- Contributions of extravascular and intravascular cells to fibrin network formation, structure, and stability
[作者:Campbell, RA; Overmyer, KA; Selzman, CH; Sheridan, BC; Wolberg, AS,期刊:Blood, 页码:4886-4896 , 文章类型: Article,,卷期:2009年114-23]
- Fibrin is essential for hemostasis; however, abnormal fibrin formation is hypothesized to increase thrombotic risk. We previously showed that in situ thrombin generation on a cell's surface modulates the 3-dimensional st...
- Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activity
[作者:Nystrom, A; Shaik, ZP; Gullberg, D; Krieg, T; Eckes, B; Zent, R; Pozzi, A; Iozzo, RV,期刊:Blood, 页码:4897-4906 , 文章类型: Article,,卷期:2009年114-23]
- Endorepellin, the C-terminal domain of perlecan, is a powerful angiogenesis inhibitor. To dissect the mechanism of endorepellin-mediated endothelial silencing, we used an antibody array against multiple tyrosine kinase r...
- Primary radiotherapy showed favorable outcome in treating extranodal nasal-type NK/T-cell lymphoma in children and adolescents
[作者:Wang, ZY; Li, YX; Wang, WH; Jin, J; Wang, H; Song, YW; Liu, QF; Wang, SL; Liu, YP; Qi, SN; Fang, H; Liu, XF; Yu, ZH,期刊:Blood, 页码:4771-4776 , 文章类型: Article,,卷期:2009年114-23]
- Extranodal nasal-type natural killer (NK)/T-cell lymphoma is rarely observed in children and adolescents. We aim to investigate the clinical features, prognosis, and treatment outcomes in these patients. Thirty-seven pat...
- Intracranial hemorrhage (ICH) in children with immune thrombocytopenia (ITP): study of 40 cases
[作者:Psaila, B; Petrovic, A; Page, LK; Menell, J; Schonholz, M; Bussel, JB,期刊:Blood, 页码:4777-4783 , 文章类型: Article,,卷期:2009年114-23]
- Intracranial hemorrhage (ICH) is a rare but devastating complication of childhood immune thrombocytopenia purpura (ITP). A survey of ICH from 1987 to 2000 identified cases of ICH in childhood ITP in the United States. Fo...
- Generation of Epstein-Barr virus-specific cytotoxic T lymphocytes resistant to the immunosuppressive drug tacrolimus (FK506)
[作者:De Angelis, B; Dotti, G; Quintarelli, C; Huye, LE; Zhang, L; Zhang, M; Pane, F; Heslop, HE; Brenner, MK; Rooney, CM; Savoldo, B,期刊:Blood, 页码:4784-4791 , 文章类型: Article,,卷期:2009年114-23]
- Adoptive transfer of autologous Epstein-Barr virus-specific cytotoxic T lymphocytes (EBV-CTLs) to solid organ transplant ( SOT) recipients has been shown safe and effective for the treatment of EBV-associated posttranspl...
- Generation of EBV-specific cytotoxic T cells that are resistant to calcineurin inhibitors for the treatment of posttransplantation lymphoproliferative disease
[作者:Brewin, J; Mancao, C; Straathof, K; Karlsson, H; Samarasinghe, S; Amrolia, PJ; Pule, M,期刊:Blood, 页码:4792-4803 , 文章类型: Article,,卷期:2009年114-23]
- Epstein-Barr virus (EBV)-driven post-transplantation lymphoproliferative disease (PTLD) is a serious complication of immunosuppression after either stem cell transplantation (SCT) or solid organ transplantation (SOT). Ad...
- Systematic in vivo structure-function analysis of p300 in hematopoiesis
[作者:Kimbrel, EA; Lemieux, ME; Xia, XB; Davis, TN; Rebel, VI; Kung, AL,期刊:Blood, 页码:4804-4812 , 文章类型: Article,,卷期:2009年114-23]
- Cyclic adenosine monophosphate response element binding (CREB)-binding protein (CBP) and p300 are multidomain transcriptional coactivators that help assemble large regulatory complexes at sites of active transcription. N...
- Sox7-sustained expression alters the balance between proliferation and differentiation of hematopoietic progenitors at the onset of blood specification
[作者:Gandillet, A; Serrano, AG; Pearson, S; Lie-A-Ling, M; Lacaud, G; Kouskoff, V,期刊:Blood, 页码:4813-4822 , 文章类型: Article,,卷期:2009年114-23]
- The molecular mechanisms that regulate the balance between proliferation and differentiation of precursors at the onset of hematopoiesis specification are poorly understood. By using a global gene expression profiling ap...
- Functionally distinct subsets of human NK cells and monocyte/DC-like cells identified by coexpression of CD56, CD7, and CD4
[作者:Milush, JM; Long, BR; Snyder-Cappione, JE; Cappione, AJ; York, VA; Ndhlovu, LC; Lanier, LL; Michaelsson, J; Nixon, DF,期刊:Blood, 页码:4823-4831 , 文章类型: Article,,卷期:2009年114-23]
- The lack of natural killer (NK) cell specific markers, as well as the overlap among several common surface antigens and functional properties, has obscured the delineation between NK cells and dendritic cells. Here, nove...
- In vivo intraclonal and interclonal kinetic heterogeneity in B-cell chronic lymphocytic leukemia
[作者:Calissano, C; Damle, RN; Hayes, G; Murphy, EJ; Hellerstein, MK; Moreno, C; Sison, C; Kaufman, MS; Kolitz, JE; Allen, SL; Rai, KR; Chiorazzi, N,期刊:Blood, 页码:4832-4842 , 文章类型: Article,,卷期:2009年114-23]
- Clonal evolution and outgrowth of cellular variants with additional chromosomal abnormalities are major causes of disease progression in chronic lymphocytic leukemia (CLL). Because new DNA lesions occur during S phase, p...
- Genetic variation in CXCR4 and risk of chronic lymphocytic leukemia
[作者:Crowther-Swanepoel, D; Qureshi, M; Dyer, MJS; Matutes, E; Dearden, C; Catovsky, D; Houlston, RS,期刊:Blood, 页码:4843-4846 , 文章类型: Article,,卷期:2009年114-23]
- A genome-wide linkage scan has provided evidence for a chronic lymphocytic leukemia (CLL) susceptibility locus at 2q21 to which the chemokine receptor CXCR4 gene maps. Recent data provide some evidence for common variati...
- Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML
[作者:Powell, JA; Thomas, D; Barry, EF; Kok, CH; McClure, BJ; Tsykin, A; To, LB; Brown, A; Lewis, ID; Herbert, K; Goodall, GJ; Speed, TP; Asou, N; Jacob, B; Osato, M; Haylock, DN; Nilsson, SK; D'Andrea, RJ; Lopez, AF; Guthridge, MA,期刊:Blood, 页码:4859-4870 , 文章类型: Article,,卷期:2009年114-23]
- Deregulated cell survival programs are a classic hallmark of cancer. We have previously identified a serine residue (Ser585) in the beta c subunit of the granulocyte-macrophage colony-stimulating factor receptor that sel...
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