- Interaction of Hypoxia-Inducible Factor-1 alpha and Notch Signaling Regulates Medulloblastoma Precursor Proliferation and Fate
[作者：Pistollato, F; Rampazzo, E; Persano, L; Abbadi, S; Frasson, C; Denaro, L; D'Avella, D; Panchision, DM; Della Puppa, A; Scienza, R; Basso, G,期刊：Stem Cells, 页码：1918-1929 , 文章类型： Article，,卷期：2010年28-11]
- Medulloblastoma (MDB) is the most common brain malignancy of childhood. It is currently thought that MDB arises from aberrantly functioning stem cells in the cerebellum that fail to maintain proper control of self-renewa...
- Crosstalk Between the PI3K/mTOR and MEK/ERK Pathways Involved in the Maintenance of Self-Renewal and Tumorigenicity of Glioblastoma Stem-Like Cells
[作者：Sunayama, J; Matsuda, KI; Sato, A; Tachibana, K; Suzuki, K; Narita, Y; Shibui, S; Sakurada, K; Kayama, T; Tomiyama, A; Kitanaka, C,期刊：Stem Cells, 页码：1930-1939 , 文章类型： Article，,卷期：2010年28-11]
- The molecular signaling pathways orchestrating the biology of cancer stem-like cells (CSLCs), including glioblastoma, remain to be elucidated. We investigated in this study the role of the MEK/extracellular signal-regula...
- Neuronatin Promotes Neural Lineage in ESCs Via Ca2+ Signaling
[作者：Lin, HH; Bell, E; Uwanogho, D; Perfect, LW; Noristani, H; Bates, TJD; Snetkov, V; Price, J; Sun, YM,期刊：Stem Cells, 页码：1950-1960 , 文章类型： Article，,卷期：2010年28-11]
- Neural induction is the first step in the formation of the vertebrate central nervous system. The emerging consensus of the mechanisms underling neural induction is the combined influences from inhibiting bone morphogene...
- The Pluripotency Regulator Zic3 Is a Direct Activator of the Nanog Promoter in ESCs
[作者：Lim, LS; Hong, FH; Kunarso, G; Stanton, LW,期刊：Stem Cells, 页码：1961-1969 , 文章类型： Article，,卷期：2010年28-11]
- The transcription factor Zic3 is required for maintenance of ESC pluripotency. By genome-wide chromatin immunoprecipitation (ChIP-chip) in ESCs, we have identified 379 direct Zic3 targets, many of which are functionally ...
- Opposing Putative Roles for Canonical and Noncanonical NF kappa B Signaling on the Survival, Proliferation, and Differentiation Potential of Human Embryonic Stem Cells
[作者：Yang, CB; Atkinson, SP; Vilella, F; Lloret, M; Armstrong, L; Mann, DA; Lako, M,期刊：Stem Cells, 页码：1970-1980 , 文章类型： Article，,卷期：2010年28-11]
- The canonical and noncanonical NF kappa B signaling pathways regulate a variety of cellular activities; however, their functions in human embryonic stem cells (hESCs) have not been fully investigated. Expression studies ...
- Long-Term Survival of Photoreceptors Transplanted into the Adult Murine Neural Retina Requires Immune Modulation
[作者：West, EL; Pearson, RA; Barker, SE; Luhmann, UFO; Maclaren, RE; Barber, AC; Duran, Y; Smith, AJ; Sowden, JC; Ali, RR,期刊：Stem Cells, 页码：1997-2007 , 文章类型： Article，,卷期：2010年28-11]
- Stem cell therapy presents an opportunity to replace photoreceptors that are lost as a result of inherited and age-related degenerative disease. We have previously shown that murine postmitotic rod photoreceptor precurso...
- Functional Control of Transplantable Human ESC-Derived Neurons via Optogenetic Targeting
[作者：Weick, JP; Johnson, MA; Skroch, SP; Williams, JC; Deisseroth, K; Zhang, SC,期刊：Stem Cells, 页码：2008-2016 , 文章类型： Article，,卷期：2010年28-11]
- Current methods to examine and regulate the functional integration and plasticity of human ESC (hESC)-derived neurons are cumbersome and technically challenging. Here, we engineered hESCs and their derivatives to express...
- Expression and Proliferation-Promoting Role of Diversin in the Neuronally Committed Precursor Cells Migrating in the Adult Mouse Brain
[作者：Ikeda, M; Hirota, Y; Sakaguchi, M; Yamada, O; Kida, YS; Ogura, T; Otsuka, T; Okano, H; Sawamoto, K,期刊：Stem Cells, 页码：2017-2026 , 文章类型： Article，,卷期：2010年28-11]
- The subventricular zone (SVZ) is the largest neurogenic region in the adult rodent brain. In the adult SVZ, unlike in the embryonic brain, neuronally committed precursor cells (neuroblasts) maintain their proliferative a...
- Convergent Genesis of an Adult Neural Crest-Like Dermal Stem Cell from Distinct Developmental Origins
[作者：Jinno, H; Morozova, O; Jones, KL; Biernaskie, JA; Paris, M; Hosokawa, R; Rudnicki, MA; Chai, Y; Rossi, F; Marra, MA; Miller, FD,期刊：Stem Cells, 页码：2027-2040 , 文章类型： Article，,卷期：2010年28-11]
- Skin-derived precursors (SKPs) are multipotent dermal stem cells that reside within a hair follicle niche and that share properties with embryonic neural crest precursors. Here, we have asked whether SKPs and their endog...
- Bidirectional Regulation of Neurogenesis by Neuronal Nitric Oxide Synthase Derived from Neurons and Neural Stem Cells
[作者：Luo, CX; Jin, X; Cao, CC; Zhu, MM; Wang, B; Chang, L; Zhou, QG; Wu, HY; Zhu, DY,期刊：Stem Cells, 页码：2041-2052 , 文章类型： Article，,卷期：2010年28-11]
- It has been demonstrated that neuronal nitric oxide synthase (nNOS) negatively regulates adult neurogenesis. However, the cellular and molecular mechanisms underlying are poorly understood. Here, we show that nNOS from n...
- Adenomatous Polyposis Coli Is Essential for Both Neuronal Differentiation and Maintenance of Adult Neural Stem Cells in Subventricular Zone and Hippocampus
[作者：Imura, T; Wang, XH; Noda, T; Sofroniew, MV; Fushiki, S,期刊：Stem Cells, 页码：2053-2064 , 文章类型： Article，,卷期：2010年28-11]
- The tumor suppressor adenomatous polyposis coli (APC) is a multifunctional protein that not only inhibits the Wnt signaling pathway by promoting the degradation of beta-catenin but also controls cell polarity, motility, ...
- Adipose Tissue as a Dedicated Reservoir of Functional Mast Cell Progenitors
[作者：Poglio, S; De Toni-Costes, F; Arnaud, E; Laharrague, P; Espinosa, E; Casteilla, L; Cousin, B,期刊：Stem Cells, 页码：2065-2072 , 文章类型： Article，,卷期：2010年28-11]
- White adipose tissue (WAT) is a heterogeneous tissue, found in various locations throughout the body, containing mature adipocytes and the stroma-vascular fraction (SVF). The SVF includes a large proportion of immune hem...
|