- Rimonabant inhibits human colon cancer cell growth and reduces the formation of precancerous lesions in the mouse colon
[作者:Santoro, A; Pisanti, S; Grimaldi, C; Izzo, AA; Borrelli, F; Proto, MC; Malfitano, AM; Gazzerro, P; Laezza, C; Bifulco, M,期刊:International Journal of Cancer, 页码:996-1003 , 文章类型: Article,,卷期:2009年125-5]
- The selective CB1 receptor antagonist rimonabant (SR141716) was shown to perform a number of biological effects in several pathological conditions. Emerging findings demonstrate that rimonabant exerts antitumor action in...
- Increased production and secretion of HGF alpha-chain and an antagonistic HGF fragment in a human breast cancer progression model
[作者:Wright, TG; Singh, VK; Li, JJ; Foley, JH; Miller, F; Jia, ZC; Elliott, BE,期刊:International Journal of Cancer, 页码:1004-1015 , 文章类型: Article,,卷期:2009年125-5]
- Invasive human breast carcinomas frequently coexpress increased hepatocyte growth factor (HGF) and its receptor Met, suggesting that establishment of an autocrine HGF loop is important in malignant disease. This study ex...
- CXC-chemokine/CXCR2 biological axis promotes angiogenesis in vitro and in vivo in pancreatic cancer
[作者:Matsuo, Y; Raimondo, M; Woodward, TA; Wallace, MB; Gill, KR; Tong, ZM; Burdick, MD; Yang, ZJ; Strieter, RM; Hoffman, RM; Guha, S,期刊:International Journal of Cancer, 页码:1027-1037 , 文章类型: Article,,卷期:2009年125-5]
- Angiogenesis is essential for tumor growth and metastasis. Although ELR+-CXC-chemokines and their corresponding receptor, CXC-receptor 2 (CXCR2), are known mediators of angiogenesis, little is known about their role in p...
- Functional analysis of the-2548G/A leptin gene polymorphism in breast cancer
[作者:Terrasi, M; Fiorio, E; Mercanti, A; Koda, M; Moncada, CA; Sulkowski, S; Merali, S; Russo, A; Surmacz, E,期刊:International Journal of Cancer, 页码:1038-1044 , 文章类型: Article,,卷期:2009年125-5]
- Leptin is overexpressed in human breast tumors and is produced by breast cancer cells in response to obesity-related stimuli. The leptin promoter polymorphism Lep-2548G/A can be associated with increased leptin secretion...
- Estrogen regulation of thrombospondin-1 in human breast cancer cells
[作者:Hyder, SM; Liang, YY; Wu, JB,期刊:International Journal of Cancer, 页码:1045-1053 , 文章类型: Article,,卷期:2009年125-5]
- Expression of thrombospondin-1 (TSP-1), a large extracellular matrix protein, has been associated with modulation of angiogenesis and tumor growth. Both pro and antiangiogenic properties of TSP-1 have been described, and...
- Combined targeting of interleukin-6 and vascular endothelial growth factor potently inhibits glioma growth and invasiveness
[作者:Saidi, A; Hagedorn, M; Allain, N; Verpelli, C; Sala, C; Bello, L; Bikfalvi, A; Javerzat, S,期刊:International Journal of Cancer, 页码:1054-1064 , 文章类型: Article,,卷期:2009年125-5]
- Interleukin-6 (IL6) and vascular endothelial growth factor (VEGFA) are abundantly produced by glioma cells and contribute to malignancy by promoting angiogenesis, cell proliferation and resistance to apoptosis. We compar...
- Enhanced invasiveness of drug-resistant acute myeloid leukemia cells through increased expression of matrix metalloproteinase-2
[作者:Song, JH; Kim, SH; Cho, D; Lee, IK; Kim, HJ; Kim, TS,期刊:International Journal of Cancer, 页码:1074-1081 , 文章类型: Article,,卷期:2009年125-5]
- The acquired drug resistance as well as extramedullary tissue infiltration of leukemic cells is a major obstacle in leukemia treatment. Excessive egress of leukemia cell blasts results in invasion into various organs or ...
