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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共28条记录   Polymer delivery systems for site-specific genome editing [作者：McNeer, NA; Schleifman, EB; Glazer, PM; Saltzman, WM,期刊：Journal of controlled release, 页码：312-316 , 文章类型： Article; Proceedings Paper，,卷期：2011年155-2] Triplex-forming peptide nucleic acids (PNAs) can be used to coordinate the recombination of short 50-60 bp "donor DNA" fragments into genomic DNA, resulting in site-specific correction of genetic mutations or the introdu... Viral genome DNA/lipoplexes elicit in situ oncolytic viral replication and potent antitumor efficacy via systemic delivery [作者：Kwon, OJ; Kang, E; Kim, S; Yun, CO,期刊：Journal of controlled release, 页码：317-325 , 文章类型： Article; Proceedings Paper，,卷期：2011年155-2] Modifying the viral genome to express potent and cancer-selective therapeutic genes has enhanced the role of adenoviruses (Ads) in cancer molecular therapeutics. However, the efficacy of Ad systemic delivery in vivo is l... Targeted TFO delivery to hepatic stellate cells [作者：Yang, NN; Singh, S; Mahato, RI,期刊：Journal of controlled release, 页码：326-330 , 文章类型： Article; Proceedings Paper，,卷期：2011年155-2] Triplex-forming oligonucleotides (TFOs) represent an antigene approach for gene regulation through direct interaction with genomic DNA. While this strategy holds great promise owing to the fact that only two alleles need... Role of boronic acid moieties in poly(amido amine)s for gene delivery [作者：Piest, M; Engbersen, JFJ,期刊：Journal of controlled release, 页码：331-340 , 文章类型： Article; Proceedings Paper，,卷期：2011年155-2] The effects of the presence of two different types of phenylboronic acids as side groups in disulfide-containing poly(amido amine)s (SS-PAA) were investigated in the application of these polymers as gene delivery vectors... Proceedings of the Fifthteenth International Symposium on Recent Advances in Drug Delivery Systems Preface [作者：Park, K; Bae, YH; Grainger, DW,期刊：Journal of controlled release, 页码：113-114 , 文章类型： Editorial Material，,卷期：2011年155-2] Biomaterials to gene delivery [作者：Kim, SW,期刊：Journal of controlled release, 页码：116-118 , 文章类型： Article; Proceedings Paper，,卷期：2011年155-2] It has been over 40 years since I started biomaterials research. This article is a short summary of past research in my laboratory. (C) 2011 Elsevier B.V. All rights reserved. Advanced molecular design of biopolymers for transmucosal and intracellular delivery of chemotherapeutic agents and biological therapeutics [作者：Liechty, WB; Caldorera-Moore, M; Phillips, MA; Schoener, C; Peppas, NA,期刊：Journal of controlled release, 页码：119-127 , 文章类型： Article; Proceedings Paper，,卷期：2011年155-2] Hydrogels have been instrumental in the development of polymeric systems for controlled release of therapeutic agents. These materials are attractive for transmucosal and intracellular drug delivery because of their faci... Cell-penetrating peptides can confer biological function: Regulation of inflammatory cytokines in human monocytes by MK2 inhibitor peptides [作者：Brugnano, JL; Chan, BK; Seal, BL; Panitch, A,期刊：Journal of controlled release, 页码：128-133 , 文章类型： Article; Proceedings Paper，,卷期：2011年155-2] Cell-penetrating peptides have been used as a method of delivering biologically active peptide for over two decades. In this paper, we covalently attached four different cell-penetrating peptides to a peptide that inhibi... Cellular uptake of cyclotide MCoTI-I follows multiple endocytic pathways [作者：Contreras, J; Elnagar, AYO; Hamm-Alvarez, SF; Camarero, JA,期刊：Journal of controlled release, 页码：134-143 , 