- Src family kinase oncogenic potential and pathways in prostate cancer as revealed by AZD0530
[作者:Chang, YM; Bai, L; Liu, S; Yang, JC; Kung, HJ; Evans, CP,期刊:Oncogene, 页码:6365-6375 , 文章类型: Article,,卷期:2008年27-49]
- Prostate cancer is the most frequently diagnosed cancer in American men. We have previously demonstrated that Src mediates androgen-independent proliferation in prostate cancer. We sought to investigate the Src-mediated ...
- hPMC2 is required for recruiting an ER beta coactivator complex to mediate transcriptional upregulation of NQO1 and protection against oxidative DNA damage by tamoxifen
[作者:Sripathy, SP; Chaplin, LJ; Gaikwad, NW; Rogan, EG; Montano, MM,期刊:Oncogene, 页码:6376-6384 , 文章类型: Article,,卷期:2008年27-49]
- In the presence of ER beta, trans-hydroxytamoxifen (TOT) protects cells against 17 beta-estradiol(E-2)-induced oxidative DNA damage (ODD) and this correlates with increased expression of the antioxidative enzyme quinone ...
- Pituitary tumor transforming gene 1 regulates Aurora kinase A activity
[作者:Tong, Y; Ben-Shlomo, A; Zhou, C; Wawrowsky, K; Melmed, S,期刊:Oncogene, 页码:6385-6395 , 文章类型: Article,,卷期:2008年27-49]
- Pituitary tumor transforming gene 1 (PTTG1), a transforming gene highly expressed in several cancers, is a mammalian securin protein regulating both G1/S and G2/M phases. Using protein array screening, we showed PTTG1 in...
- HPV-16 E5 oncoprotein upregulates lipid raft components caveolin-1 and ganglioside GM1 at the plasma membrane of cervical cells (vol 27, pg 1071, 2008)
[作者:Suprynowicz, FA; Disbrow, GL; Krawczyk, E; Simic, V; Lantzky, K; Schlegel, R,期刊:Oncogene, 页码:6396-6396 , 文章类型: Correction,,卷期:2008年27-49]
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- Bone morphogenetic protein signaling enhances invasion and bone metastasis of breast cancer cells through Smad pathway
[作者:Katsuno, Y; Hanyu, A; Kanda, H; Ishikawa, Y; Akiyama, F; Iwase, T; Ogata, E; Ehata, S; Miyazono, K; Imamura, T,期刊:Oncogene, 页码:6322-6333 , 文章类型: Article,,卷期:2008年27-49]
- Transforming growth factor (TGF)-beta is known to promote tumor invasion and metastasis. Although bone morphogenetic proteins ( BMPs), members of the TGF-beta family, are expressed in a variety of human carcinoma cell li...
- PP2A-dependent disruption of centrosome replication and cytoskeleton organization in Drosophila by SV40 small tumor antigen
[作者:Kotadia, S; Kao, LR; Comerford, SA; Jones, RT; Hammer, RE; Megraw, TL,期刊:Oncogene, 页码:6334-6346 , 文章类型: Article,,卷期:2008年27-49]
- Viruses of the DNA tumor virus family share the ability to transform vertebrate cells through the action of virus-encoded tumor antigens that interfere with normal cell physiology. They accomplish this very efficiently b...
- Matrix metalloproteinase-11/stromelysin-3 exhibits collagenolytic function against collagen VI under normal and malignant conditions
[作者:Motrescu, ER; Blaise, S; Etique, N; Messaddeq, N; Chenard, MP; Stoll, I; Tomasetto, C; Rio, MC,期刊:Oncogene, 页码:6347-6355 , 文章类型: Article,,卷期:2008年27-49]
- The substrate of matrix metalloproteinase 11 (MMP11) remains unknown. We have recently shown that MMP11 is a negative regulator of adipogenesis, able to reduce and even to revert mature adipocyte differentiation. Here, w...
- Evidence for Hox and E2A-PBX1 collaboration in mouse T-cell leukemia
[作者:Bijl, J; Krosl, J; Lebert-Ghali, CE; Vacher, J; Mayotte, N; Sauvageau, G,期刊:Oncogene, 页码:6356-6364 , 文章类型: Article,,卷期:2008年27-49]
- Using murine Moloney leukemia virus (MMLV)-based proviral insertional mutagenesis, we previously showed a preferential targeting of a small region in the Hoxa gene locus in E2A-PBX1-induced lymphoid leukemia resulting in...
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