- Photoactivation switch from type II to type I reactions by electron-rich micelles for improved photodynamic therapy of cancer cells under hypoxia
[作者:Ding, HY; Yu, HJ; Dong, Y; Tian, RH; Huang, G; Boothman, DA; Sumer, BD; Gao, JM,期刊:Journal of controlled release, 页码:276-280 , 文章类型: Article,,卷期:2011年156-3]
- Photodynamic therapy (PDT) is an emerging clinical modality for the treatment of a variety of diseases. Most photo-sensitizers are hydrophobic and poorly soluble in water. Many new nanoplatforms have been successfully es...
- An in vitro assay based on surface plasmon resonance to predict the in vivo circulation kinetics of liposomes
[作者:Crielaard, BJ; Yousefi, A; Schillemans, JP; Vermehren, C; Buyens, K; Braeckmans, K; Lammers, T; Storm, G,期刊:Journal of controlled release, 页码:307-314 , 文章类型: Article,,卷期:2011年156-3]
- The adsorption of blood proteins onto liposomes and other colloidal particles is an important process influencing the circulation time. Proteins adsorbed to the surface of liposomes can mediate recognition of the liposom...
- Cancer treatment using an optically inert Rose Bengal derivative combined with pulsed focused ultrasound
[作者:Kim, YS; Rubio, V; Qi, JJ; Xia, RM; Shi, ZZ; Peterson, L; Tung, CH; O'Neill, BE,期刊:Journal of controlled release, 页码:315-322 , 文章类型: Article,,卷期:2011年156-3]
- Pulsed high intensity focused ultrasound (HIFU) has been combined with a photo-insensitive Rose Bengal derivative (RB2) to provide a synergistic cytotoxicity requiring the presence of both ultrasonic cavitation and drug....
- PEG-stabilized lipid disks as carriers for amphiphilic antimicrobial peptides
[作者:Zetterberg, MM; Reijmar, K; Pranting, M; Engstrom, A; Andersson, DI; Edwards, K,期刊:Journal of controlled release, 页码:323-328 , 文章类型: Article,,卷期:2011年156-3]
- Antimicrobial peptides hold potential as a possible alternative, or complement, to conventional antibiotics but new, safe and efficient means are needed for formulation and administration of the peptides. In this study w...
- Protein macromonomers containing reduction-sensitive linkers for covalent immobilization and glutathione triggered release from dextran hydrogels
[作者:Verheyen, E; van der Wal, S; Deschout, H; Braeckmans, K; de Smedt, S; Barendregt, A; Hennink, WE; van Nostrum, CF,期刊:Journal of controlled release, 页码:329-336 , 文章类型: Article,,卷期:2011年156-3]
- We report an efficient strategy to conjugate methacrylamide moieties to the lysine units of lysozyme for copolymerization and subsequent triggered release from hydrogels. Two novel linker molecules, containing an ester b...
- Involvement of activated transcriptional process in efficient gene transfection using unmodified and mannose-modified bubble lipoplexes with ultrasound exposure
[作者:Un, K; Kawakami, S; Higuchi, Y; Suzuki, R; Maruyama, K; Yamashita, F; Hashida, M,期刊:Journal of controlled release, 页码:355-363 , 文章类型: Article,,卷期:2011年156-3]
- Recently, our group developed ultrasound (US)-responsive and mannose-modified gene carriers (Man-PEG(2000) bubble lipoplexes), and successfully obtained a high level of gene expression in mannose receptor-expressing cell...
- Effect of integrin targeting and PEG shielding on polyplex micelle internalization studied by live-cell imaging
[作者:Mickler, FM; Vachutinsky, Y; Oba, M; Miyata, K; Nishiyama, N; Kataoka, K; Brauchle, C; Ruthardt, N,期刊:Journal of controlled release, 页码:364-373 , 文章类型: Article,,卷期:2011年156-3]
- alpha(v)beta(3) and alpha(v)beta(5) integrins are attractive target structures for cancer therapy as they are upregulated in tumor and tumor associated host cells and play a pivotal role for tumor growth and metastasis. ...
- Tumour necrosis factor-alpha increases extravasation of virus particles into tumour tissue by activating the Rho A/Rho kinase pathway
[作者:Seki, T; Carroll, F; Illingworth, S; Green, N; Cawood, R; Bachtarzi, H; Subr, V; Fisher, KD; Seymour, LW,期刊:Journal of controlled release, 页码:381-389 , 文章类型: Article,,卷期:2011年156-3]
- Tumour Necrosis Factor alpha (TNF) is a pleiotropic pro-inflammatory cytokine with known vascular permeabilising activity. It is employed during isolated limb perfusion to enhance delivery of chemotherapeutic drugs into ...
- Immobilization of protein-coated drug nanoparticles in nanofibrillar cellulose matrices-Enhanced stability and release
[作者:Valo, H; Kovalainen, M; Laaksonen, P; Hakkinen, M; Auriola, S; Peltonen, L; Linder, M; Jarvinen, K; Hirvonen, J; Laaksonen, T,期刊:Journal of controlled release, 页码:390-397 , 文章类型: Article,,卷期:2011年156-3]
- Nanosizing is an advanced approach to overcomepoor aqueous solubility of active pharmaceutical ingredients. One main problem in pharmaceutical nanotechnology is maintaining of the morphology of the nanometer sized partic...
- Highly selective in-vivo imaging of tumor as an inflammation site by ROS detection using hydrocyanine-conjugated, functional nano-carriers
[作者:Kim, JY; Il Choi, W; Kim, YH; Tae, G,期刊:Journal of controlled release, 页码:398-405 , 文章类型: Article,,卷期:2011年156-3]
- Previously, the optical imaging of chitosan-functionalized, Pluronic-based nano-carriers by Cy5.5 conjugation revealed a good tumor targeting characteristic of the nano-carriers in vivo [J. Control. Release, 147 (2010) 1...
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