- Toward MSC in Solid Organ Transplantation: 2008 Position Paper of the MISOT Study Group
[作者:Dahlke, MH; Hoogduijn, M; Eggenhofer, E; Popp, FC; Renner, P; Slowik, P; Rosenauer, A; Piso, P; Geissler, EK; Lange, C; Chabannes, D; Mazzanti, B; Bigenzahn, S; Bertolino, P; Kunter, U; Introna, M; Rambaldi, A; Capelli, C; Perico, N; Casiraghi, F; Noris, M; Gotti, E; Seifert, M; Saccardi, R; Verspaget, HW; van Hoek, B; Bartholomew, A; Wekerle, T; Volk, HD; Remuzzi, G; Deans, R; Lazarus, H; Schlitt, HJ; Baan, CC,期刊:Transplantation, 页码:614-619 , 文章类型: Article,,卷期:2009年88-5]
- The following position paper summarizes the recommendations for early clinical trials and ongoing basic research in the field of mesenchymal stem cell-induced solid organ graft acceptance-agreed upon on the first meeting...
- Impaired Effector Memory T-Cell Regulation Facilitates Graft Versus Host Disease in CCR7-Deficient Bone Marrow Transplant Chimeras
[作者:de Jager, SCA; Cante-Barrett, K; Bot, I; Husberg, C; van Puijvelde, GH; van Santbrink, PJ; Yndestad, A; van den Oever, JME; Kuiper, J; van Berkel, TJC; Lipp, M; Zwaginga, JJ; Fibbe, WE; Aukrust, P; Biessen, EAL,期刊:Transplantation, 页码:631-639 , 文章类型: Article,,卷期:2009年88-5]
- Background. The development of graft versus host disease (GvHD) is one of the major challenges of bone marrow transplantations (BMTs). Although clinical symptoms of GvHD share many features with auto immune diseases, the...
- TNF-alpha Signaling is Not Required for In Vivo Transcriptional Reactivation of Latent Murine Cytomegalovirus
[作者:Zhang, Z; Li, ZG; Yan, SX; Wang, XQ; Abecassis, M,期刊:Transplantation, 页码:640-645 , 文章类型: Article,,卷期:2009年88-5]
- Background. Reactivation of cytornegalovirus (CMV) is frequently observed in recipients of solid organs and bone marrow transplants and is associated with increased risk of acute and chronic allograft rejection, opportun...
- Mammalian Target of Rapamycin Inhibition Prevents Glomerular Hypertrophy in a Model of Renal Mass Reduction
[作者:Rovira, J; Arellano, EM; Carreras, J; Campos, B; Vodenik, B; Banon-Maneus, E; Ramirez-Bajo, MJ; Moya-Rull, D; Sole-Gonzalez, A; Hernandez, A; Revuelta, I; Quintana, LF; Howat, WJ; Campistol, JM; Diekmann, F,期刊:Transplantation, 页码:646-652 , 文章类型: Article,,卷期:2009年88-5]
- Background. Sirolimus (SRL) is a potent and specific immunosuppressive drug used in organ transplantation, as basic therapy or in combination with calcineurin inhibitors. Although SRL is a nonnephrotoxic drug, many repor...
- Donor HO-1 Expression Inhibits Intimal Hyperplasia in Unmanipulated Graft Recipients: A Potential Role for CD8(+) T-Cell Modulation by Carbon Monoxide
[作者:Clarke, HM; Shrivastava, S; Motterlini, R; Sawle, P; Chen, DX; Dorling, A,期刊:Transplantation, 页码:653-661 , 文章类型: Article,,卷期:2009年88-5]
- Background. Induction of heme oxygenase (HO)-1 expression protects transplanted organs from humoral rejection and ischemia-reperfusion injury, but induction in recipient immune cells also has direct immunomodulatory effe...
- Short-Term Outcomes for Obese Live Kidney Donors and Their Recipients
[作者:Reese, PP; Feldman, HI; Asch, DA; Thomasson, A; Shults, J; Bloom, RD,期刊:Transplantation, 页码:662-671 , 文章类型: Article,,卷期:2009年88-5]
- Background. Given the association between obesity and kidney disease, transplant professionals have debated the appropriateness of accepting obese live kidney donors. We hypothesized that compared with normal weight dono...
- Experience From an Active Preemptive Kidney Transplantation Program-809 Cases Revisited
[作者:Witczak, BJ; Leivestad, T; Line, PD; Holdaas, H; Reisaeter, AV; Jenssen, TG; Midtvedt, K; Bitter, J; Hartmann, A,期刊:Transplantation, 页码:672-677 , 文章类型: Article,,卷期:2009年88-5]
- Background. Preemptive kidney transplantation (PKT) is increasingly acknowledged. We wanted to investigate the results of an active PKT policy in an unselected end-stage renal disease population with high prevalence of P...
