- BM88/Cend1 expression levels are critical for proliferation and differentiation of subventricular zone-derived neural precursor cells
[作者:Katsimpardi, L; Gaitanou, M; Malnou, CE; Lledo, PM; Charneau, P; Matsas, R; Thomaidou, D,期刊:Stem Cells, 页码:1796-1807 , 文章类型: Article,,卷期:2008年26-7]
-
- Molecular mechanism of systemic delivery of neural precursor cells to the brain: Assembly of brain endothelial apical cups and control of transmigration by CD44
[作者:Rampon, C; Weiss, N; Deboux, C; Chaverot, N; Miller, F; Buchet, D; Tricoire-Leignel, H; Cazaubon, S; Evercooren, ABV; Couraud, PO,期刊:Stem Cells, 页码:1673-1682 , 文章类型: Article,,卷期:2008年26-7]
- Systemically injected neural precursor cells (NPCs) were unexpectedly shown to reach the cerebral parenchyma and induce recovery in various diffuse brain pathologies, including animal models of multiple sclerosis. Howeve...
- Transforming growth factor beta cooperates with persephin for dopaminergic phenotype induction
[作者:Roussa, E; Oehlke, O; Rahhal, B; Heermann, S; Heidrich, S; Wiehle, M; Krieglstein, K,期刊:Stem Cells, 页码:1683-1694 , 文章类型: Article,,卷期:2008年26-7]
- The aim of the present study was to investigate the putative cooperative effects of transforming growth factor beta (TGF-beta) and glial cell line-derived neurotrophic factor (GDNF) family ligands in the differentiation ...
- Novel cardiac precursor-like cells from human menstrual blood-derived mesenchymal cells
[作者:Hida, N; Nishiyama, N; Miyoshi, S; Kira, S; Segawa, K; Uyama, T; Mori, T; Miyado, K; Ikegami, Y; Cui, C; Kiyono, T; Kyo, S; Shimizu, T; Okano, T; Sakamoto, M; Ogawa, S; Umezawa, A,期刊:Stem Cells, 页码:1695-1704 , 文章类型: Article,,卷期:2008年26-7]
- Stem cell therapy can help repair damaged heart tissue. Yet many of the suitable cells currently identified for human use are difficult to obtain and involve invasive procedures. In our search for novel stem cells with a...
- Lineage selection of functional and cryopreservable human embryonic stem cell-derived neurons
[作者:Ladewig, J; Koch, P; Endl, E; Meiners, B; Opitz, T; Couillard-Despres, S; Aigner, L; Brustle, O,期刊:Stem Cells, 页码:1705-1712 , 文章类型: Article,,卷期:2008年26-7]
- A major prerequisite for the biomedical application of human embryonic stem cells (hESC) is the derivation of defined and homogeneous somatic cell types. Here we present a human doublecortin (DCX) promoter-based lineage-...
- Hypoxia enhances tumor stemness by increasing the invasive and tumorigenic side population fraction
[作者:Das, B; Tsuchida, R; Malkin, D; Koren, G; Baruchel, S; Yeger, H,期刊:Stem Cells, 页码:1818-1830 , 文章类型: Article,,卷期:2008年26-7]
- Although advances have been made in understanding the role of hypoxia in the stem cell niche, almost nothing is known about a potentially similar role of hypoxia in maintaining the tumor stem cell (TSC) niche. Here we sh...
- Lentiviral-transduced human mesenchymal stem cells persistently express therapeutic levels of enzyme in a xenotransplantation model of human disease
[作者:Meyerrose, TE; Roberts, M; Ohlemiller, KK; Vogler, CA; Wirthlin, L; Nolta, JA; Sands, MS,期刊:Stem Cells, 页码:1713-1722 , 文章类型: Article,,卷期:2008年26-7]
- Bone marrow-derived mesenchymal stem cells (MSCs) are a promising platform for cell- and gene-based treatment of inherited and acquired disorders. We recently showed that human MSCs distribute widely in a murine xenotran...
