- Release abilities of adenosine diphosphate from phospholipid vesicles with different membrane properties and their hemostatic effects as a platelet substitute
[作者：Okamura, Y; Katsuno, S; Suzuki, H; Maruyama, H; Handa, M; Ikeda, Y; Takeoka, S,期刊：Journal of controlled release, 页码：373-379 , 文章类型： Article，,卷期：2010年148-3]
- We have constructed phospholipid vesicles with hemostatic activity as a platelet substitute. The vesicles were conjugated with a dodecapeptide (HHLGGAKQAGDV, H12), which is a fibrinogen gamma-chain carboxy-terminal seque...
- Uptake of synthetic Low Density Lipoprotein by leukemic stem cells - a potential stem cell targeted drug delivery strategy
[作者：Zhou, PX; Hatziieremia, S; Elliott, MA; Scobie, L; Crossan, C; Michie, AM; Holyoake, TL; Halbert, GW; Jorgensen, HG,期刊：Journal of controlled release, 页码：380-387 , 文章类型： Article，,卷期：2010年148-3]
- Chronic Myeloid Leukemia (CML) stem/progenitor cells, which over-express Bcr-Abl, respond to imatinib by a reversible block in proliferation without significant apoptosis. As a result, patients are unlikely to be cured o...
- Advances in transcutaneous vaccine delivery: Do all ways lead to Rome?
[作者：Bal, SM; Ding, Z; van Riet, E; Jiskoot, W; Bouwstra, JA,期刊：Journal of controlled release, 页码：266-282 , 文章类型： Review，,卷期：2010年148-3]
- Transcutaneous immunization (TCI) is a promising alternative to vaccine delivery via the subcutaneous and intramuscular routes, due to the unique immunological characteristics of the skin. The increasing knowledge of the...
- In vivo imaging of tumor apoptosis using histone H1-targeting peptide
[作者：Wang, K; Purushotham, S; Lee, JY; Na, MH; Park, H; Oh, SJ; Park, RW; Park, JY; Lee, E; Cho, BC; Song, MN; Baek, MC; Kwak, W; Yoo, J; Hoffman, AS; Oh, YK; Kim, IS; Lee, BH,期刊：Journal of controlled release, 页码：283-291 , 文章类型： Article，,卷期：2010年148-3]
In vivo imaging of apoptosis could allow monitoring of tumor response to cancer treatments such as chemotherapy. Using phage display, we identified the CQRPPR peptide, named ApoPep-1(Apoptosis-targeting Peptide-1), th...
- A novel peptide specifically targeting the vasculature of orthotopic colorectal cancer for imaging detection and drug delivery
[作者：Li, ZJ; Wu, WKK; Ng, SSM; Yu, L; Li, HT; Wong, CCM; Wu, YC; Zhang, L; Ren, SX; Sun, XG; Chan, KM; Cho, CH,期刊：Journal of controlled release, 页码：292-302 , 文章类型： Article，,卷期：2010年148-3]
- Colorectal cancer (CRC) is the third most common malignancy and the fourth most frequent cause of cancer deaths worldwide. Ligand-mediated diagnosis and targeted therapy would have vital clinical applications in cancer t...
- Liposomal pravastatin inhibits tumor growth by targeting cancer-related inflammation
[作者：Coimbra, M; Banciu, M; Fens, MHAM; de Smet, L; Cabaj, M; Metselaar, JM; Storm, G; Schiffelers, RM,期刊：Journal of controlled release, 页码：303-310 , 文章类型： Article，,卷期：2010年148-3]
- The chronic inflammatory environment of tumors is a target for novel antitumor therapeutic strategies. Besides cholesterol lowering effects, statins have been studied for their anti-inflammatory and immunomodulatory prop...
