- How I treat acute promyelocytic leukemia
[作者：Tallman, MS; Altman, JK,期刊：Blood, 页码：5126-5135 , 文章类型： Article，,卷期：2009年114-25]
- Acute promyelocytic leukemia is the first malignant disease highly curable with targeted therapy directed at a unique molecular abnormality. The characteristic bleeding diathesis is the most notorious manifestation of th...
- T-cell acute lymphoblastic leukemia in adults: clinical features, immunophenotype, cytogenetics, and outcome from the large randomized prospective trial (UKALL XII/ECOG 2993)
[作者：Marks, DI; Paietta, EM; Moorman, AV; Richards, SM; Buck, G; DeWald, G; Ferrando, A; Fielding, AK; Goldstone, AH; Ketterling, RP; Litzow, MR; Luger, SM; McMillan, AK; Mansour, MR; Rowe, JM; Tallman, MS; Lazarus, HM,期刊：Blood, 页码：5136-5145 , 文章类型： Article，,卷期：2009年114-25]
- The biology and outcome of adult T-cell acute lymphoblastic leukemia are poorly understood. We present here the clinical and biologic features of 356 patients treated uniformly on the prospective trial (UKALL XII/ECOG 29...
- The impact of prophylactic fresh-frozen plasma and cryoprecipitate on the incidence of central nervous system thrombosis and hemorrhage in children with acute lymphoblastic leukemia receiving asparaginase
[作者：Abbott, LS; Deevska, M; Fernandez, CV; Dix, D; Price, VE; Wang, H; Parker, L; Yhap, M; Fitzgerald, C; Barnard, DR; Berman, JN,期刊：Blood, 页码：5146-5151 , 文章类型： Article，,卷期：2009年114-25]
- Asparaginase (ASP) therapy is associated with depletion of antithrombin (AT) and fibrinogen (FG). Potential toxicities include central nervous system thrombosis (CNST) and hemorrhage. Historical practice at the Izaak Wal...
- In vivo delivery of a microRNA-regulated transgene induces antigen-specific regulatory T cells and promotes immunologic tolerance
[作者：Annoni, A; Brown, BD; Cantore, A; Sergi, LS; Naldini, L; Roncarolo, MG,期刊：Blood, 页码：5152-5161 , 文章类型： Article，,卷期：2009年114-25]
- We previously showed that incorporating target sequences for the hematopoietic-specific microRNA miR-142 into an antigen-encoding transgene prevents antigen expression in antigen-presenting cells (APCs). To determine whe...
- Differential requirement for Gata1 DNA binding and transactivation between primitive and definitive stages of hematopoiesis in zebrafish
[作者：Belele, CL; English, MA; Chahal, J; Burnetti, A; Finckbeiner, SM; Gibney, G; Kirby, M; Sood, R; Liu, PP,期刊：Blood, 页码：5162-5172 , 文章类型： Article，,卷期：2009年114-25]
- The transcription factor Gata1 is required for the development of erythrocytes and megakaryocytes. Previous studies with a complementation rescue approach showed that the zinc finger domains are required for both primiti...
- An in vitro model of differentiation of memory B cells into plasmablasts and plasma cells including detailed phenotypic and molecular characterization
[作者：Jourdan, M; Caraux, A; De Vos, J; Fiol, G; Larroque, M; Cognot, C; Bret, C; Duperray, C; Hose, D; Klein, B,期刊：Blood, 页码：5173-5181 , 文章类型： Article，,卷期：2009年114-25]
- Human plasma cells (PCs) and their precursors play an essential role in humoral immune response but are rare and difficult to harvest. We report the generation of human syndecan-1(+) and immunoglobulin secreting PCs star...
- Significant functional heterogeneity among KIR2DL1 alleles and a pivotal role of arginine(245)
[作者：Bari, R; Bell, T; Leung, WH; Vong, QP; Chan, WK; Das Gupta, N; Holladay, M; Rooney, B; Leung, W,期刊：Blood, 页码：5182-5190 , 文章类型： Article，,卷期：2009年114-25]
- Killer immunoglobulin-like receptors (KIRs) play an essential role in the regulation of natural killer cell functions. KIR genes are highly polymorphic in nature, showing both haplotypic and allelic variations among peop...
- Molecular and functional analysis of the stem cell compartment of chronic myelogenous leukemia reveals the presence of a CD34(-) cell population with intrinsic resistance to imatinib
[作者：Lemoli, RM; Salvestrini, V; Bianchi, E; Bertolini, F; Fogli, M; Amabile, M; Tafuri, A; Salati, S; Zini, R; Testoni, N; Rabascio, C; Rossi, L; Martin-Padura, I; Castagnetti, F; Marighetti, P; Martinelli, G; Baccarani, M; Ferrari, S; Manfredini, R,期刊：Blood, 页码：5191-5200 , 文章类型： Article，,卷期：2009年114-25]
- We show the molecular and functional characterization of a novel population of lineage-negative CD34-negative (Lin(-)CD34(-)) hematopoietic stem cells from chronic myelogenous leukemia (CML) patients at diagnosis. Molecu...
- Transforming growth factor-beta-induced protein (TGFBIp/beta ig-h3) activates platelets and promotes thrombogenesis
[作者：Kim, HJ; Kim, PK; Bae, SM; Son, HN; Thoudam, DS; Kim, JE; Lee, BH; Park, RW; Kim, IS,期刊：Blood, 页码：5206-5215 , 文章类型： Article，,卷期：2009年114-25]
- Transforming growth factor-beta-induced protein (TGFBIp)/beta ig-h3 is a 68-kDa extracellular matrix protein that is functionally associated with the adhesion, migration, proliferation, and differentiation of various cel...
- MICA-129 genotype, soluble MICA, and anti-MICA antibodies as biomarkers of chronic graft-versus-host disease
[作者：Boukouaci, W; Busson, M; de Latour, RP; Rocha, V; Suberbielle, C; Bengoufa, D; Dulphy, N; Haas, P; Scieux, C; Amroun, H; Gluckman, E; Krishnamoorthy, R; Toubert, A; Charron, D; Socie, G; Tamouza, R,期刊：Blood, 页码：5216-5224 , 文章类型： Article，,卷期：2009年114-25]
- The MHC class I-related chain A (MICA) molecules exist as membrane-bound and soluble isoforms and are encoded by a polymorphic gene. Their genetic and phenotype characteristics have been studied in various pathologic set...
- Evidence for a novel human-specific xeno-auto-antibody response against vascular endothelium
[作者：Pham, T; Gregg, CJ; Karp, F; Chow, R; Padler-Karavani, V; Cao, HZ; Chen, X; Witztum, JL; Varki, NM; Varki, A,期刊：Blood, 页码：5225-5235 , 文章类型： Article，,卷期：2009年114-25]
- Humans are genetically unable to synthesize the common mammalian sialic acid N-glycolylneuraminic acid (Neu5Gc). However, Neu5Gc can be metabolically incorporated and covalently expressed on cultured human cell surfaces....
- A CD44v6 peptide reveals a role of CD44 in VEGFR-2 signaling and angiogenesis
[作者：Tremmel, M; Matzke, A; Albrecht, I; Laib, AM; Olaku, V; Ballmer-Hofer, K; Christofori, G; Heroult, M; Augustin, HG; Ponta, H; Orian-Rousseau, V,期刊：Blood, 页码：5236-5244 , 文章类型： Article，,卷期：2009年114-25]
- A specific splice variant of the CD44 cell-surface protein family, CD44v6, has been shown to act as a coreceptor for the receptor tyrosine kinase c-Met on epithelial cells. Here we show that also on endothelial cells (EC...
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