- Structural Insights on the New Mechanism of Trehalose Synthesis by Trehalose Synthase TreT from Pyrococcus horikoshii
[作者：Woo, EJ; Ryu, SI; Song, HN; Jung, TY; Yeon, SM; Lee, HA; Park, BC; Park, KH; Lee, SB,期刊：Journal of Molecular Biology, 页码：247-259 , 文章类型： Article，,卷期：2010年404-2]
- Many microorganisms produce trehalose for stability and survival against various environmental stresses. Unlike the widely distributed trehalose biosynthetic pathway, which utilizes uridine diphosphate glucose and glucos...
- Induced-fit upon Ligand Binding Revealed by Crystal Structures of the Hot-dog Fold Thioesterase in Dynemicin Biosynthesis
[作者：Liew, CW; Sharff, A; Kotaka, M; Kong, R; Sun, HH; Qureshi, I; Bricogne, G; Liang, ZX; Lescar, J,期刊：Journal of Molecular Biology, 页码：291-306 , 文章类型： Article，,卷期：2010年404-2]
- Dynemicins are structurally related 10-membered enediyne natural products isolated from Micromonospora chernisa with potent antitumor and antibiotic activity. The early biosynthetic steps of the enediyne moiety of dynemi...
- A pH-Dependent Dimer Lock in Spider Silk Protein
[作者：Landreh, M; Askarieh, G; Nordling, K; Hedhammar, M; Rising, A; Casals, C; Astorga-Wells, J; Alvelius, G; Knight, SD; Johansson, J; Jornvall, H; Bergman, T,期刊：Journal of Molecular Biology, 页码：328-336 , 文章类型： Article，,卷期：2010年404-2]
- Spider dragline silk, one of the strongest polymers in nature, is composed of proteins termed major ampullate spidroin (MaSp) 1 and MaSp2. The N-terminal (NT) domain of MaSp1 produced by the nursery web spider Euprosthen...
- The Role of Protein Sequence and Amino Acid Composition in Amyloid Formation: Scrambling and Backward Reading of IAPP Amyloid Fibrils
[作者：Sabate, R; Espargaro, A; de Groot, NS; Valle-Delgado, JJ; Fernandez-Busquets, X; Ventura, S,期刊：Journal of Molecular Biology, 页码：337-352 , 文章类型： Article，,卷期：2010年404-2]
- The specific functional structure of natural proteins is determined by the way in which amino acids are sequentially connected in the polypeptide. The tight sequence/structure relationship governing protein folding does ...
- The Roles of Stress-Activated Sty1 and Gcn2 Kinases and of the Protooncoprotein Homologue Int6/eIF3e in Responses to Endogenous Oxidative Stress during Histidine Starvation
[作者：Nemoto, N; Udagawa, T; Ohira, T; Jiang, L; Hirota, K; Wilkinson, CRM; Bahler, J; Jones, N; Ohta, K; Wek, RC; Asano, K,期刊：Journal of Molecular Biology, 页码：183-201 , 文章类型： Article，,卷期：2010年404-2]
- In fission yeast, Sty1 and Gcn2 are important protein kinases that regulate gene expression in response to amino acid starvation. The translation factor subunit Int6/eIF3e promotes Sty1-dependent response by increasing t...
- Two Stacked Heme Molecules in the Binding Pocket of the Periplasmic Heme-Binding Protein HmuT from Yersinia pestis
[作者：Mattle, D; Zeltina, A; Woo, JS; Goetz, BA; Locher, KP,期刊：Journal of Molecular Biology, 页码：220-231 , 文章类型： Article，,卷期：2010年404-2]
- The periplasmic binding protein HmuT from Yersinia pestis (YpHmuT) is a component of the heme uptake locus hmu and delivers bound hemin to the inner-membrane-localized, ATP-binding cassette (ABC) transporter HmuUV for tr...
- Solution Structure of the Catalytic Domain of the Mitochondrial Protein ICT1 That Is Essential for Cell Vitality
[作者：Handa, Y; Hikawa, Y; Tochio, N; Kogure, H; Inoue, M; Koshiba, S; Guntert, P; Inoue, Y; Kigawa, T; Yokoyama, S; Nameki, N,期刊：Journal of Molecular Biology, 页码：260-273 , 文章类型： Article，,卷期：2010年404-2]
- The ICT1 protein was recently reported to be a component of the human mitoribosome and to have codon-independent peptidyl-tRNA hydrolysis activity via its conserved GGQ motif, although little is known about the detailed ...
- Dynamic Interactions between Clathrin and Locally Structured Elements in a Disordered Protein Mediate Clathrin Lattice Assembly
[作者：Zhuo, Y; Ilangovan, U; Schirf, V; Demeler, B; Sousa, R; Hinck, AP; Lafer, EM,期刊：Journal of Molecular Biology, 页码：274-290 , 文章类型： Article，,卷期：2010年404-2]
- Assembly of clathrin lattices is mediated by assembly/adaptor proteins that contain domains that bind lipids or membrane-bound cargo proteins and clathrin binding domains (CBDs) that recruit clathrin. Here, we characteri...
- Design, Production and Molecular Structure of a New Family of Artificial Alpha-helicoidal Repeat Proteins (alpha Rep) Based on Thermostable HEAT-like Repeats
[作者：Urvoas, A; Guellouz, A; Valerio-Lepiniec, M; Graille, M; Durand, D; Desravines, DC; van Tilbeurgh, H; Desmadril, M; Minard, P,期刊：Journal of Molecular Biology, 页码：307-327 , 文章类型： Article，,卷期：2010年404-2]
- Repeat proteins have a modular organization and a regular architecture that make them attractive models for design and directed evolution experiments. HEAT repeat proteins, although very common, have not been used as a s...
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