- Molecular signature of cardiomyocyte clusters derived from human embryonic stem cells
[作者:Synnergren, J; Akesson, K; Dahlenborg, K; Vidarsson, H; Ameen, C; Steel, D; Lindahl, A; Olsson, B; Sartipy, P,期刊:Stem Cells, 页码:1831-1840 , 文章类型: Article,,卷期:2008年26-7]
- Human embryonic stem cells (hESCs) can differentiate in vitro into spontaneously contracting cardiomyocytes (CMs). These cells may prove extremely useful for various applications in basic research, drug discovery, and re...
- Costimulation blockade induces tolerance to HESC transplanted to the testis and induces regulatory T-cells to HESC transplanted into the heart
[作者:Grinnemo, KH; Genead, R; Kumagai-Braesch, M; Andersson, A; Danielsson, C; Mansson-Broberg, A; Dellgren, G; Stromberg, AM; Ekberg, H; Hovatta, O; Sylven, C; Corbascio, M,期刊:Stem Cells, 页码:1850-1857 , 文章类型: Article,,卷期:2008年26-7]
- In order to study the ability of costimulation blockade to induce tolerance to human embryonic stem cells (HESC), severe combined immunodeficient (SCID), and immunocompetent C57BL/6 mice treated with costimulation blocka...
- CD117-positive cells in adult human heart are localized in the subepicardium, and their activation is associated with laminin-1 and alpha(6) integrin expression
[作者:Castaldo, C; Di Meglio, F; Nurzynska, D; Romano, G; Maiello, C; Bancone, C; Muller, P; Bohm, M; Cotrufo, M; Montagnani, S,期刊:Stem Cells, 页码:1723-1731 , 文章类型: Article,,卷期:2008年26-7]
- CD117-positive cells contributing to cardiac cell turnover in normal and pathological conditions have recently been described in adult human heart. Since the precise spatial and temporal expression of extracellular matri...
- Downregulation of signal transducer and activator of transcription 5 (STAT5) in CD34(+) cells promotes megakaryocytic development, whereas activation of STAT5 drives erythropoiesis
[作者:Olthof, SG; Fatrai, S; Drayer, AL; Tyl, MR; Vellenga, E; Schuringa, JJ,期刊:Stem Cells, 页码:1732-1742 , 文章类型: Article,,卷期:2008年26-7]
- Although it has been proposed that the common myeloid progenitor gives rise to granulocyte/monocyte progenitors and megakaryocyte/erythroid progenitors (MEP), little is known about molecular switches that determine wheth...
- A novel isolation technique of progenitor cells in human corneal epithelium using non-tissue culture dishes
[作者:Yokoo, S; Yamagami, S; Shimada, T; Usui, T; Sato, TA; Amano, S; Araie, M; Hamuro, J,期刊:Stem Cells, 页码:1743-1748 , 文章类型: Article,,卷期:2008年26-7]
- The existence of adult stem cells or progenitor cells in the human corneal epithelium (i.e., self-renewing squamous cells) has long been suggested, but these cells have not yet been isolated. Here we describe a novel iso...
- Paraxial mesodermal progenitors derived from mouse embryonic stem cells contribute to muscle regeneration via differentiation into muscle satellite cells
[作者:Sakurai, H; Okawa, Y; Inami, Y; Nishio, N; Isobea, K,期刊:Stem Cells, 页码:1865-1873 , 文章类型: Article,,卷期:2008年26-7]
- Pluripotent embryonic stem (ES) cells hold great potential for cell-based therapies. Although several recent studies have reported the potential of ES cell-derived progenitors for skeletal muscle regeneration, how the ce...
- Ex vivo pretreatment with melatonin improves survival, proangiogenic/mitogenic activity, and efficiency of mesenchymal stem cells injected into ischemic kidney
[作者:Mias, C; Trouche, E; Seguelas, MH; Calcagno, F; Dignat-George, F; Sabatier, F; Piercecchi-Marti, MD; Daniel, L; Bianchi, P; Calise, D; Bourin, P; Parini, A; Cussac, D,期刊:Stem Cells, 页码:1749-1757 , 文章类型: Article,,卷期:2008年26-7]
- Bone marrow mesenchymal stem cells (MSCs) have shown great potential in cell therapy of solid organs. Approaches to improving the ability of grafted MSCs to survive and secrete paracrine factors represent one of the chal...
|