个性化文献订阅>文章检索

文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共11条记录   Antiproteinuric therapy decreases LDL-cholesterol as well as HDL-cholesterol in non-diabetic proteinuric patients: relationships with cholesteryl ester transfer protein mass and adiponectin [作者：Krikken, JA; Waanders, F; Dallinga-Thie, GM; Dikkeschei, LD; Vogt, L; Navis, GJ; Dullaart, RPF,期刊：Expert Opinion on Therapeutic Targets, 页码：497-504 , 文章类型： Article，,卷期：2009年13-5] Objective: Dyslipidemia contributes to increased cardiovascular risk in nephrotic syndrome. We questioned whether reduction in proteinuria not only lowers low-density lipoprotein cholesterol (LDL-C), but also high-densit... A critical role of COX-2 in the progression of neointimal formation after wire injury in mice [作者：Ogawa, M; Suzuki, J; Hirata, Y; Nagai, R; Isobe, M,期刊：Expert Opinion on Therapeutic Targets, 页码：505-511 , 文章类型： Article，,卷期：2009年13-5] Background: Inflammation plays an important role in neointimal hyperplasia after vascular injury. COX-2 is a key mediator of inflammation and contributes to several inflammatory diseases. Although selective COX-2 inhibit... Resolvin E1 as a novel agent for the treatment of asthma [作者：Hisada, T; Ishizuka, T; Aoki, H; Mori, M,期刊：Expert Opinion on Therapeutic Targets, 页码：513-522 , 文章类型： Review，,卷期：2009年13-5] Background: Asthma is characterized by airway hyperresponsiveness and chronic airway inflammation. Inflammatory cells, including eosinophils and lymphocytes, infiltrate peribronchial tissue in patients with asthma. Resol... ADAM8: a new therapeutic target for asthma [作者：Knolle, MD; Owen, CA,期刊：Expert Opinion on Therapeutic Targets, 页码：523-540 , 文章类型： Review，,卷期：2009年13-5] Background: A proteinase with a disintegrin and a metalloproteinase domain-8 (ADAM8) has been linked to asthma. Objective: To explore whether ADAM8 is a therapeutic target for asthma. Methods: We reviewed literature on A... Nephroprotective and clinical potential of statins in dialyzed patients [作者：Rysz, J; Aronow, WS; Stolarek, RS; Hannam, S; Mikhailidis, DP; Banach, M,期刊：Expert Opinion on Therapeutic Targets, 页码：541-550 , 文章类型： Review，,卷期：2009年13-5] Background: The combination of increased cardiovascular mortality and vascular complications due to dyslipidaemia in chronic kidney disease (CKD) has focused attention onto the potential beneficial effects of 3-hydroxy-3... Therapeutic targets for Alzheimer's disease [作者：Tarditi, A; Caricasole, A; Terstappen, GC,期刊：Expert Opinion on Therapeutic Targets, 页码：551-567 , 文章类型： Review，,卷期：2009年13-5] Background: Alzheimer's disease (AD), the most common form of degenerative dementia, represents a tremendous unmet medical need. Although AD had already been described about 100 years ago and despite enormous research ef... Inhibition of HGF/MET as therapy for malignancy [作者：Naran, S; Zhang, XL; Hughes, SJ,期刊：Expert Opinion on Therapeutic Targets, 页码：569-581 , 文章类型： Review，,卷期：2009年13-5] Background: Inhibition of inappropriate tyrosine kinase activity by neoplasms is an attractive strategy for the treatment of malignancy. Objective: We aimed to produce a concise review of the potential role of hepatocyte... Novel factors as therapeutic targets to treat diabetes. Focus on leptin and ghrelin [作者：Gomez, R; Lago, F; Gomez-Reino, JJ; Gualillo, O,期刊：Expert Opinion on Therapeutic Targets, 页码：583-591 , 文章类型： Review，,卷期：2009年13-5] Background: Obesity is the major cause of type 2 diabetes. In the mid 1990s interest in adipose tissue was revived by the discovery of leptin. The association of obesity and diabetes emphasizes their shared physiopatholo... Molecular switching of osteoblastogenesis versus adipogenesis: implications for targeted therapies [作者：Takada, I; Kouzmenko, AP; Kato, S,期刊：Expert Opinion on Therapeutic Targets, 页码：593-603 , 文章类型： Review，,卷期：2009年13-5] Osteoblasts and adipocytes differentiate from a common precursor, the pluripotent mesenchymal stem cell (MSC) found in bone marrow (BMSC) and adipose tissue (AD-MSC). Numerous transcription factors and multiple extracell... Targeting the proteasome pathway [作者：Tsukamoto, S; Yokosawa, H,期刊：Expert Opinion on Therapeutic Targets, 页码：605-621 , 文章类型： Review，,卷期：2009年13-5] Background: The ubiquitin-proteasome pathway functions as a main pathway in intracellular protein degradation and plays a vital role in almost all cellular events. Various inhibitors of this pathway have been developed f... Chronic beta-AR activation-induced calpain activation and impaired eNOS-Akt signaling mediates cardiac injury in ovariectomized female rats (vol 13, pg 275, 2009) [作者：Bhuyan, MS; Shioda, N; Fukuaga, K,期刊：Expert Opinion on Therapeutic Targets, 页码：623-623 , 文章类型： Correction，,卷期：2009年13-5]