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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共9条记录   Shikonin and its analogs inhibit cancer cell glycolysis by targeting tumor pyruvate kinase-M2 [作者：Chen, J; Xie, J; Jiang, Z; Wang, B; Wang, Y; Hu, X,期刊：Oncogene, 页码：4297-4306 , 文章类型： Article，,卷期：2011年30-42] We recently reported that shikonin and its analogs were a class of necroptotic inducers that could bypass cancer drug resistance. However, the molecular targets of shikonin are not known. Here, we showed that shikonin an... Akt1 deficiency delays tumor progression, vascular invasion, and distant metastasis in a murine model of thyroid cancer [作者：Saji, M; Narahara, K; McCarty, SK; Vasko, VV; La Perle, KM; Porter, K; Jarjoura, D; Lu, C; Cheng, SY; Ringel, MD,期刊：Oncogene, 页码：4307-4315 , 文章类型： Article，,卷期：2011年30-42] Akt activation is common in progressive thyroid cancer. In breast cancer, Akt1 induces primary cancer growth, but is reported to inhibit metastasis in vivo in several model systems. In contrast, clinical and in vitro stu... Activation of Notch1 signaling in stromal fibroblasts inhibits melanoma growth by upregulating WISP-1 [作者：Shao, H; Cai, L; Grichnik, JM; Livingstone, AS; Velazquez, OC; Liu, ZJ,期刊：Oncogene, 页码：4316-4326 , 文章类型： Article，,卷期：2011年30-42] The tumor microenvironment is emerging as an important target for cancer therapy. Fibroblasts (Fbs) within the tumor stroma are critically involved in promoting tumor growth and angiogenesis through secretion of soluble ... Differential regulation of PTEN expression by androgen receptor in prostate and breast cancers [作者：Wang, Y; Romigh, T; He, X; Tan, MH; Orloff, MS; Silverman, RH; Heston, WD; Eng, C,期刊：Oncogene, 页码：4327-4338 , 文章类型： Article，,卷期：2011年30-42] Prostate cancer and breast cancer are the most common malignancies in the western world. Androgen receptor (AR) and PTEN both have been well documented to have important roles in prostate carcinogenesis. In contrast, AR ... The tumor suppressor gene rap1GAP is silenced by miR-101-mediated EZH2 overexpression in invasive squamous cell carcinoma [作者：Banerjee, R; Mani, RS; Russo, N; Scanlon, CS; Tsodikov, A; Jing, X; Cao, Q; Palanisamy, N; Metwally, T; Inglehart, RC; Tomlins, S; Bradford, C; Carey, T; Wolf, G; Kalyana-Sundaram, S; Chinnaiyan, AM; Varambally, S; D'Silva, NJ,期刊：Oncogene, 页码：4339-4349 , 文章类型： Article，,卷期：2011年30-42] Rap1GAP is a critical tumor suppressor gene that is downregulated in multiple aggressive cancers, such as head and neck squamous cell carcinoma, melanoma and pancreatic cancer. However, the mechanistic basis of rap1GAP d... Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1 [作者：Li, C; Ao, J; Fu, J; Lee, DF; Xu, J; Lonard, D; O'Malley, BW,期刊：Oncogene, 页码：4350-4364 , 文章类型： Article，,卷期：2011年30-42] Steroid receptor co-activator-3 (SRC-3/AIB1) is an oncogene that is amplified and overexpressed in many human cancers. However, the molecular mechanisms that regulate 'activated SRC-3 oncoprotein' turnover during tumorig... Poly(ADP-ribose)-dependent regulation of Snail1 protein stability [作者：Rodriguez, MI; Gonzalez-Flores, A; Dantzer, F; Collard, J; de Herreros, AG; Oliver, FJ,期刊：Oncogene, 页码：4365-4372 , 文章类型： Article，,卷期：2011年30-42] Snail1 is a master regulator of the epithelial-mesenchymal transition (EMT) and has been implicated in key tumor biological processes such as invasion and metastasis. It has been previously shown that poly(ADP-ribose) po... Pleiotropic regulation of macrophage polarization and tumorigenesis by formyl peptide receptor-2 (vol 30, pg 3887, 2011) [作者：Li, Y; Cai, L; Wang, H; Wu, P; Gu, W; Chen, Y; Hao, H; Tang, K; Yi, P; Liu, M; Miao, S; Ye, D,期刊：Oncogene, 页码：4373-4374 , 文章类型： Correction，,卷期：2011年30-42] Requirement for chromatin-remodeling complex in novel tumor suppressor HIC1-mediated transcriptional repression and growth control (Retraction of vol 28, pg 651, 2009) [作者：Zhang, B; Chambers, KJ; Leprince, D; Faller, DV; Wang, S,期刊：Oncogene, 页码：4374-4374 , 文章类型： Correction，,卷期：2011年30-42]