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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共7条记录   Insulin-like growth factor binding protein 5 suppresses tumor growth and metastasis of human osteosarcoma [作者：Su, Y; Wagner, ER; Luo, Q; Huang, J; Chen, L; He, BC; Zuo, GW; Shi, Q; Zhang, BQ; Zhu, G; Bi, Y; Luo, J; Luo, X; Kim, SH; Shen, J; Rastegar, F; Huang, E; Gao, Y; Gao, JL; Yang, K; Wietholt, C; Li, M; Qin, J; Haydon, RC; He, TC; Luu, HH,期刊：Oncogene, 页码：3907-3917 , 文章类型： Article，,卷期：2011年30-37] Osteosarcoma (OS) is the most common primary malignancy of bone. There is a critical need to identify the events that lead to the poorly understood mechanism of OS development and metastasis. The goal of this investigati... BH3 mimetics activate multiple pro-autophagic pathways [作者：Malik, SA; Orhon, I; Morselli, E; Criollo, A; Shen, S; Marino, G; BenYounes, A; Benit, P; Rustin, P; Maiuri, MC; Kroemer, G,期刊：Oncogene, 页码：3918-3929 , 文章类型： Article，,卷期：2011年30-37] The BH3 mimetic ABT737 induces autophagy by competitively disrupting the inhibitory interaction between the BH3 domain of Beclin 1 and the anti-apoptotic proteins Bcl-2 and Bcl-XL, thereby stimulating the Beclin 1-depend... Inhibition of p53 represses E-cadherin expression by increasing DNA methyltransferase-1 and promoter methylation in serous borderline ovarian tumor cells [作者：Cheng, JC; Auersperg, N; Leung, PCK,期刊：Oncogene, 页码：3930-3942 , 文章类型： Article，,卷期：2011年30-37] The mechanisms underlying the progression of noninvasive serous borderline ovarian tumors (SBOT) to low-grade invasive carcinomas are poorly understood. We recently showed that inhibition of p53 induces SBOT invasion by ... Phosphorylation of histone H3 serine 28 modulates RNA polymerase III-dependent transcription [作者：Zhang, Q; Zhong, Q; Evans, AG; Levy, D; Zhong, S,期刊：Oncogene, 页码：3943-3952 , 文章类型： Article，,卷期：2011年30-37] Deregulation of RNA polymerase III (Pol III) transcription enhances cellular tRNAs and 5S rRNA production, leading to an increase in translational capacity to promote cell proliferation, transformation and tumor formatio... Nodal enhances the activity of FoxO3a and its synergistic interaction with Smads to regulate cyclin G2 transcription in ovarian cancer cells [作者：Fu, G; Peng, C,期刊：Oncogene, 页码：3953-3966 , 文章类型： Article，,卷期：2011年30-37] Nodal, a member of the transforming growth factor-beta superfamily, has been recently shown to suppress cell proliferation and to stimulate the expression of cyclin G2 (CCNG2) in human epithelial ovarian cancer cells. Ho... SPG20, a novel biomarker for early detection of colorectal cancer, encodes a regulator of cytokinesis [作者：Lind, GE; Raiborg, C; Danielsen, SA; Rognum, TO; Thiis-Evensen, E; Hoff, G; Nesbakken, A; Stenmark, H; Lothe, RA,期刊：Oncogene, 页码：3967-3978 , 文章类型： Article，,卷期：2011年30-37] Colorectal cancer is a common disease with high mortality. Suitable biomarkers for detection of tumors at an early curable stage would significantly improve patient survival. Here, we show that the SPG20 (spastic paraple... E2F1 suppresses Wnt/beta-catenin activity through transactivation of beta-catenin interacting protein ICAT [作者：Wu, Z; Zheng, S; Li, Z; Tan, J; Yu, Q,期刊：Oncogene, 页码：3979-3984 , 文章类型： Article，,卷期：2011年30-37] Deregulation of the pRb/E2F or Wnt/beta-catenin pathway occurs frequently in human cancers, which is often associated with inappropriate cell proliferation. Although the oncogenic roles of pRb/E2F1 and Wnt/beta-catenin p...