- Integrin-linked kinase: Not so 'pseudo' after all
[作者：Hannigan, GE; McDonald, PC; Walsh, MP; Dedhar, S,期刊：Oncogene, 页码：4375-4385 , 文章类型： Review，,卷期：2011年30-43]
- Integrin-linked kinase (ILK) is a highly evolutionarily conserved intracellular protein that was originally identified as an integrin-interacting protein, and extensive genetic and biochemical studies have shown that ILK...
- miR-135a contributes to paclitaxel resistance in tumor cells both in vitro and in vivo
[作者：Holleman, A; Chung, I; Olsen, RR; Kwak, B; Mizokami, A; Saijo, N; Parissenti, A; Duan, Z; Voest, EE; Zetter, BR,期刊：Oncogene, 页码：4386-4398 , 文章类型： Article，,卷期：2011年30-43]
- Cancer cell resistance to paclitaxel continues to be a major clinical problem. In this study, we utilized microRNA (miRNA) arrays to screen for differentially expressed miRNAs in paclitaxel-resistant cell lines establish...
- Keratin 6a marks mammary bipotential progenitor cells that can give rise to a unique tumor model resembling human normal-like breast cancer
[作者：Bu, W; Chen, J; Morrison, GD; Huang, S; Creighton, CJ; Huang, J; Chamness, GC; Hilsenbeck, SG; Roop, DR; Leavitt, AD; Li, Y,期刊：Oncogene, 页码：4399-4409 , 文章类型： Article，,卷期：2011年30-43]
- Progenitor cells are considered an important cell of origin of human malignancies. However, there has not been any single gene that can define mammary bipotential progenitor cells, and as such it has not been possible to...
- HAb18G/CD147 promotes epithelial-mesenchymal transition through TGF-beta signaling and is transcriptionally regulated by Slug
[作者：Wu, J; Ru, NY; Zhang, Y; Li, Y; Wei, D; Ren, Z; Huang, XF; Chen, ZN; Bian, H,期刊：Oncogene, 页码：4410-4427 , 文章类型： Article，,卷期：2011年30-43]
- Epithelial-mesenchymal transition (EMT) induced by transforming growth factor-beta (TGF-beta) is implicated in hepatocarcinogenesis and hepatocellular carcinoma (HCC) metastasis. HAb18G/CD147, which belongs to the CD147 ...
- Uncommitted precursor cells might contribute to increased incidence of embryonal rhabdomyosarcoma in heterozygous Patched1-mutant mice
[作者：Nitzki, F; Zibat, A; Frommhold, A; Schneider, A; Schulz-Schaeffer, W; Braun, T; Hahn, H,期刊：Oncogene, 页码：4428-4436 , 文章类型： Article，,卷期：2011年30-43]
- Embryonal rhabdomyosarcoma (ERMS) is a tumor of the skeletal muscle in children and is frequently initiated by heterozygous germline mutations in the Hedgehog (Hh) receptor Patched1 (Ptch), both in humans and mice. Using...
- FZD7 has a critical role in cell proliferation in triple negative breast cancer
[作者：Yang, L; Wu, X; Wang, Y; Zhang, K; Wu, J; Yuan, YC; Deng, X; Chen, L; Kim, CCH; Lau, S; Somlo, G; Yen, Y,期刊：Oncogene, 页码：4437-4446 , 文章类型： Article，,卷期：2011年30-43]
- Breast cancer is genetically and clinically heterogeneous. Triple negative breast cancer (TNBC) is a subtype of breast cancer that is usually associated with poor outcome and lack of benefit from targeted therapy. We use...
- Targeting fibroblast growth factor receptor 3 enhances radiosensitivity in human squamous cancer cells
[作者：Uzawa, K; Ishigami, T; Fushimi, K; Kawata, T; Shinozuka, K; Kasamatsu, A; Sakamoto, Y; Ogawara, K; Shiiba, M; Bukawa, H; Ito, H; Tanzawa, H,期刊：Oncogene, 页码：4447-4452 , 文章类型： Article，,卷期：2011年30-43]
- Conventional therapies including radiation therapy cannot cure squamous cell carcinoma (SCC), and new treatments are clearly required. Our recent studies have shown that SCC cell lines exhibiting radioresistance show sig...
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