- The Tripeptide KdPT Protects from Intestinal Inflammation and Maintains Intestinal Barrier Function
[作者：Bettenworth, D; Buyse, M; Bohm, M; Mennigen, R; Czorniak, I; Kannengiesser, K; Brzoska, T; Luger, TA; Kucharzik, T; Domschke, W; Maaser, C; Lugering, A,期刊：American Journal of Pathology, 页码：1230-1242 , 文章类型： Article，,卷期：2011年179-3]
- Treatment options for inflammatory bowel disease (IBD) are incompletely helpful, and surgery is often needed. One promising class of future therapeutic agents for IBD is melanocortin-related peptides, which exhibit poten...
- Colony-Stimulating Factor-1 Promotes Kidney Growth and Repair via Alteration of Macrophage Responses
[作者：Alikhan, MA; Jones, CV; Williams, TM; Beckhouse, AG; Fletcher, AL; Kett, MM; Sakkal, S; Samuel, CS; Ramsay, RG; Deane, JA; Wells, CA; Little, MH; Hume, DA; Ricardo, SD,期刊：American Journal of Pathology, 页码：1243-1256 , 文章类型： Article，,卷期：2011年179-3]
- Colony-stimulating factor (CSF)-1 controls the survival, proliferation, and differentiation of macrophages, which are recognized as scavengers and agents of the innate and the acquired immune systems. Because of their pl...
- Involvement of GLTSCR2 in the DNA Damage Response
[作者：Kim, JY; Seok, KO; Kim, YJ; Bae, WK; Lee, S; Park, JH,期刊：American Journal of Pathology, 页码：1257-1264 , 文章类型： Article，,卷期：2011年179-3]
- The cellular DNA damage response (DDR) ensures genomic stability and protects against genotoxic stresses. Conversely, defects in the DDR contribute to genome instability, with the resulting accumulated genetic changes ca...
- EMMPRIN Modulates Epithelial Barrier Function through a MMP-Mediated Occludin Cleavage Implications in Dry Eye Disease
[作者：Huet, E; Vallee, B; Delbe, J; Mourah, S; Pruliere-Escabasse, V; Tremouilleres, M; Kadomatsu, K; Doan, S; Baudouin, C; Menashi, S; Gabison, EE,期刊：American Journal of Pathology, 页码：1278-1286 , 文章类型： Article，,卷期：2011年179-3]
- Dry eye is a common disease that develops as a result of alteration of tear fluid, leading to osmotic stress and a perturbed epithelial barrier. Matrix metalloproteinase-9 (MMP-9) may be important in dry eye disease, as ...
- Regression of Allograft Airway Fibrosis The Role of MMP-Dependent Tissue Remodeling in Obliterative Bronchiolitis after Lung Transplantation
[作者：Sato, M; Hwang, DM; Guan, ZH; Yeung, JC; Anraku, M; Wagnetz, D; Hirayama, S; Waddell, TK; Liu, MY; Keshavjee, S,期刊：American Journal of Pathology, 页码：1287-1300 , 文章类型： Article，,卷期：2011年179-3]
- Obliterative bronchiolitis after lung transplantation is a chronic inflammatory and fibrotic condition of small airways. The fibrosis associated with obliterative bronchiolitis might be reversible. Matrix metalloproteina...
- Orally Administered Prion Protein Is Incorporated by M Cells and Spreads into Lymphoid Tissues with Macrophages in Prion Protein Knockout Mice
[作者：Takakura, I; Miyazawa, K; Kanaya, T; Itani, W; Watanabe, K; Ohwada, S; Watanabe, H; Hondo, T; Rose, MT; Mori, T; Sakaguchi, S; Nishida, N; Katamine, S; Yamaguchi, T; Aso, H,期刊：American Journal of Pathology, 页码：1301-1309 , 文章类型： Article，,卷期：2011年179-3]
- Transmissible spongiform encephalopathies are fatal neurodegenerative diseases. Infection by the oral route is assumed to be important, although its pathogenesis is not understood. Using prion protein (PrP) knockout mice...
