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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共13条记录   A Review of Sodium Oxybate and Baclofen in the Treatment of Sleep Disorders [作者：Brown, MA; Guilleminault, C,期刊：Current Pharmaceutical Design, 页码：1430-1435 , 文章类型： Review，,卷期：2011年17-15] Studies examining GABAB receptor agonists have reported effects on sleep including decreased sleep onset latency (SOL), increased sleep consolidation and increases in slow wave sleep (SWS). gamma-hydroxybutyrate (GHB) is... Restless Legs Syndrome in Children: A Review and Update on Pharmacological Options [作者：Frenette, E,期刊：Current Pharmaceutical Design, 页码：1436-1442 , 文章类型： Review，,卷期：2011年17-15] Restless legs syndrome (RLS), formally identified and described by Ekbom in the 1940s, is a common clinical disorder, characterized by an overwhelming urge to move the legs, often accompanied by uncomfortable and unpleas... Opioids, Sleep, and Sleep-Disordered Breathing [作者：Zutler, M; Holty, JEC,期刊：Current Pharmaceutical Design, 页码：1443-1449 , 文章类型： Review，,卷期：2011年17-15] Opioid medications are increasingly used to treat chronic pain. Opioid-associated respiratory depression, and their potential to cause nocturnal apneas, is increasingly recognized as a major contributor to nocturnal hypo... Pharmacological Treatment of ADHD and the Short and Long Term Effects on Sleep [作者：Huang, YS; Tsai, MH; Guilleminault, C,期刊：Current Pharmaceutical Design, 页码：1450-1458 , 文章类型： Review，,卷期：2011年17-15] There is growing research focusing on the sleep problems of children with attention-deficit/hyperactivity disorder (ADHD) in recent years. High incidence of sleep disorders in children with ADHD may be associated with a ... Circadian Rhythms, Melatonin and Depression [作者：Salva, MAQ; Hartley, S; Barbot, F; Alvarez, JC; Lofaso, F; Guilleminault, C,期刊：Current Pharmaceutical Design, 页码：1459-1470 , 文章类型： Review，,卷期：2011年17-15] The master biological clock situated in the suprachiasmatic nuclei of the anterior hypothalamus plays a vital role in orchestrating the circadian rhythms of multiple biological processes. Increasing evidence points to a ... Pharmacological Advances in the Treatment of Insomnia [作者：Richey, SM; Krystal, AD,期刊：Current Pharmaceutical Design, 页码：1471-1475 , 文章类型： Review，,卷期：2011年17-15] Insomnia is a highly prevalent condition, and due to ongoing demand from patients suffering with this condition, new pharmacological treatments are actively being sought. As our neurophysiological understanding of insomn... Hypocretin Antagonists in Insomnia Treatment and Beyond [作者：Ruoff, C; Cao, M; Guilleminault, C,期刊：Current Pharmaceutical Design, 页码：1476-1482 , 文章类型： Review，,卷期：2011年17-15] Hypocretin neuropeptides have been shown to regulate transitions between wakefulness and sleep through stabilization of sleep promoting GABAergic and wake promoting cholinergic/monoaminergic neural pathways. Hypocretin a... The Ubiquitin-Proteasome System (UPS) and the Mechanism of Action of Bortezomib [作者：Cvek, B; Dvorak, Z,期刊：Current Pharmaceutical Design, 页码：1483-1499 , 文章类型： Review，,卷期：2011年17-15] Proteasome inhibition is a modern and surprisingly successful approach how to cancer treatment. Bortezomib(Velcade (R)) is a first-in-class proteasome inhibitor and has been approved for first-line treatment of multiple ... Evidence-based Medicine Update on Testosterone Replacement Therapy (TRT) in Male Hypogonadism: Focus on New Formulations [作者：Giagulli, VA; Triggiani, V; Corona, G; Carbone, D; Licchelli, B; Tafaro, E; Resta, F; Sabba, C; Maggi, M; Guastamacchia, E,期刊：Current Pharmaceutical Design, 页码：1500-1511 , 文章类型： Review，,卷期：2011年17-15] Until the 2000s Testosterone (T) Replacement Therapy (TRT) was not very satisfactory for male hypogonadic patients because the available T formulations were not able to reproduce the physiological pattern of T secretion ... Chronopharmaceuticals: Hype or Future of Pharmaceutics [作者：Philip, AK; Philip, B,期刊：Current Pharmaceutical Design, 页码：1512-1516 , 文章类型： Review，,卷期：2011年17-15] Drugs for several diseases are still given without regard to the time of the day. Variation in dosing time is generally related with the effectiveness and toxicity of many drugs. On the other hand, several drugs affect t... The Potential Role of Erythropoietin as a Pleiotropic Agent in Post-cardiac Arrest Syndrome [作者：Xanthos, T; Vasileiou, PVS; Kakavas, S; Syggelou, A; Iacovidou, N,期刊：Current Pharmaceutical Design, 页码：1517-1529 , 文章类型： Review，,卷期：2011年17-15] Sudden cardiac arrest is a leading cause of death worldwide with survival rates still remaining suboptimal. Unfortunately, most cardiac arrest patients, who achieve return of spontaneous circulation (ROSC), develop a mul... Untitled [作者：Cao, M,期刊：Current Pharmaceutical Design, 页码：1416-1417 , 文章类型： Editorial Material，,卷期：2011年17-15] Pharmacological Treatment of Obstructive Sleep Apnea [作者：Abad, VC; Guilleminault, C,期刊：Current Pharmaceutical Design, 页码：1418-1429 , 文章类型： Review，,卷期：2011年17-15] Obstructive sleep apnea (OSA) is a growing public health hazard fueled by the obesity epidemic and an aging population. Untreated sleep apnea can result in significant consequences both in the short-term and long-term. W...