- Integrin alpha 4 beta 7 Is Downregulated on the Surfaces of Simian Immunodeficiency Virus SIVmac239-Infected Cells
[作者:Budde, ML; Lhost, JJ; Dudley, DM; Rakasz, EG; O'Connor, DH,期刊:Journal of virology, 页码:6344-6351 , 文章类型: Article,,卷期:2010年84-13]
- Simian immunodeficiency virus (SIV) and human immunodeficiency virus (HIV) infection results in an early and enduring depletion of intestinal CD4(+) T cells. SIV and HIV bind integrin alpha 4 beta 7, thereby facilitating...
- Role of Interferon Antagonist Activity of Rabies Virus Phosphoprotein in Viral Pathogenicity
[作者:Ito, N; Moseley, GW; Blondel, D; Shimizu, K; Rowe, CL; Ito, Y; Masatani, T; Nakagawa, K; Jans, DA; Sugiyama, M,期刊:Journal of virology, 页码:6699-6710 , 文章类型: Article,,卷期:2010年84-13]
- The fixed rabies virus (RV) strain Nishigahara kills adult mice after intracerebral inoculation, whereas the chicken embryo fibroblast cell-adapted strain Ni-CE causes nonlethal infection in adult mice. We previously rep...
- Rearranged Genomic RNA Segments Offer a New Approach to the Reverse Genetics of Rotaviruses
[作者:Troupin, C; Dehee, A; Schnuriger, A; Vende, P; Poncet, D; Garbarg-Chenon, A,期刊:Journal of virology, 页码:6711-6719 , 文章类型: Article,,卷期:2010年84-13]
- Group A rotaviruses (RV), members of the Reoviridae family, are a major cause of infantile acute gastroenteritis. The RV genome consists of 11 double-stranded RNA segments. In some cases, an RNA segment is replaced by a ...
- Suppression of a Morphogenic Mutant in Rous Sarcoma Virus Capsid Protein by a Second-Site Mutation: a Cryoelectron Tomography Study
[作者:Butan, C; Lokhandwala, PM; Purdy, JG; Cardone, G; Craven, RC; Steven, AC,期刊:Journal of virology, 页码:6377-6386 , 文章类型: Article,,卷期:2010年84-13]
- Retrovirus assembly is driven by polymerization of the Gag polyprotein as nascent virions bud from host cells. Gag is then processed proteolytically, releasing the capsid protein (CA) to assemble de novo inside maturing ...
- Host Factors Associated with the Sindbis Virus RNA-Dependent RNA Polymerase: Role for G3BP1 and G3BP2 in Virus Replication
[作者:Cristea, IM; Rozjabek, H; Molloy, KR; Karki, S; White, LL; Rice, CM; Rout, MP; Chait, BT; MacDonald, MR,期刊:Journal of virology, 页码:6720-6732 , 文章类型: Article,,卷期:2010年84-13]
- Sindbis virus (SINV) is the prototype member of the Alphavirus genus, whose members cause severe human diseases for which there is no specific treatment. To ascertain host factors important in the replication of the SINV...
- Species-Specific Contribution of the Four C-Terminal Amino Acids of Influenza A Virus NS1 Protein to Virulence
[作者:Soubies, SM; Volmer, C; Croville, G; Loupias, J; Peralta, B; Costes, P; Lacroux, C; Guerin, JL; Volmer, R,期刊:Journal of virology, 页码:6733-6747 , 文章类型: Article,,卷期:2010年84-13]
- Large-scale sequence analyses of influenza viruses revealed that nonstructural 1 (NS1) proteins from avian influenza viruses have a conserved C-terminal ESEV amino acid motif, while NS1 proteins from typical human influe...
- Inhibition of Hepatitis B Virus Replication by MyD88 Involves Accelerated Degradation of Pregenomic RNA and Nuclear Retention of Pre-S/S RNAs
[作者:Li, JH; Lin, SS; Chen, QY; Peng, L; Zhai, JW; Liu, YH; Yuan, ZH,期刊:Journal of virology, 页码:6387-6399 , 文章类型: Article,,卷期:2010年84-13]
- Myeloid differentiation primary response protein 88 (MyD88), which can be induced by alpha interferon (IFN-alpha), has an antiviral activity against the hepatitis B virus (HBV). The mechanism of this antiviral activity r...
- Protein Kinase A Phosphorylation Activates Vpr-Induced Cell Cycle Arrest during Human Immunodeficiency Virus Type 1 Infection
[作者:Barnitz, RA; Wan, FY; Tripuraneni, V; Bolton, DL; Lenardo, MJ,期刊:Journal of virology, 页码:6410-6424 , 文章类型: Article,,卷期:2010年84-13]
- Infection with human immunodeficiency virus type 1 (HIV-1) causes an inexorable depletion of CD4(+) T cells. The loss of these cells is particularly pronounced in the mucosal immune system during acute infection, and the...
- SRp40 and SRp55 Promote the Translation of Unspliced Human Immunodeficiency Virus Type 1 RNA
[作者:Swanson, CM; Sherer, NM; Malim, MH,期刊:Journal of virology, 页码:6748-6759 , 文章类型: Article,,卷期:2010年84-13]
- Nuclear RNA processing events, such as 5' cap formation, 3' polyadenylation, and pre-mRNA splicing, mark mRNA for efficient translation. Splicing enhances translation via the deposition of the exon-junction complex and o...
- Viral Entry Inhibitors Targeted to the Membrane Site of Action
[作者:Porotto, M; Yokoyama, CC; Palermo, LM; Mungall, B; Aljofan, M; Cortese, R; Pessi, A; Moscona, A,期刊:Journal of virology, 页码:6760-6768 , 文章类型: Article,,卷期:2010年84-13]
- The fusion of enveloped viruses with the host cell is driven by specialized fusion proteins to initiate infection. The "class I" fusion proteins harbor two regions, typically two heptad repeat (HR) domains, which are cen...
- Activation of the Inositol (1,4,5)-Triphosphate Calcium Gate Receptor Is Required for HIV-1 Gag Release
[作者:Ehrlich, LS; Medina, GN; Khan, MB; Powell, MD; Mikoshiba, K; Carter, CA,期刊:Journal of virology, 页码:6438-6451 , 文章类型: Article,,卷期:2010年84-13]
- The structural precursor polyprotein, Gag, encoded by all retroviruses, including the human immunodeficiency virus type 1 (HIV-1), is necessary and sufficient for the assembly and release of particles that morphologicall...
- Neuraminidase Receptor Binding Variants of Human Influenza A(H3N2) Viruses Resulting from Substitution of Aspartic Acid 151 in the Catalytic Site: a Role in Virus Attachment?
[作者:Lin, YP; Gregory, V; Collins, P; Kloess, J; Wharton, S; Cattle, N; Lackenby, A; Daniels, R; Hay, A,期刊:Journal of virology, 页码:6769-6781 , 文章类型: Article,,卷期:2010年84-13]
- Changes in the receptor binding characteristics of human H3N2 viruses have been evident from changes in the agglutination of different red blood cells (RBCs) and the reduced growth capacity of recently isolated viruses, ...
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