- Functional coexpression of Interleukin (IL)-7 and its receptor (IL-7R) on Hodgkin and Reed-Sternberg cells: Involvement of IL-7 in tumor cell growth and microenvironmental interactions of Hodgkin's lymphoma
[作者:Cattaruzza, L; Gloghini, A; Olivo, K; Di Francia, R; Lorenzon, D; De Filippi, R; Carbone, A; Colombatti, A; Pinto, A; Aldinucci, D,期刊:International Journal of Cancer, 页码:1092-1101 , 文章类型: Article,,卷期:2009年125-5]
- The clinical and pathological features of classical Hodgkin lymphoma (cHL) mirror an abnormal tissue and systemic immune response due to the production of a variety of cytokines and chemokines by the malignant Hodgkin-Re...
- XRCC1 gene polymorphisms and esophageal squamous cell carcinoma risk in Chinese population: A meta-analysis of case-control studies
[作者:Dai, LP; Wang, KJ; Zhang, JY; Lv, QJ; Wu, XB; Wang, YP,期刊:International Journal of Cancer, 页码:1102-1109 , 文章类型: Article,,卷期:2009年125-5]
- Two non-synonymous polymorphisms Arg194Trp and Arg399Gln in the DNA-base excision repair gene X-ray repair cross-complementing group 1 (XRCC1) have been implicated in risk for esophageal cancer. However, the results from...
- Dietary and stored iron as predictors of breast cancer risk: A nested case-control study in Shanghai
[作者:Moore, AB; Shannon, J; Chen, C; Lampe, JW; Ray, RM; Lewis, SK; Lin, MG; Stalsberg, H; Thomas, DB,期刊:International Journal of Cancer, 页码:1110-1117 , 文章类型: Article,,卷期:2009年125-5]
- Increases in risk of breast cancer in successive generations of migrants to the United States from China and rapid temporal changes in incidence rates in China following social and economic changes clearly implicate envi...
- Meat and fat intake and pancreatic cancer risk in the Netherlands Cohort Study
[作者:Heinen, MM; Verhage, BAJ; Goldbohm, RA; van den Brandt, PA,期刊:International Journal of Cancer, 页码:1118-1126 , 文章类型: Article,,卷期:2009年125-5]
- Meat contains numerous carcinogens, such as heterocyclic amines, polycyclic aromatic hydrocarbons, and N-nitroso compounds, which can be derived either from natural food or during the process of food preparation. These c...
- Performance of immunochemical faecal occult blood test in colorectal cancer screening in average-risk population according to positivity threshold and number of samples
[作者:Guittet, L; Bouvier, V; Mariotte, N; Vallee, JP; Levillain, R; Tichet, J; Launoy, G,期刊:International Journal of Cancer, 页码:1127-1133 , 文章类型: Article,,卷期:2009年125-5]
- Immunochemical faecal occult blood tests (I-FORT) detect more effectively advanced neoplasia than guaiac tests (G-FOBT). The study aim was to compare the performance of an I-FOBT whilst varying the positivity threshold a...
- Genetic modulation of ADH1B and ALDH2 polymorphisms with regard to alcohol and tobacco consumption for younger aged esophageal squamous cell carcinoma diagnosis
[作者:Lee, CH; Wu, DC; Wu, IC; Goan, YG; Lee, JM; Chou, SH; Chan, TF; Huang, HL; Hung, YH; Huang, MC; Lai, TC; Wang, TN; Lan, CCE; Tsai, S; Lin, WY; Wu, MT,期刊:International Journal of Cancer, 页码:1134-1142 , 文章类型: Article,,卷期:2009年125-5]
- Genetic variants in alcohol dehydrogenase-1B (ADH1B) and aldehyde dehydrogenase-2 (ALDH2) genes modulate acetaldehyde removal upon alcohol ingestion. Although these genetic vulnerabilities have been linked to higher esop...
|