- Regulation of CRIg Expression and Phagocytosis in Human Macrophages by Arachidonate, Dexamethasone, and Cytokines
[作者：Gorgani, NN; Thathaisong, U; Mukaro, VRS; Poungpair, O; Tirimacco, A; Hii, CST; Ferrante, A,期刊：American Journal of Pathology, 页码：1310-1318 , 文章类型： Article，,卷期：2011年179-3]
- Although the importance of the macrophage complement receptor immunoglobulin (CRIg) in the phagocytosis of complement opsonized bacteria and in inflammation has been established, the regulation of CRIg expression remains...
- Chronic Wasting Disease Prion Trafficking via the Autonomic Nervous System
[作者：Seelig, DM; Mason, GL; Telling, GC; Hoover, EA,期刊：American Journal of Pathology, 页码：1319-1328 , 文章类型： Article，,卷期：2011年179-3]
- Chronic wasting disease (CWD) is a fatal spongiforrn encephalopathy that is efficiently transmitted among members of the mammalian family Cervidae, including deer, elk, and moose. Typical of prion diseases, CWD is charac...
- Pathogen-Derived Oligosaccharides Improve Innate Immune Response to Intracellular Parasite Infection
[作者：Osanya, A; Song, EH; Metz, K; Shimak, RM; Boggiatto, PM; Huffman, E; Johnson, C; Hostetter, JM; Pohl, NLB; Petersen, CA,期刊：American Journal of Pathology, 页码：1329-1337 , 文章类型： Article，,卷期：2011年179-3]
- Pathogen glycolipids, including Leisbmania spp. lipophosphoglycan (LPG) and Mycobacterium tuberculosis mannosylated lipoarabinomannan (ManLAM), modulate essential interactions with host phagocytic cells. Polysaccharide a...
- Intact Pericellular Matrix of Articular Cartilage Is Required for Unactivated Discoidin Domain Receptor 2 in the Mouse Model
[作者：Xu, L; Polur, I; Servais, JM; Hsieh, S; Lee, PL; Goldring, MB; Li, YF,期刊：American Journal of Pathology, 页码：1338-1346 , 文章类型： Article，,卷期：2011年179-3]
- Increased expression of the discoidin domain receptor 2 (DDR2) results from its interaction with collagen type II. This induces expression of matrix metalloproteinase (MMP)-13, leading to osteoarthritis (OA). To investig...
- Mesenchymal Stem Cells Stably Transduced with a Dominant-Negative Inhibitor of CCL2 Greatly Attenuate Bleomycin-Induced Lung Damage
[作者：Saito, S; Nakayama, T; Hashimoto, N; Miyata, Y; Egashira, K; Nakao, N; Nishiwaki, S; Hasegawa, M; Hasegawa, Y; Naoe, T,期刊：American Journal of Pathology, 页码：1088-1094 , 文章类型： Article，,卷期：2011年179-3]
- Acute respiratory distress syndrome (ARDS) is a crippling disease with no effective therapy characterized by progressive dyspnea. Mesenchymal stem cells (MSCs) have emerged as a new therapeutic modality for ARDS because ...
- MyD88 Deficiency Ameliorates beta-Amyloidosis in an Animal Model of Alzheimer's Disease
[作者：Lim, JE; Kou, JH; Song, M; Pattanayak, A; Jin, JJ; Lalonde, R; Fukuchi, K,期刊：American Journal of Pathology, 页码：1095-1103 , 文章类型： Article，,卷期：2011年179-3]
- The accumulation of beta-amyloid protein (A beta) in the brain is thought to be a primary etiologic event in Alzheimer's disease (AD). Fibrillar A beta plaques, a hallmark of AD abnormality, are closely associated with a...
- In the Eye of Experimental Cerebral Malaria
[作者：Saggu, R; Faille, D; Grau, GE; Cozzone, PJ; Viola, A,期刊：American Journal of Pathology, 页码：1104-1109 , 文章类型： Article，,卷期：2011年179-3]
- Cerebral malaria is the most severe complication of Plasmodium falciparum infection, accounting for 1 million deaths per year. We characterized the murine disease using in vivo magnetic resonance imaging (Mm) at 4.7 T, p...
|