- The thyroid lobes: The different twins
[作者：Albi, E; Curcio, F; Spelat, R; Lazzarini, R; Loreti, E; Ferri, I; Ambesi-Impiombato, FS,期刊：Archives of Biochemistry and Biophysics , 页码：16-22 , 文章类型： Article，,卷期：2012年518-1]
- Although differences in size of the right and left thyroid lobes are well defined, differences in morphology, follicles structure, cAMP production, thyrotropin receptor, and protein involved in cell signalling have not p...
- Sphingosine kinase 1 knockdown reduces insulin synthesis and secretion in a rat insulinoma cell line
[作者：Hasan, NM; Longacre, MJ; Stoker, SW; Kendrick, MA; Druckenbrod, NR; Laychock, SG; Mastrandrea, LD; MacDonald, MJ,期刊：Archives of Biochemistry and Biophysics , 页码：23-30 , 文章类型： Article，,卷期：2012年518-1]
- To evaluate the role of sphingosine kinase 1 (SphK1) in insulin secretion, we used stable transfection to knock down the expression of the Sphk1 gene in the rat insulinoma INS-1 832/13 cell line. Cell lines with lowered ...
- Autophagy enhanced phagocytosis of apoptotic cells by oridonin-treated human histocytic lymphoma U937 cells
[作者：Zang, LH; Xu, Q; Ye, YC; Li, X; Liu, YQ; Tashiro, S; Onodera, S; Ikejima, T,期刊：Archives of Biochemistry and Biophysics , 页码：31-41 , 文章类型： Article，,卷期：2012年518-1]
- Macrophages rapidly engulf and remove apoptotic cells to limit the release of noxious cellular contents and to restrict autoimmune disease or inflammation. Recent developments reveal an important role in autophagy for cl...
- Inhibition of hyaluronan synthesis reduced inflammatory response in mouse synovial fibroblasts subjected to collagen-induced arthritis
[作者：Campo, GM; Avenoso, A; D'Ascola, A; Prestipino, V; Scuruchi, M; Nastasi, G; Calatroni, A; Campo, S,期刊：Archives of Biochemistry and Biophysics , 页码：42-52 , 文章类型： Article，,卷期：2012年518-1]
- Hyaluronan (HA) fragments are able to induce inflammation by stimulating both CD44 and toll-like receptor 4 (TLR-4). CD44 and TLR-4 activation stimulates the liberation of NF-kappa B and pro-inflammatory cytokine respons...
- 1 alpha,25-Dihydroxyvitamin D-3 and its analog, 2-methylene-19-nor-(20S)-1 alpha, 25-dihydroxyvitamin D-3 (2MD), suppress intraocular pressure in non-human primates
[作者：Kutuzova, GD; Gabelt, BT; Kiland, JA; Hennes-Beann, EA; Kaufman, PL; DeLuca, HF,期刊：Archives of Biochemistry and Biophysics , 页码：53-60 , 文章类型： Article，,卷期：2012年518-1]
- Ocular hypertension is the greatest known risk factor for glaucoma that affects an estimated 70 million people worldwide. Lowering intraocular pressure (IOP) remains the mainstay of therapy in the management of glaucoma....
- Naringin ameliorates metabolic syndrome by activating AMP-activated protein kinase in mice fed a high-fat diet
[作者：Pu, P; Gao, DM; Mohamed, S; Chen, J; Zhang, J; Zhou, XY; Zhou, NJ; Xie, J; Jiang, H,期刊：Archives of Biochemistry and Biophysics , 页码：61-70 , 文章类型： Article，,卷期：2012年518-1]
- Metabolic syndrome is a low-grade inflammatory state in which oxidative stress is involved. Naringin, isolated from the Citrussinensis, is a phenolic compound with anti-oxidative and anti-inflammatory activities. The aim...
- PPAR alpha activation inhibits endothelin-1-induced cardiomyocyte hypertrophy by prevention of NFATc4 binding to GATA-4
[作者：Le, K; Li, RF; Xu, SW; Wu, XQ; Huang, HQ; Bao, YX; Cai, Y; Lan, T; Moss, J; Li, CX; Zou, J; Shen, XY; Liu, PQ,期刊：Archives of Biochemistry and Biophysics , 页码：71-78 , 文章类型： Article，,卷期：2012年518-1]
- Peroxisome proliferator-activated receptor alpha (PPAR alpha) has been implicated in the pathogenesis of cardiac hypertrophy, although its mechanism of action remains largely unknown. To determine the effect of PPARa act...
- p53 mutants induce transcription of NF-kappa B2 in H1299 cells through CBP and STAT binding on the NF-kappa B2 promoter and gain of function activity
[作者：Vaughan, CA; Singh, S; Windle, B; Sankala, HM; Graves, PR; Yeudall, WA; Deb, SP; Deb, S,期刊：Archives of Biochemistry and Biophysics , 页码：79-88 , 文章类型： Article，,卷期：2012年518-1]
- Cancer cells with p53 mutations, in general, grow more aggressively than those with wild-type p53 and show "gain of function" (GOF) phenotypes such as increased growth rate, enhanced resistance to chemotherapeutic drugs,...
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