- Pleiotropic regulation of macrophage polarization and tumorigenesis by formyl peptide receptor-2
[作者:Li, Y; Cai, L; Wang, H; Wu, P; Gu, W; Chen, Y; Hao, H; Tang, K; Yi, P; Liu, M; Miao, S; Ye, D,期刊:Oncogene, 页码:3887-3899 , 文章类型: Article,,卷期:2011年30-36]
- Cancer cells recruit monocytes, macrophages and other inflammatory cells by producing abundant chemo-attractants and growth factors, such as macrophage colony-stimulating factor (M-CSF/CSF-1) and monocyte chemoattractant...
- Interstitial lung disease induced by gefitinib and Toll-like receptor ligands is mediated by Fra-1
[作者:Takada, Y; Gresh, L; Bozec, A; Ikeda, E; Kamiya, K; Watanabe, M; Kobayashi, K; Asano, K; Toyama, Y; Wagner, EF; Matsuo, K,期刊:Oncogene, 页码:3821-3832 , 文章类型: Article,,卷期:2011年30-36]
- The role of the AP-1 transcription factor Fra-1 (encoded by Fosl1) in inflammatory responses associated with lung disease is largely unknown. Here, we show that Fra-1 overexpression in mice reduced proinflammatory cytoki...
- NANOG promotes cancer stem cell characteristics and prostate cancer resistance to androgen deprivation
[作者:Jeter, CR; Liu, B; Liu, X; Chen, X; Liu, C; Calhoun-Davis, T; Repass, J; Zaehres, H; Shen, JJ; Tang, DG,期刊:Oncogene, 页码:3833-3845 , 文章类型: Article,,卷期:2011年30-36]
- Cancer cell molecular mimicry of stem cells (SC) imbues neoplastic cells with enhanced proliferative and renewal capacities. In support, numerous mediators of SC self-renewal have been evinced to show oncogenic potential...
- ARF1 controls proliferation of breast cancer cells by regulating the retinoblastoma protein
[作者:Boulay, PL; Schlienger, S; Lewis-Saravalli, S; Vitale, N; Ferbeyre, G; Claing, A,期刊:Oncogene, 页码:3846-3861 , 文章类型: Article,,卷期:2011年30-36]
- The ADP-ribosylation factors (ARFs) 1 and 6 are small GTP-binding proteins, highly expressed and activated in several breast cancer cell lines and are associated with enhanced migration and invasiveness. In this study, w...
- Loss of AF6/afadin, a marker of poor outcome in breast cancer, induces cell migration, invasiveness and tumor growth
[作者:Fournier, G; Cabaud, O; Josselin, E; Chaix, A; Adelaide, J; Isnardon, D; Restouin, A; Castellano, R; Dubreuil, P; Chaffanet, M; Birnbaum, D; Lopez, M,期刊:Oncogene, 页码:3862-3874 , 文章类型: Article,,卷期:2011年30-36]
- Afadin/AF6, an F-actin-binding protein, is ubiquitously expressed in epithelia and has a key role during development, through its regulatory role in cell-cell junction organization. Afadin loss of expression in 15% of br...
- Upregulation of miR-27a contributes to the malignant transformation of human bronchial epithelial cells induced by SV40 small T antigen
[作者:Wang, Q; Li, DC; Li, ZF; Liu, CX; Xiao, YM; Zhang, B; Li, XD; Zhao, J; Chen, LP; Xing, XM; Tang, SF; Lin, YC; Lai, YD; Yang, P; Zeng, JL; Xiao, Q; Zeng, XW; Lin, ZN; Zhuang, ZX; Zhuang, SM; Chen, W,期刊:Oncogene, 页码:3875-3886 , 文章类型: Article,,卷期:2011年30-36]
- The introduction of the Simian virus 40 (SV40) early region, the telomerase catalytic subunit (hTERT) and an oncogenic allele of H-Ras directly transforms primary human cells. SV40 small T antigen (ST), which forms a com...
- Wwox inactivation enhances mammary tumorigenesis
[作者:Abdeen, SK; Salah, Z; Maly, B; Smith, Y; Tufail, R; Abu-Odeh, M; Zanesi, N; Croce, CM; Nawaz, Z; Aqeilan, RI,期刊:Oncogene, 页码:3900-3906 , 文章类型: Article,,卷期:2011年30-36]
- Breast cancer is the leading cause of cancer-related death in women worldwide. Expression of the WWOX tumor suppressor is absent or reduced in a large proportion of breast tumors suggesting that loss of WWOX may contribu...
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