In an antibiotic lead discovery program, the known strain Streptomyces armeniacus DSM19369 has been found to produce three new natural products when cultivated on a malt-containing medium. The challenging structural eluc...
Facile synthesis of meso-aryl-substituted 5,15-dithiaporphyrins and 10-thiacorroles has been achieved by sulfidation of a,a'-dichlorodipyrrin metal complexes with sodium sulfide in DMF. Thiacorrole metal complexes exhibi...
A new unsymmetrical geminal dianion that contained both a phosphine oxide moiety and a phosphine sulfide moiety has been synthesized. Its reactivity towards RuII was explored, which led to the formation of a highly react...
Disubstituted thienyl-, furyl- and pyridylmagnesium derivatives are regioselectively prepared from a Br/Mg exchange of the corresponding dibromo compounds by using either iPrMgCl center dot LiCl or hindered arylmagnesium...
Carbene?chalcogenophosphenium adducts, which correspond to an intermolecular stabilization mode of the so far elusive, free oxo- and thiooxophosphenium species [R2P+=X] (X=O, S) by imidazolylidene (NHC) and diaminocyclop...
Pluronic F-127 hydrogels are highly efficient microenvironments for photochemical reactions, as demonstrated for singlet oxygen reactions of monoalkenes. Nonpolar substrates are localized in the nanosized polymer compart...
Enzyme-labile protecting groups have emerged as a green alternative to conventional protecting groups. These groups introduce a further orthogonal dimension and eco-friendliness into protection schemes for the synthesis ...
A general and efficient method for the palladium-catalyzed carbonylative coupling of aryl iodides to benzyl acetylenes has been developed. Various furanones have been prepared in excellent yields from their corresponding...
The labile complex [MoCl(eta 3-methallyl)(CO)2(NCMe)2] reacts with the ligand 1,4,7-trithiacyclononane ([9]aneS3) and the salt NaBAr'4 to afford [Mo(eta 3-methallyl)(CO)2([9]aneS3)][BAr'4] (1 center dot BAr'4). An analog...
New hemicyanine dyes (CM101, CM102, CM103, and CM104) in which tetrahydroquinoline derivatives are used as electron donors and N-(carboxymethyl)-pyridinium is used as an electron acceptor and anchoring group were designe...
The development of a pseudorotaxane motif capable of performing unidirectional threading and dethreading processes under control of external stimuli is particularly important for the construction of processive linear mot...
Metal ions Cu, Zn and Fe, seem to play a pivotal role in Alzheimers disease and other neurodegenerative diseases. In order to understand this in a broader sense, one has to considerer the peculiarities of metal metabolis...