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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共19条记录   Monitoring Inhibitor-Induced Conformational Population Shifts in HIV-1 Protease by Pulsed EPR Spectroscopy [作者：Blackburn, ME; Veloro, AM; Fanucci, GE,期刊：Biochemistry, 页码：8765-8767 , 文章类型： Article，,卷期：2009年48-37] Double electron-electron resonance (DEER), a pulsed electron paramagnetic resonance (EPR) spectroscopy technique, was utilized to characterize conformational population shifts in HIV-1 protease (HIV-1PR) upon interaction... Structure of Psb27 in Solution: Implications for Transient Binding to Photosystem II during Biogenesis and Repair [作者：Cormann, KU; Bangert, JA; Ikeuchi, M; Rogner, M; Stoll, R; Nowaczyk, MM,期刊：Biochemistry, 页码：8768-8770 , 文章类型： Article，,卷期：2009年48-37] Psb27 is a membrane-extrinsic Subunit of photosystem II (PSII) where It is involved in the assembly and maintenance of this large membrane protein complex that catalyzes one of the key reactions in the biosphere, the lig... Solution Structure of Psb27 from Cyanobacterial Photosystem II [作者：Mabbitt, PD; Rautureau, GJP; Day, CL; Wilbanks, SM; Eaton-Rye, JJ; Hinds, MG,期刊：Biochemistry, 页码：8771-8773 , 文章类型： Article，,卷期：2009年48-37] Psb27 is a highly conserved component of photosystem II. The three-dimensional structure has a well-defined helical core, composed of four helices arranged ill a right-handed up-down-Up-down fold, with a less ordered reg... The Glutamate Switch Is Present in All Seven Clades of AAA plus Protein [作者：Mogni, ME; Costa, A; Ioannou, C; Bell, SD,期刊：Biochemistry, 页码：8774-8775 , 文章类型： Article，,卷期：2009年48-37] Recent work has identified a "glutamate switch" in six of the seven clades of AAA+ ATPases. The glutamate switch acts to transduce information regarding substrate binding to the ATPase active site. We provide biochemical... Chemical Tools for Dissecting Bacterial Physiology and Virulence [作者：Stanley, SA; Hung, DT,期刊：Biochemistry, 页码：8776-8786 , 文章类型： Article，,卷期：2009年48-37] Increasingly, chemical biology is being used in the context of bacterial virulence and the host-pathogen interaction, as small molecule inhibitors provide a number of unique advantages or the study of bacterial pathogens... Portability of the GN(R)A Hairpin Loop Motif between RNA and DNA [作者：Blose, JM; Lloyd, KP; Bevilacqua, PC,期刊：Biochemistry, 页码：8787-8794 , 文章类型： Article，,卷期：2009年48-37] Hairpins are common nucleic acid secondary structures that serve many structural and functional roles. Recently, We reported that r(UNCG) and r(GNRA) hairpin families use molecular mimicry and electrostatic factors to at... Structural Basis for Differential Binding of the Interleukin-8 Monomer and Dimer to the CXCR1 N-Domain: Role of Coupled Interactions and Dynamics [作者：Ravindran, A; Joseph, PRB; Rajarathnam, K,期刊：Biochemistry, 页码：8795-8805 , 文章类型： Article，,卷期：2009年48-37] Interleukin-8 (IL-8 or CXCL8) plays a critical role in orchestrating the immune response by binding and activating the receptor CXCR1 that belongs to the GPCR class. IL-8 exists as both monomers and drillers, and both bi... Arsenic Metalation of Seaweed Fucus vesiculosus Metallothionein: The Importance of the Interdomain Linker in Metallothionein [作者：Ngu, TT; Lee, JA; Rushton, MK; Stillman, MJ,期刊：Biochemistry, 页码：8806-8816 , 文章类型： Article，,卷期：2009年48-37] The presence or metallothionein in seaweed Fucus vesiculosus has been Suggested as the protecting agent against toxic metals in the contaminated waters it call grow in, We report the first kinetic pathway data for As3+ b... The ALS-Associated Mutation G93A in Human Copper-Zinc