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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共28条记录   Purification and Characterization of the Lipid A Disaccharide Synthase (LpxB) from Escherichia coli, a Peripheral Membrane Protein [作者：Metzger, LE; Raetz, CRH,期刊：Biochemistry, 页码：11559-11571 , 文章类型： Article，,卷期：2009年48-48] Escherichia coli LpxB, an inverting glycosyl transferase of the GT-B superfamily and a member of CAZy database family 19, catalyzes the fifth step of lipid A biosynthesis: UDP-2,3-diacylglucosamine + 2, 3-diacylglucosami... The Structural Basis of Pregnane X Receptor Binding Promiscuity [作者：Ngan, CH; Beglov, D; Rudnitskaya, AN; Kozakov, D; Waxman, DJ; Vajda, S,期刊：Biochemistry, 页码：11572-11581 , 文章类型： Article，,卷期：2009年48-48] The steroid and xenobiotic-responsive human pregnane X receptor (PXR) binds a broad range of structurally diverse compounds. The structures of the apo and ligand-bound forms of PXR are very similar, ill contrast to most ... Mechanism of Fibril Formation by a 39-Residue Peptide (PAPf39) from Human Prostatic Acidic Phosphatase [作者：Ye, ZQ; French, KC; Popova, LA; Lednev, IK; Lopez, MM; Makhatadze, GI,期刊：Biochemistry, 页码：11582-11591 , 文章类型： Article，,卷期：2009年48-48] PAPf39 is a 39-residue peptide fragment from the sequence of human prostatic acidic phosphatase, This peptide was shown to form amyloid-like fibrils, which have been implicated in facilitating semen-mediated HIV transmis... Hepatitis C Virus NS3 Protease Is Activated by Low Concentrations of Protease Inhibitors [作者：Dahl, G; Arenas, OG; Danielson, UH,期刊：Biochemistry, 页码：11592-11602 , 文章类型： Article，,卷期：2009年48-48] The nonstructural protein 3 (NS3) of hepatitis C virus (HCV) is a bifunctional enzyme with a protease and a helicase functionality located in each of the two domains of the single peptide chain. There is little experimen... A Peptide Hairpin Inhibitor of Amyloid beta-Protein Oligomerization and Fibrillogenesis [作者：Yamin, G; Ruchala, P; Teplow, DB,期刊：Biochemistry, 页码：11329-11331 , 文章类型： Article，,卷期：2009年48-48] Amylold beta-protein (A beta) self-assembly is linked strongly to Alzheimer's disease. We found that PP-Leu, a tridecapeptide analogue of broad-spectrum antiviral peptides termed theta-defensins, potently inhibits A beta... Thermodynamic Aspects of Coupled Binding and Folding of an Intrinsically Disordered Protein: A Computational Alanine Scanning Study [作者：Espinoza-Fonseca, LM,期刊：Biochemistry, 页码：11332-11334 , 文章类型： Article，,卷期：2009年48-48] We have performed computational alanine scanning to gain insight into thermodynamic aspects of coupled Folding and binding of the phosphorylated kinase-inducible activation domain (pKID) of CREB, and intrinsically disord... Reversible Chemical Step and Rate-Limiting Enzyme Regeneration in the Reaction Catalyzed by Formamidopyrimidine-DNA Glycosylase [作者：Kuznetsov, NA; Zharkov, DO; Koval, VV; Buckle, M; Fedorova, OS,期刊：Biochemistry, 页码：11335-11343 , 文章类型： Article，,卷期：2009年48-48] Formamidopyrimidine-DNA N-glycosylase (Fpg) operates in the base excision repair pathway ill bacteria by removing oxidized guanine bases from DNA and can also cleave the nascent or preformed abasic DNA by P,beta,delta-el... Binding of Short Oligonucleotides to RNA: Studies of the Binding of Common RNA Structural Motifs to Isoenergetic Microarrays [作者：Kierzek, E,期刊：Biochemistry, 页码：11344-11356 , 文章类型： Article，,卷期：2009年48-48] Binding of short oligonucleotides to RNA is Important for many biological processes. On the basis of RNAi phenomena, antisense, and ribozyme approaches, it is useful in the inhibition of biological functions. To be consi... Kinetic