza A virus are unknown; however, both surface and internal proteins have been implicated. Our previous report highlighte...
- Quantifying Antigenic Relationships among the Lyssaviruses
[作者:Horton, DL; McElhinney, LM; Marston, DA; Wood, JLN; Russell, CA; Lewis, N; Kuzmin, IV; Fouchier, RAM; Osterhaus, ADME; Fooks, AR; Smith, DJ,期刊:Journal of virology, 页码:11841-11848 , 文章类型: Article,,卷期:2010年84-22]
- All lyssaviruses cause fatal encephalitis in mammals. There is sufficient antigenic variation within the genus to cause variable vaccine efficacy, but this variation is difficult to characterize quantitatively: sequence ...
- Widespread Horizontal Gene Transfer from Double-Stranded RNA Viruses to Eukaryotic Nuclear Genomes
[作者:Liu, HQ; Fu, YP; Jiang, DH; Li, GQ; Xie, JT; Cheng, JS; Peng, YL; Ghabrial, SA; Yi, XH,期刊:Journal of virology, 页码:11876-11887 , 文章类型: Article,,卷期:2010年84-22]
- Horizontal gene transfer commonly occurs from cells to viruses but rarely occurs from viruses to their host cells, with the exception of retroviruses and some DNA viruses. However, extensive sequence similarity searches ...
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