- Frequent splicing aberration of the base excision repair gene hMYH in human gastric cancer
[作者:Kobayashi, K; Shida, A; Yamada, H; Ishibashi, Y; Nakayama, R; Toriumi, Y; Mitsumori, N; Kashiwagi, H; Yanaga, K,期刊:Anticancer Research, 页码:215-221 , 文章类型: Article,,卷期:2008年28-1A]
- Background: Missense mutation of hMYH, which prevents transversion mutations induced by oxidative DNA damage, is reportedly associated with the development of gastric and colon cancer. We investigated whether deficiency ...
- Inhibition of both mesothelioma cell growth and Cdk4 activity following treatment with a TATp16(INK4a) peptide
[作者:Frizelle, SP; Kratzke, MG; Carreon, RR; Engel, SC; Youngquist, L; Klein, MA; Fourre, L; Shekels, LL; Kratzke, RA,期刊:Anticancer Research, 页码:1-7 , 文章类型: Article,,卷期:2008年28-1A]
- Disruption of the 9p21 locus is common in mesothelioma and leads to loss of both the p16(INK4a) and the p14(ARF) gene products. This study tested the hypothesis that re-expression of p16(INK4a) carried out using the TAT ...
- Cell cycle perturbation and acquired 5-fluorouracil chemoresistance
[作者:Guo, XX; Goessl, E; Collie-Duguid, ESR; Cassidy, J; Wang, WG; O'Brien, V,期刊:Anticancer Research, 页码:9-14 , 文章类型: Article,,卷期:2008年28-1A]
- Acquired chemoresistance is one of the obstacles for success of 5-fluorouracil (5-FU)-based cancer chemotherapy. Some molecular mechanisms of acquired 5-FU resistance are still unknown. We have recently demonstrated down...
- The utility of vitamin K3 (menadione) against pancreatic cancer
[作者:Osada, S; Tomita, H; Tanaka, Y; Tokuyama, Y; Tanaka, H; Sakashita, F; Takahashi, T,期刊:Anticancer Research, 页码:45-50 , 文章类型: Article,,卷期:2008年28-1A]
- Background: To evaluate the efficacy of vitamin K3 (VK3) against pancreatic cancer, the molecular mechanism of VK3 or gemcitabine (GEM)-induced inhibition of proliferation was characterized. Materials and Methods: The ce...
- Adenovirus vector-mediated gene therapy using iodized oil esters for hepatocellular carcinoma in rats
[作者:Shiba, H; Misawa, T; Iida, T; Okamoto, T; Futagawa, Y; Sakurai, M; Ohashi, T; Eto, Y; Yanaga, K,期刊:Anticancer Research, 页码:51-53 , 文章类型: Article,,卷期:2008年28-1A]
- Background: When gene therapy is performed for malignant tumors, gene transfer efficiency and selectivity are extremely important. The usefulness of gene therapy by intra-arterial injection of an adenovirus vector with i...
- Effect of pO(2) on antitumor drug cytotoxicity on MDR and non-MDR variants selected from the LoVo metastatic colon carcinoma cell line
[作者:Lelong-Rebel, I; Brisson, C; Fabre, M; Bergerat, JP; Rebel, G,期刊:Anticancer Research, 页码:55-68 , 文章类型: Article,,卷期:2008年28-1A]
- Two chemosensitive cell lines, LoVo-fusoid (LoVof) and LoVo-small cells (LoVo-sc) were derived from the original LoVo cell line. These two variants and the multidrug-resistant (MDR) cell line LoVo-Dox were screened for v...
- Feasibility of induction heating using a sintered MgFe2O4 needle for minimally invasive breast cancer therapy
[作者:Yukumi, S; Watanabe, Y; Horiuchi, A; Doi, T; Sato, K; Yoshida, M; Maehara, T; Aono, H; Naohara, T; Kawachi, K,期刊:Anticancer Research, 页码:69-74 , 文章类型: Article,,卷期:2008年28-1A]
- Background: This study investigated a novel approach for tumor ablation therapy using an alternating magnetic field combined with a sintered MgFe2O4 needle. This method differs from radiofrequency ablation (RFA) by diele...
- Parasporin-1Ab, a novel Bacillus thuringiensis cytotoxin preferentially active on human cancer cells in vitro
[作者:Uemori, A; Ohgushi, A; Yasutake, K; Maeda, M; Mizuki, E; Ohba, M,期刊:Anticancer Research, 页码:91-95 , 文章类型: Article,,卷期:2008年28-1A]
- The non-insecticidal Bacillus thuringiensis strain B0195 produces parasporin (PS) whose cytocidal activity is preferential for human cancer cells. This study identified two ps genes, ps1Aa3 and ps1Ab1, from the strain B0...
- Polymorphisms of death pathway genes FAS and FASL and risk of premalignant gastric lesions
[作者:Hsu, PI; Lu, PJ; Wang, EM; Ger, LP; Lo, GH; Tsay, FW; Chen, TA; Yang, HB; Chen, HC; Lin, WS; Lai, KH,期刊:Anticancer Research, 页码:97-103 , 文章类型: Article,,卷期:2008年28-1A]
- Background: Tumorigenesis is a multistep process that begins with the abrogation of normal controls of apoptosis and cell proliferation, and the FAS receptor-ligand system is a key regulator of apoptosis. The aim of this...
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