文章类型： Article; Proceedings Paper，,卷期：2011年155-2] Cyclotides are plant-derived proteins that naturally exhibit various biological activities and whose unique cyclic structure makes them remarkably stable and resistant to denaturation or degradation. These attributes, am... In vivo tumor targeting by a NGR-decorated micelle of a recombinant diblock copolypeptide [作者：Simnick, AJ; Amiram, M; Liu, WG; Hanna, G; Dewhirst, MW; Kontos, CD; Chilkoti, A,期刊：Journal of controlled release, 页码：144-151 , 文章类型： Article; Proceedings Paper，,卷期：2011年155-2] Antivascular targeting is a promising strategy for tumor therapy. This strategy has the potential to overcome many of the transport barriers associated with targeting tumor cells in solid tumors, because the tumor vascul... Development of MRI/NIRF 'activatable' multimodal imaging probe based on iron oxide nanoparticles [作者：Cha, EJ; Jang, ES; Sun, IC; Lee, IJ; Ko, JH; Kim, YI; Kwon, IC; Kim, K; Ahn, CH,期刊：Journal of controlled release, 页码：152-158 , 文章类型： Article; Proceedings Paper，,卷期：2011年155-2] A fabrication method of Cy5.5-MMP substrate and PEG conjugated iron oxide nanoparticles with thin silica coating (PCM-CS) and its potential as an 'activatable' dual imaging probe for tumor imaging is described in this re... Design of multi-drug release coatings targeting infection and inflammation [作者：Shukla, A; Fuller, RC; Hammond, PT,期刊：Journal of controlled release, 页码：159-166 , 文章类型： Article; Proceedings Paper，,卷期：2011年155-2] Although infection and inflammation commonly coexist, there is a paucity of appropriate methods for concurrent localized delivery of antibiotics and non-steroidal anti-inflammatory drugs (NSAIDs) at appropriate concentra... RAFT-synthesized graft copolymers that enhance pH-dependent membrane destabilization and protein circulation times [作者：Crownover, E; Duvall, CL; Convertine, A; Hoffman, AS; Stayton, PS,期刊：Journal of controlled release, 页码：167-174 , 文章类型： Article; Proceedings Paper，,卷期：2011年155-2] Here we describe a new graft copolymer architecture of poly(propylacrylic acid) (polyPAA) that displays potent pH-dependent, membrane-destabilizing activity and in addition is shown to enhance protein blood circulation k... Thermo-targeted drug delivery of geldanamycin to hyperthermic tumor margins with diblock elastin-based biopolymers [作者：Chen, Y; Youn, P; Furgeson, DY,期刊：Journal of controlled release, 页码：175-183 , 文章类型： Article; Proceedings Paper，,卷期：2011年155-2] The tumor margins are the barrier to hepatocellular carcinoma (HCC) eradication for tumors>3 cm. Indeed, inadequately treated tumor margins commonly result in local and regional HCC recurrence with increased size and mas... An injectable synthetic immune-priming center mediates efficient T-cell class switching and T-helper 1 response against B cell lymphoma [作者：Singh, A; Qin, H; Fernandez, I; Wei, JS; Lin, J; Kwak, LW; Roy, K,期刊：Journal of controlled release, 页码：184-192 , 文章类型： Article; Proceedings Paper，,卷期：2011年155-2] Patients with malignant non-Hodgkin's lymphomas (NHL) of B-cell lineages relapse despite initial anti-tumor response to chemotherapy or antibody treatments. Failure to eliminate the tumor is often because of inadequate p... Hyaluronic acid-based clinical biomaterials derived for cell and molecule delivery in regenerative medicine [作者：Prestwich, GD,期刊：Journal of controlled release, 页码：193-199 , 文章类型： Article; Proceedings Paper，,卷期：2011年155-2] The development of injectable and biocompatible vehicles for delivery, retention, growth, and differentiation of stem cells is of paramount importance for regenerative medicine. For cell therapy and the development of cl...