- Structural Control of Chemoselectivity, Stereoselectivity, and Substrate Specificity in Membrane-Bound Fatty Acid Acetylenases and Desaturases
[作者:Gagne, SJ; Reed, DW; Gray, GR; Covello, PS,期刊:Biochemistry, 页码:12298-12304 , 文章类型: Article,,卷期:2009年48-51]
- The FAD2-like desaturases comprise it group of membrane-bound oxygenases involved in the modification of fatty acyl groups In plants and fungi. This group includes typical oleate desaturases which introduce a Delta 12 ci...
- Mechanistic Studies of para-Substituted N,N '-Dibenzyl-1,4-diaminobutanes as Substrates for a Mammalian Polyamine Oxidase
[作者:Pozzi, MH; Gawandi, V; Fitzpatrick, PF,期刊:Biochemistry, 页码:12305-12313 , 文章类型: Article,,卷期:2009年48-51]
- The kinetics of oxidation of a series of para-substituted N,N'-dibenzyl-1,4-diaminobutanes by the flavoprotein polyamine oxidase from mouse have been determined to gain insight into the mechanism of airline oxidation by ...
- Disentangling the Web of Allosteric Communication in a Homotetramer: Heterotropic Inhibition in Phosphofructokinase from Escherichia coli
[作者:Fenton, AW; Reinhart, GD,期刊:Biochemistry, 页码:12323-12328 , 文章类型: Article,,卷期:2009年48-51]
- This Study quantifies the contribution of each of the four unique inhibiting heterotropic interactions between the allosteric inhibitor, phosphoenolpyruvate (PEP), and the Substrate, fructose 6-phosphate (Fru-6-P), in ph...
- Receptor and Subunit Specific Interactions of RIC-3 with Nicotinic Acetylcholine Receptors
[作者:Ben-Ami, HC; Biala, Y; Farah, H; Elishevitz, E; Battat, E; Treinin, M,期刊:Biochemistry, 页码:12329-12336 , 文章类型: Article,,卷期:2009年48-51]
- RIC-3 belongs to a conserved family of proteins influencing maturation of nicotinic acetylcholine receptors (nAChRs). RIC-3 homologues were shown to differently affect different nAChRs. Here we show that coexpression wit...
- Rapid and Reversible Inhibition of Aquaporin-4 by Zinc
[作者:Yukutake, Y; Hirano, Y; Suematsu, M; Yasui, M,期刊:Biochemistry, 页码:12059-12061 , 文章类型: Article,,卷期:2009年48-51]
- Aquaporin-4 (AQP4) is the predominant water channel in the brain. Although AQP4 plays an important role in brain water homeostasis, the molecular mechanisms of AQP4 regulation are not fully understood. In this report, We...
- Evidence of a Specific Interaction between New Synthetic Antisepsis Agents and CD14
[作者:Piazza, M; Yu, LP; Teghanemt, A; Gioannini, T; Weiss, J; Peri, F,期刊:Biochemistry, 页码:12337-12344 , 文章类型: Article,,卷期:2009年48-51]
- Synthetic molecules derived from natural sugars with a positively charged amino group or ammonium salt and two lipophilic chains have been shown to inhibit TLR4 activation In vitro and in vivo. To characterize the mechan...
- Disulfide-Dependent Self-Assembly of Adiponectin Octadecamers from Trimers and Presence of Stable Octadecameric Adiponectin Lacking Disulfide Bonds in Vitro
[作者:Briggs, DB; Jones, CM; Mashalidis, EH; Nunez, M; Hausrath, AC; Wysocki, VH; Tsao, TS,期刊:Biochemistry, 页码:12345-12357 , 文章类型: Article,,卷期:2009年48-51]
- Adiponectin is a circulating insulin-sensitizing hormone that homooligomerizes into trimers, hexamers, and higher molecular weight (HMW) species. Low levels Of circulating HMW adiponectin appear to increase the risk for ...
- Association of Phosphatidic Acid with the Bovine Mitochondrial ADP/ATP Carrier
[作者:Epand, RM; Epand, RF; Berno, B; Pelosi, L; Brandolin, G,期刊:Biochemistry, 页码:12358-12364 , 文章类型: Article,,卷期:2009年48-51]
- The beef heart adenine nucleotide carrier protein (Anc) of the inner mitochondrial membrane can be purified in a form stabilized by binding the inhibitor carboxyatractyloside, The protein is copurified with bound lipid. ...
- Ca2+ Channels on the Move
[作者:Taylor, CW; Prole, DL; Rahman, T,期刊:Biochemistry, 页码:12062-12080 , 文章类型: Review,,卷期:2009年48-51]
- The versatility of Ca2+ its an intracellular messenger derives largely from the spatial organization of cytosolic Ca2+ signals, most of which are generated by regulated openings of Ca2+-permeable channels. Most Ca2+ chan...
- Partially Folded Forms of Barley Lipid Transfer Protein Are More Surface Active
[作者:Mills, ENC; Gao, C; Wilde, PJ; Rigby, NM; Wijesinha-Bettoni, R; Johnson, VE; Smith, LJ; Mackie, AR,期刊:Biochemistry, 页码:12081-12088 , 文章类型: Article,,卷期:2009年48-51]
- Thermal and chemical modification of protein structures is known to affect their interfacial activity. We have looked in detail at the effect of heating on the structure and subsequently the surface properties of LTP1, a...
- Effect of Chloride Binding on the Thermal Trimer-Monomer Conversion of Halorhodopsin in the Solubilized System
[作者:Sasaki, T; Aizawa, T; Kamiya, M; Kikukawa, T; Kawano, K; Kamo, N; Demura, M,期刊:Biochemistry, 页码:12089-12095 , 文章类型: Article,,卷期:2009年48-51]
- Halorhodopsin from Natronomonas pharaonis (NpHR) acts an inward-directed, light-driven chloride pump and forms a homotrimer. To evaluate effect of trimeric assembly, that is, intermolecular interaction, on the control or...
- Communication between R481 and Cu-B in Cytochrome bo(3) Ubiquinol Oxidase from Escherichia coli
[作者:Egawa, T; Lin, MT; Hosler, JP; Gennis, RB; Yeh, SR; Rousseau, DL,期刊:Biochemistry, 页码:12113-12124 , 文章类型: Article,,卷期:2009年48-51]
- The R481 residue of cytochrome bo(3) ubiquinol oxidase from E. coli is highly conserved in the heme-copper oxidase superfamily. It has been postulated to serve as part of a proton loading site that regulates proton trans...
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