- Structural and immunostimulatory properties of Y-shaped DNA consisting of phosphodiester and phosphorothioate oligodeoxynucleotides
[作者：Matsuoka, N; Nishikawa, M; Mohri, K; Rattanakiat, S; Takakura, Y,期刊：Journal of controlled release, 页码：311-316 , 文章类型： Article，,卷期：2010年148-3]
- V-shape formation increased the immunostimulatory activity of phosphodiester (PO) oligodeoxynucleotides (ODNs) containing CpG motif. In this study, PO CpG ODN or CpG ODN containing nuclease-resistant phosphorothioate (PS...
- High antiangiogenic and low anticoagulant efficacy of orally active low molecular weight heparin derivatives
[作者：Park, JW; Jeon, OC; Kim, SK; Al-Hilal, TA; Jin, SJ; Moon, HT; Yang, VC; Kim, SY; Byun, Y,期刊：Journal of controlled release, 页码：317-326 , 文章类型： Article，,卷期：2010年148-3]
- Heparin, an anticoagulant that is widely used clinically, is also known to bind to several kinds of proteins through electrostatic interactions because of its polyanionic character. These interactions are mediated by the...
- Improved DNA vaccination by skin-targeted delivery using dry-coated densely-packed microprojection arrays
[作者：Chen, XF; Kask, AS; Crichton, ML; McNeilly, C; Yukiko, S; Dong, LC; Marshak, JO; Jarrahian, C; Fernando, GJP; Chen, DX; Koelle, DM; Kendall, MAF,期刊：Journal of controlled release, 页码：327-333 , 文章类型： Article，,卷期：2010年148-3]
- HSV-2-gD2 DNA vaccine was precisely delivered to immunologically sensitive regions of the skin epithelia using dry-coated microprojection arrays. These arrays delivered a vaccine payload to the epidermis and the upper de...
- Delivery of messenger RNA using poly(ethylene imine)-poly(ethylene glycol)-copolymer blends for polyplex formation: Biophysical characterization and in vitro transfection properties
[作者：Debus, H; Baumhof, P; Probst, J; Kissel, T,期刊：Journal of controlled release, 页码：334-343 , 文章类型： Article，,卷期：2010年148-3]
- Nucleic acid based therapies have so far mainly been focused on plasmid DNA (pDNA), small interfering RNA (siRNA), antisense and immunostimulatory oligonucleotides. Messenger RNA (mRNA) was the subject of only a few stud...
- Paclitaxel-loaded Pluronic nanoparticles formed by a temperature-induced phase transition for cancer therapy
[作者：Oh, KS; Song, JY; Cho, SH; Lee, BS; Kim, SY; Kim, K; Jeon, H; Kwon, IC; Yuk, SH,期刊：Journal of controlled release, 页码：344-350 , 文章类型： Article，,卷期：2010年148-3]
- We prepared nanoparticles by a temperature-induced phase transition in a mixture of Pluronic F-68 and liquid PEG (polyethylene glycol, molecular weight: 400) containing paclitaxel (PTX) with a fast, simple, continuous an...
- Mannosylated solid lipid nanoparticles as vectors for site-specific delivery of an anti-cancer drug
[作者：Jain, A; Agarwal, A; Majumder, S; Lariya, N; Khaya, A; Agrawal, H; Majumdar, S; Agrawal, GP,期刊：Journal of controlled release, 页码：359-367 , 文章类型： Article，,卷期：2010年148-3]
- The purpose of the present study was to investigate the tumor targeting potential of surface tailored solid lipid nanoparticles (SLNs) loaded with an anti-cancer drug doxorubicin HCl (DOX). DOX encapsulating SLNs were pr...
- New doxorubicin-loaded phospholipid microbubbles for targeted tumor therapy: In-vivo characterization
[作者：Tinkov, S; Coester, C; Serba, S; Geis, NA; Katus, HA; Winter, G; Bekeredjian, R,期刊：Journal of controlled release, 页码：368-372 , 文章类型： Article，,卷期：2010年148-3]
- Doxorubicin(DOX) is a potent chemotherapy drug that is often limited by severe adverse effects such as cardiac toxicity and myelosupression. Drug targeting with non invasive techniques would be desirable, aiming at incre...
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