Superoxide Dismutase Selectively Destabilizes the Remote Metal Binding Region [作者：Museth, AK; Brorsson, AC; Lundqvist, M; Tibell, LAE; Jonsson, BH,期刊：Biochemistry, 页码：8817-8829 , 文章类型： Article，,卷期：2009年48-37] More than 100 distinct mutations in the gene (SOD 1) for human copper-zinc superoxide dismutase (CuZnSOD) have been associated with familial amyotrophic lateral sclerosis (fALS). Studies of these mutant proteins, which o... Complete Characterization of the Seventeen Step Moenomycin Biosynthetic Pathway [作者：Ostash, B; Doud, EH; Lin, C; Ostash, I; Perlstein, DL; Fuse, S; Wolpert, M; Kahne, D; Walker, S,期刊：Biochemistry, 页码：8830-8841 , 文章类型： Article，,卷期：2009年48-37] The moenomycins are phosphoglycolipid antibiotics produced by Streptomyces ghanaensis and related organisms. The phosphoglycolipids are the only known active site inhibitors of the peptidoglycan glycosyltransferases, all... Use of Stabilizing Mutations To Engineer a Charged Group within a Ligand-Binding Hydrophobic Cavity in T4 Lysozyme [作者：Liu, LJ; Baase, WA; Michael, MM; Matthews, BW,期刊：Biochemistry, 页码：8842-8851 , 文章类型： Article，,卷期：2009年48-37] Both large-to-small and nonpolar-to-polar mutations in the hydrophobic core of T4 lysozyme cause significant loss in stability. By including supplementary stabilizing mutations we constructed a variant that combines the ... Residues in the H+ Translocation Site Define the pK(a) for Sugar Binding to LacY [作者：Smirnova, I; Kasho, V; Sugihara, J; Choe, JY; Kaback, HR,期刊：Biochemistry, 页码：8852-8860 , 文章类型： Article，,卷期：2009年48-37] A remarkably high pK(a) of approximately 10.5 has been determined for sugar-binding affinity to the lactose permease of Escherichia coli (LacY), indicating that, under physiological conditions, substrate binds to fully p... Conformational Heterogeneity and Quasi-Static Self-Quenching in DNA Containing a Fluorescent Guanine Analogue, 3MI or 6MI [作者：Poulin, KW; Smirnov, AV; Hawkins, ME; Balis, FM; Knutson, JR,期刊：Biochemistry, 页码：8861-8868 , 文章类型： Article，,卷期：2009年48-37] Two different microenvironments in the DNA sequence 5'-act aGa gat ccc tca gac cct ttt agt cag tGt gga-3' (in both single-and double-stranded forms) are explored using two similar fluorescent nucleoside analogues, 3MI an... Disulfide Bond Formation in Yeast NAD(+)-Specific Isocitrate Dehydrogenase [作者：Garcia, JA; Minard, KI; Lin, AP; McAlister-Henn, L,期刊：Biochemistry, 页码：8869-8878 , 文章类型： Article，,卷期：2009年48-37] The tricarboxylic acid cycle NAD(+)-specific isocitrate dehydrogenase (IDH) of Saccharomyces cerevisiae is an octameric enzyme composed of four heterodimers of regulatory IDH I and catalytic IDH2 Subunits. Recent structu... The Mechanism of the Reaction Catalyzed by Uronate Isomerase Illustrates How an Isomerase May Have Evolved from a Hydrolase within the Amidohydrolase Superfamily [作者：Nguyen, TT; Fedorov, AA; Williams, L; Fedorov, EV; Li, YC; Xu, CF; Almo, SC; Raushel, FM,期刊：Biochemistry, 页码：8879-8890 , 文章类型： Article，,卷期：2009年48-37] Uronate isomerase (URI) catalyzes the reversible isomerization Of D-glucuronate to D-fructuronate and of D-galacturonate to D-tagaturonate. URI is a member of the amidohydrolase superfamily (AHS), a highly divergent grou... Mutagenesis and Evolution of Sulfated Antibodies Using an Expanded Genetic Code [作者：Liu, CC; Choe, H; Farzan, M; Smider, VV; Schultz, PG,期刊：Biochemistry, 页码：8891-8898 , 文章类型： Article，,卷期：2009年48-37] To facilitate the biochemical study of posttranslationally modified proteins, we have developed a strategy in which otherwise posttranslationally modified amino acids are genetically encoded in Escherichia coli in respon...