- Permanently Blocked Stem Cells Derived From Breast Cancer Cell Lines
[作者:Sajithlal, GB; Rothermund, K; Zhang, F; Dabbs, DJ; Latimer, JJ; Grant, SG; Prochownik, EV,期刊:Stem Cells, 页码:1008-1018 , 文章类型: Article,,卷期:2010年28-6]
- Cancer stem cells (CSCs) are thought to be resistant to standard chemotherapeutic drugs and the inimical conditions of the tumor microenvironment. Obtaining CSCs in sufficient quantities and maintaining their undifferent...
- Inhibition of Notch Signaling in Glioblastoma Targets Cancer Stem Cells via an Endothelial Cell Intermediate
[作者:Hovinga, KE; Shimizu, F; Wang, R; Panagiotakos, G; Van Der Heijden, M; Moayedpardazi, H; Correia, AS; Soulet, D; Major, T; Menon, J; Tabar, V,期刊:Stem Cells, 页码:1019-1029 , 文章类型: Article,,卷期:2010年28-6]
- Glioblastoma multiforme (GBM) is a highly heterogeneous malignant tumor. Recent data suggests the presence of a hierarchical organization within the GBM cell population that involves cancer cells with stem-like behavior,...
- A Role for Borg5 During Trophectoderm Differentiation
[作者:Vong, QP; Liu, ZH; Yoo, JG; Chen, R; Xie, W; Sharov, AA; Fan, CM; Liu, CY; Ko, MSH; Zheng, YX,期刊:Stem Cells, 页码:1030-1038 , 文章类型: Article,,卷期:2010年28-6]
- Stem cell differentiation is accompanied by a gradual cellular morphogenesis and transcriptional changes. Identification of morphological regulators that control cell behavior during differentiation could shed light on h...
- Endothelial Progenitor Cells Homing and Renal Repair in Experimental Renovascular Disease
[作者:Chade, AR; Zhu, XY; Krier, JD; Jordan, KL; Textor, SC; Grande, JP; Lerman, A; Lerman, LO,期刊:Stem Cells, 页码:1039-1047 , 文章类型: Article,,卷期:2010年28-6]
- Tissue injury triggers reparative processes that often involve endothelial progenitor cells (EPCs) recruitment. We hypothesized that atherosclerotic renal artery stenosis (ARAS) activates homing signals that would be det...
- Adult Ciliary Epithelial Cells, Previously Identified as Retinal Stem Cells with Potential for Retinal Repair, Fail to Differentiate into New Rod Photoreceptors
[作者:Gualdoni, S; Baron, M; Lakowski, J; Decembrini, S; Smith, AJ; Pearson, RA; Ali, RR; Sowden, JC,期刊:Stem Cells, 页码:1048-1059 , 文章类型: Article,,卷期:2010年28-6]
- The ciliary margin in lower vertebrates is a site of continual retinal neurogenesis and a stem cell niche. By contrast, the human eye ceases retinal neuron production before birth and loss of photoreceptors during life i...
- MicroRNA miR-137 Regulates Neuronal Maturation by Targeting Ubiquitin Ligase Mind Bomb-1
[作者:Smrt, RD; Szulwach, KE; Pfeiffer, RL; Li, XK; Guo, WX; Pathania, M; Teng, ZQ; Luo, YP; Peng, JM; Bordey, A; Jin, P; Zhao, XY,期刊:Stem Cells, 页码:1060-1070 , 文章类型: Article,,卷期:2010年28-6]
- The maturation of young neurons is regulated by complex mechanisms and dysregulation of this process is frequently found in neurodevepmental disorders. MicroRNAs have been implicated in several steps of neuronal maturati...
- Leptin Functions Peripherally to Regulate Differentiation of Mesenchymal Progenitor Cells
[作者:Scheller, EL; Song, JH; Dishowitz, MI; Soki, FN; Hankenson, KD; Krebsbach, PH,期刊:Stem Cells, 页码:1071-1080 , 文章类型: Article,,卷期:2010年28-6]
- Leptin functions through a well-documented central neuroendocrine pathway to regulate bone mass. However, the ability of leptin to modulate bone mass through a peripheral mechanism has been debated due to conflicting in ...
- The CD10 Enzyme Is a Key Player to Identify and Regulate Human Mammary Stem Cells
[作者:Bachelard-Cascales, E; Chapellier, M; Delay, E; Pochon, G; Voeltzel, T; Puisieux, A; de Fromentel, CC; Maguer-Satta, V,期刊:Stem Cells, 页码:1081-1088 , 文章类型: Article,,卷期:2010年28-6]
- The major components of the mammary ductal tree are an inner layer of luminal cells, an outer layer of myoepithelial cells, and a basement membrane that separates the ducts from the underlying stroma. Cells in the outer ...
- A Long-Term Follow-Up Study of Intravenous Autologous Mesenchymal Stem Cell Transplantation in Patients With Ischemic Stroke
[作者:Lee, JS; Hong, JM; Moon, GJ; Lee, PH; Ahn, YH; Bang, OY,期刊:Stem Cells, 页码:1099-1106 , 文章类型: Article,,卷期:2010年28-6]
- We previously evaluated the short-term follow-up preliminary data of mesenchymal stem cells (MSCs) transplantation in patients with ischemic stroke. The present study was conducted to evaluate the long-term safety and ef...
- An Inducible Caspase 9 Suicide Gene to Improve the Safety of Mesenchymal Stromal Cell Therapies
[作者:Ramos, CA; Asgari, Z; Liu, EL; Yvon, E; Heslop, HE; Rooney, CM; Brenner, MK; Dotti, G,期刊:Stem Cells, 页码:1107-1115 , 文章类型: Article,,卷期:2010年28-6]
- Mesenchymal stromal cells (MSCs) have been infused in hundreds of patients to date, with minimal reported side effects. However, follow-up is limited and long-term side effects are unknown. Because several animal models ...
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