- Latest advances on regiospecific microwave-assisted synthesis of novel purine derivatives as antitumor agents
[作者:Conejo-Garcia, A; Gallo, MA; Espinosa, A; Campos, JM,期刊:Expert Opinion on Therapeutic Patents, 页码:211-222 , 文章类型: Article,,卷期:2008年18-2]
Background: Breast cancer, a leading cause of mortality in women, warrants the development of biological evaluation of new anticancer agents. Objective: A novel series of (RS)-6-substituted-7 or 9-(2,3-dihydro-5H-1,4-...
- Dihydrofolate reductase inhibitors: developments in antiparasitic chemotherapy
[作者:Bolstad, DB; Bolstad, ESD; Wright, DL; Anderson, AC,期刊:Expert Opinion on Therapeutic Patents, 页码:143-157 , 文章类型: Review,,卷期:2008年18-2]
Background: Infections caused by parasitic protozoa present a growing health concern, particularly in developing parts of the world. Although malaria is clearly the most well-known and deadly of these diseases, infect...
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