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  • Regulation of transcription factor E2F3a and its clinical relevance in ovarian cancer
    [作者:Reimer, D; Hubalek, M; Kiefel, H; Riedle, S; Skvortsov, S; Erdel, M; Hofstetter, G; Concin, N; Fiegl, H; Muller-Holzner, E; Marth, C; Altevogt, P; Zeimet, AG,期刊:Oncogene, 页码:4038-4049 , 文章类型: Article,,卷期:2011年30-38]
  • Recently we showed an integral epidermal growth factor receptor (EGFR)-E2F3a signaling path, in which E2F3a was found to be essential in EGFR-mediated proliferation in ovarian cancer cells. The present work evaluates the...
  • Further activation of FLT3 mutants by FLT3 ligand
    [作者:Zheng, R; Bailey, E; Nguyen, B; Yang, X; Piloto, O; Levis, M; Small, D,期刊:Oncogene, 页码:4004-4014 , 文章类型: Article,,卷期:2011年30-38]
  • Somatic mutations of FLT3 involving internal tandem duplication (ITD) of the juxtamembrane domain or point mutations in the tyrosine kinase domain (TKD) appear to activate FLT3 in a FLT3 ligand (FL)-independent manner. T...
  • Identification of AFAP1L1 as a prognostic marker for spindle cell sarcomas
    [作者:Furu, M; Kajita, Y; Nagayama, S; Ishibe, T; Shima, Y; Nishijo, K; Uejima, D; Takahashi, R; Aoyama, T; Nakayama, T; Nakamura, T; Nakashima, Y; Ikegawa, M; Imoto, S; Katagiri, T; Nakamura, Y; Toguchida, J,期刊:Oncogene, 页码:4015-4025 , 文章类型: Article,,卷期:2011年30-38]
  • Spindle cell sarcomas consist of tumors with different biological features, of which distant metastasis is the most ominous sign for a poor prognosis. However, metastasis is difficult to predict on the basis of current h...