- Epigenomic targets for the treatment of respiratory disease
[作者:Bowman, RV; Wright, CM; Davidson, MR; Francis, SMS; Yang, IA; Fong, KM,期刊:Expert Opinion on Therapeutic Targets, 页码:625-640 , 文章类型: Review,,卷期:2009年13-6]
- Background: A number of processes lead to epigenetic and epigenomic modifications. Objective: To address the importance of epigenomics in respiratory disease. Methods: Studies of epigenomics were analysed in relation to ...
- Targeting ASK1 in ER stress-related neurodegenerative diseases
[作者:Homma, K; Katagiri, K; Nishitoh, H; Ichijot, H,期刊:Expert Opinion on Therapeutic Targets, 页码:653-664 , 文章类型: Review,,卷期:2009年13-6]
- The accumulation of malfolded proteins in the endoplasmic reticulum (ER) induces ER stress, leading to the disturbance of ER function. To restore ER function and ER homeostasis, cells possess a highly specific ER quality...
- The potential role of estrogen receptors and the SRC family as targets for the treatment of breast cancer
[作者:Spears, M; Bartlettt, J,期刊:Expert Opinion on Therapeutic Targets, 页码:665-674 , 文章类型: Review,,卷期:2009年13-6]
- Background: Breast cancer has a number of subtypes, the main ones are estrogen-receptor (ER)-positive, luminal type A and B. Treatment selection, with respect to hormonal therapy, is based upon ER expression. Whilst for ...
- Glioblastoma multiforme: a review of therapeutic targets
[作者:Kanu, OO; Mehta, A; Di, CH; Lin, NJ; Bortoff, K; Bigner, DD; Yan, H; Adamson, DC,期刊:Expert Opinion on Therapeutic Targets, 页码:701-718 , 文章类型: Review,,卷期:2009年13-6]
- Glioblastoma is the commonest primary brain tumor, as well as the deadliest. malignant gliomas such as glioblastoma multiforme (GBM) present some of the greatest challenges in the management of cancer patients worldwide,...
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