- Hyperparathyroidism and Vitamin D Deficiency Predispose to Bone Loss in Renal Transplant Recipients
[作者:Lim, WH; Coates, PS; Russ, GR; Coates, PTH,期刊:Transplantation, 页码:678-683 , 文章类型: Article,,卷期:2009年88-5]
- Background. Bone disease is common postrenal transplantation resulting in increased fracture rates and morbidity. The cause is multifactorial including hyperparathyroidism, corticosteroids, and possibly calcium and vitam...
- Outcomes With Conversion From Calcineurin Inhibitors to Sirolimus After Renal Transplantation in the Context of Steroid Withdrawal or Steroid Continuation
[作者:Egbuna, OI; Davis, RB; Chudinski, R; Pavlakis, M; Rogers, C; Molakatalla, P; Johnson, SR; Karp, S; Monaco, AP; Tang, HY; Hanto, DW; Mandelbrot, DA,期刊:Transplantation, 页码:684-692 , 文章类型: Article,,卷期:2009年88-5]
- Background. A number of studies have suggested that conversion from calcineurin inhibitors (CNI) to sirolimus (SRL) can improve graft function in renal transplant patients. None of these studies has converted patients to...
- Association of Common Type 2 Diabetes Risk Gene Variants and Posttransplantation Diabetes Mellitus in Renal Allograft Recipients in Korea
[作者:Kang, ES; Kim, MS; Kim, CH; Nam, CM; Han, SJ; Hur, KY; Ahn, CW; Cha, BS; Kim, SI; Lee, HC; Kim, YS,期刊:Transplantation, 页码:693-698 , 文章类型: Article,,卷期:2009年88-5]
- Background. Posttransplantation diabetes mellitus (PTDM) is a major metabolic complication in renal transplant recipients. Recent genome-wide association studies have identified several genes associated with type 2 diabe...
- Impact of Polymorphisms of TLR4/CD14 and TLR3 on Acute Rejection in Kidney Transplantation
[作者:Hwang, YH; Ro, H; Choi, I; Kim, H; Oh, KH; Hwang, JI; Park, MH; Kim, S; Yang, J; Ahn, C,期刊:Transplantation, 页码:699-705 , 文章类型: Article,,卷期:2009年88-5]
- Background. Organ transplantation itself inevitably activates the innate immune system by toll-like receptors (TLRs), potentially leading to allograft rejection and graft failure. We evaluated the possible association be...
- Recurrent Nonhepatic and De Novo Malignancies After Liver Transplantation
[作者:Jain, A; Fiaz, O; Sheikh, B; Sharma, R; Safadjou, S; Kashyap, R; Bryan, L; Batzold, P; Orloff, M,期刊:Transplantation, 页码:706-710 , 文章类型: Article,,卷期:2009年88-5]
- Introduction. After Liver transplantation (LTx), recurrence of hepatic cancer, de novo cancers, and donor-transmitted cancers have been described. However, the data for patients with a prior history of nonhepatic maligna...
- Improved Outcomes of Combined Liver and Kidney Transplants in Small Children (< 15 kg)
[作者:Perera, MTPR; Silva, MA; Sharif, K; McKiernan, PJ; Kelly, DA; Lloyd, C; Milford, DV; Mayer, DA; Mirza, DF,期刊:Transplantation, 页码:711-715 , 文章类型: Article,,卷期:2009年88-5]
- Background. Combined liver and kidney transplantation (CLKT) is a surgical challenge in small children because of technical aspects, lack of pediatric donors, and restrictions related to the size of the abdominal cavity....
- A Rapid and Reliable Means of Assessing Hepatic Steatosis In Vivo Via Electrical Bioimpedance
[作者:Hessheimer, AJ; Parramon, D; Guimera, A; Erill, I; Rimola, A; Garcia-Valdecasas, JC; Villa, R; Fondevila, C,期刊:Transplantation, 页码:716-722 , 文章类型: Article,,卷期:2009年88-5]
- Background. In liver transplantation, macrovesicular steatosis is a major determinant of graft outcome. Visual assessment of steatosis by the donor surgeon is highly inaccurate, whereas hepatic biopsy is user dependent a...
- No Difference in Transplant Outcomes for Local and Import Pancreas Allografts
[作者:Fridell, JA; Mangus, RS; Hollinger, EF; Milgrom, ML; Taber, TE; Mohler, E; Good, J; Goble, ML; Powelson, JA,期刊:Transplantation, 页码:723-728 , 文章类型: Article,,卷期:2009年88-5]
- Background. In the United States, pancreas allograft allocation is strictly regulated. Local centers have the first option to accept an organ, followed by regional and national allocation for those not accepted locally. ...
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