Mechanism for the Flipping and Excision of 1,N-6-Ethenoadenine by Human Alkyladenine DNA Glycosylase [作者：Wolfe, AE; O'Brien, PJ,期刊：Biochemistry, 页码：11357-11369 , 文章类型： Article，,卷期：2009年48-48] Human alkyladenine DNA glycosylase initiates the repair of a wide variety of alkylated and deaminated purine lesions in DNA. In this study, we take advantage of the natural fluorescence of the 1,N-6-ethenoadenosine (epsi... The 8 and 5 kDa Fragments of Plasma Gelsolin Form Amyloid Fibrils by a Nucleated Polymerization Mechanism, while the 68 kDa Fragment Is Not Amyloidogenic [作者：Solomon, JP; Yonemoto, IT; Murray, AN; Price, JL; Powers, ET; Balch, WE; Kelly, JW,期刊：Biochemistry, 页码：11370-11380 , 文章类型： Article，,卷期：2009年48-48] Familial amyloidosis of Finnish type (FAF), or gelsolin amyloidosis, is a systemic amyloid disease caused by a mutation (D187N/-Y) in domain 2 of human plasma gelsolin, resulting in domain 2 misfolding within the secreto... Structural, Thermodynamic, and Kinetic Effects of a Phosphomimetic Mutation in Dynein Light Chain LC8 [作者：Benison, G; Chiodo, M; Karplus, PA; Barbar, E,期刊：Biochemistry, 页码：11381-11389 , 文章类型： Article，,卷期：2009年48-48] Dynein light chain LC8 is a small, dimeric, very highly conserved globular protein first identified as an integral part or the dynein and myosin molecular motors but now recognized as a dimerization hub with wider signif... Electron Transfer from Cytochrome c(2) to the Reaction Center: A Transition State Model for Ionic Strength Effects Due to Neutral Mutations [作者：Abresch, EC; Gong, XM; Paddock, ML; Okamura, MY,期刊：Biochemistry, 页码：11390-11398 , 文章类型： Article，,卷期：2009年48-48] Interprotein electron transfer plays an important role in biological energy conversion. In this work, the electron transfer reaction between cytochrome c(2) (cyt) and the reaction center (RC) was studied to determine the... Kinetic Stability of the Flavin Semiquinone in Photolyase and Cryptochrome-DASH [作者：Damiani, MJ; Yalloway, GN; Lu, J; McLeod, NR; O'Neill, MA,期刊：Biochemistry, 页码：11399-11411 , 文章类型： Article，,卷期：2009年48-48] Photolyases and cryptochromes (CRY) are structurally homologous flavoproteins with divergent functions. While photolyases repair UV-damaged DNA by photoinduced electron transfer from their FAD cofactor, CRY are involved ... Kinetic Characterization of Xenobiotic Reductase A from Pseudomonas putida 86 [作者：Spiegelhauer, O; Dickert, F; Mende, S; Niks, D; Hille, R; Ullmann, M; Dobbek, H,期刊：Biochemistry, 页码：11412-11420 , 文章类型： Article，,卷期：2009年48-48] Xenobiotic reductase A (XenA) from Pseudomonas putida is a member of the old-yellow-enzyme family of flavin-containing enzymes and catalyzes the NADH/NADPH-dependent reduction of various substrates, including 8-hydroxyco... Assembly with the Na,K-ATPase alpha(1) Subunit Is Required for Export of beta(1) and beta(2) Subunits from the Endoplasmic Reticulum [作者：Tokhtaeva, E; Sachs, G; Vagin, O,期刊：Biochemistry, 页码：11421-11431 , 文章类型： Article，,卷期：2009年48-48] The level of the heterodimeric Na,K-ATPase is tightly controlled in epithelia to maintain appropriate transport function. The catalytic Na,K-ATPase alpha subunit is not able to exit the ER or catalyze ion transport unles... Allosteric Interactions Direct Binding and Phosphorylation of ASF/SF2 by SRPK1 [作者：Huynh, N; Ma, CT; Giang, N; Hagopian, J; Ngo, J; Adams, J; Ghosh, G,期刊：Biochemistry, 页码：11432-11440 , 文章类型： Article，,卷期：2009年48-48] ASF/SF2, a member of the serine-arginine (SR) protein family, has two RRM domains (RRM1 and RRM2) and a C-terminal domain rich in RS dipeptides. SR protein kinase 1 (SRPK1) phosphorylates approximately 12 of these serine...