- Mta3-NuRD complex is a master regulator for initiation of primitive hematopoiesis in vertebrate embryos
[作者:Li, X; Jia, SJ; Wang, SH; Wang, YM; Meng, AM,期刊:Blood, 页码:5464-5472 , 文章类型: Article,,卷期:2009年114-27]
- Metastasis-associated antigens 1/2/3 (Mta1/2/3) are components of nucleosome remodeling and deacetylase (NuRD) complexes and have been found to play roles in embryonic development and homeostasis. However, their function...
- Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders
[作者:Ye, ZH; Zhan, HC; Mali, P; Dowey, S; Williams, DM; Jang, YY; Dang, CV; Spivak, JL; Moliterno, AR; Cheng, LZ,期刊:Blood, 页码:5473-5480 , 文章类型: Article,,卷期:2009年114-27]
- Human induced pluripotent stem (iPS) cells derived from somatic cells hold promise to develop novel patient-specific cell therapies and research models for inherited and acquired diseases. We and others previously reprog...
- Epigenetic regulation of dendritic cell differentiation and function by oxidized phospholipids
[作者:Bluml, S; Zupkovitz, G; Kirchberger, S; Seyerl, M; Bochkov, VN; Stuhlmeier, K; Majdic, O; Zlabinger, GJ; Seiser, C; Stock, J,期刊:Blood, 页码:5481-5489 , 文章类型: Article,,卷期:2009年114-27]
- Dendritic cells (DCs) are the key cell type in the regulation of an adaptive immune response. Under inflammatory conditions monocytes can give rise to immunostimulatory DCs, depending on microenvironmental stimuli. Here ...
- Specific promoter methylation identifies different subgroups of MLL-rearranged infant acute lymphoblastic leukemia, influences clinical outcome, and provides therapeutic options
[作者:Stumpel, DJPM; Schneider, P; van Roon, EHJ; Boer, JM; de Lorenzo, P; Valsecchi, MG; de Menezes, RX; Pieters, R; Stam, RW,期刊:Blood, 页码:5490-5498 , 文章类型: Article,,卷期:2009年114-27]
- MLL-rearranged infant acute lymphoblastic leukemia (ALL) remains the most aggressive type of childhood leukemia, displaying a unique gene expression profile. Here we hypothesized that this characteristic gene expression ...
- Comprehensive genomic screens identify a role for PLZF-RAR alpha as a positive regulator of cell proliferation via direct regulation of c-MYC
[作者:Rice, KL; Hormaeche, I; Doulatov, S; Flatow, JM; Grimwade, D; Mills, KI; Leiva, M; Ablain, J; Ambardekar, C; McConnell, MJ; Dick, JE; Licht, JD,期刊:Blood, 页码:5499-5511 , 文章类型: Article,,卷期:2009年114-27]
- The t(11; 17)(q23;q21) translocation is associated with a retinoic acid (RA)-insensitive form of acute promyelocytic leukemia (APL), involving the production of reciprocal fusion proteins, promyelocytic leukemia zinc fin...
- Chemokine induction by all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia: triggering the differentiation syndrome
[作者:Luesink, M; Pennings, JLA; Wissink, WM; Linssen, PCM; Muus, P; Pfundt, R; de Witte, TJM; van der Reijden, BA; Jansen, JH,期刊:Blood, 页码:5512-5521 , 文章类型: Article,,卷期:2009年114-27]
- In acute promyelocytic leukemia (APL), differentiation therapy with all-trans retinoic acid (ATRA) and/or arsenic trioxide can induce a differentiation syndrome (DS) with massive pulmonary infiltration of differentiating...
- Migrating monocytes recruited to the spleen play an important role in control of blood stage malaria
[作者:Sponaas, AM; do Rosario, APF; Voisine, C; Mastelic, B; Thompson, J; Koernig, S; Jarra, W; Renia, L; Mauduit, M; Potocnik, AJ; Langhorne, J,期刊:Blood, 页码:5522-5531 , 文章类型: Article,,卷期:2009年114-27]
- Host responses controlling blood-stage malaria include both innate and acquired immune effector mechanisms. During Plasmodium chabaudi infection in mice, a population of CD11b(high)Ly6C(+) monocytes are generated in bone...
- The microtubule modulator RanBP10 plays a critical role in regulation of platelet discoid shape and degranulation
[作者:Kunert, S; Meyer, I; Fleischhauer, S; Wannack, M; Fiedler, J; Shivdasani, RA; Schulze, H,期刊:Blood, 页码:5532-5540 , 文章类型: Article,,卷期:2009年114-27]
- Terminally mature megakaryocytes undergo dramatic cellular reorganization to produce hundreds of virtually identical platelets. A hallmark feature of this process is the generation of an elaborate system of branched prot...
- Visualizing the von Willebrand factor/glycoprotein Ib-IX axis with a platelet-type von Willebrand disease mutation
[作者:Guerrero, JA; Kyei, M; Russell, S; Liu, JL; Gartner, TK; Storrie, B; Ware, J,期刊:Blood, 页码:5541-5546 , 文章类型: Article,,卷期:2009年114-27]
- Platelet-type von Willebrand disease (PT-VWD) is a bleeding disorder of the platelet glycoprotein Ib-IX/von Willebrand factor (VWF) axis caused by mutations in the glycoprotein Ib-IX receptor that lead to an increased af...
- EMMPRIN promotes angiogenesis through hypoxia-inducible factor-2 alpha-mediated regulation of soluble VEGF isoforms and their receptor VEGFR-2
[作者:Bougatef, F; Quemener, C; Kellouche, S; Naimi, B; Podgorniak, MP; Millot, G; Gabison, EE; Calvo, F; Dosquet, C; Lebbe, C; Menashi, S; Mourah, S,期刊:Blood, 页码:5547-5556 , 文章类型: Article,,卷期:2009年114-27]
- Extracellular matrix metalloproteinase inducer (EMMPRIN/CD147) is thought to promote tumor angiogenesis mostly through its protease-inducing function and more recently by its ability to increase tumor cell expression of ...
- Differential roles for ETS, CREB, and EGR binding sites in mediating VEGF receptor 1 expression in vivo
[作者:Jin, EJ; Liu, J; Suehiro, J; Yuan, L; Okada, Y; Nikolova-Krstevski, V; Yano, K; Janes, L; Beeler, D; Spokes, KC; Li, D; Regan, E; Shih, SC; Oettgen, P; Minami, T; Aird, WC,期刊:Blood, 页码:5557-5566 , 文章类型: Article,,卷期:2009年114-27]
- Vascular endothelial growth factor receptor 1 (VEGFR1) is a marker for endothelial-specific gene expression. We previously reported that the human VEGFR1 promoter (between -748 and +284) contains information for expressi...
- Birth order and outcome after HLA-identical sibling donor transplantation
[作者:Gratwohl, A; Doehler, B; Stern, M; Bucher, C; Passweg, J; Opelz, G,期刊:Blood, 页码:5569-5570 , 文章类型: Letter,,卷期:2009年114-27]
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- Neoplastic blood cells become pluripotent
[作者:Slukvin, II,期刊:Blood, 页码:5409-5410 , 文章类型: Editorial Material,,卷期:2009年114-27]
- The use of iPSCs in modeling for acquired blood disease. Bone marrow samples from patients with acquired blood diseases can be used to obtain mutation-free mesenchymal stem cells (MSCs) and CD34(+) cells or other types o...
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