- A Simple Code for Installing Hepatocyte Function
[作者：Willenbring, H,期刊：Cell Stem Cell, 页码：89-91 , 文章类型： Editorial Material，,卷期：2011年9-2]
- Forced lineage conversion of accessible cell types can supply scarce or inaccessible cells for research and therapy. Two papers in Nature now report the identification of transcription factors sufficient for inducing the...
- When BMP Meets FGF
[作者：Greber, B,期刊：Cell Stem Cell, 页码：91-92 , 文章类型： Editorial Material，,卷期：2011年9-2]
- Bone morphogenic proteins (BMPs) act as inducers of diverse cellular fates in human embryonic stem cells, but the mechanisms responsible remain poorly understood. In this issue of Cell Stem Cell, Bernardo et al. (2011) d...
- Gene Editing in Stem Cells Hits the Target
[作者：Kim, HW; Svendsen, CN,期刊：Cell Stem Cell, 页码：93-94 , 文章类型： Editorial Material，,卷期：2011年9-2]
- Two recent reports describe promising, highly efficient methods to modify genes in pluripotent stem cells using zinc finger nuclease (ZFN)-mediated (Soldner et al., 2011) or helper-dependent adenovirus (HDAdV)-mediated (...
- Inducing iPSCs to Escape the Dish
[作者：Barrilleaux, B; Knoepfler, PS,期刊：Cell Stem Cell, 页码：103-111 , 文章类型： Article，,卷期：2011年9-2]
- Induced pluripotent stem cells (iPSCs) hold great promise for autologous cell therapies, but significant roadblocks remain to translating iPSCs to the bedside. For example, concerns about the presumed autologous transpla...
- Direct Reprogramming of Adult Human Fibroblasts to Functional Neurons under Defined Conditions
[作者：Ambasudhan, R; Talantova, M; Coleman, R; Yuan, X; Zhu, SY; Lipton, SA; Ding, S,期刊：Cell Stem Cell, 页码：113-118 , 文章类型： Article，,卷期：2011年9-2]
- Human induced pluripotent stem cells (hiPSCs) have been generated by reprogramming a number of different somatic cell types using a variety of approaches. In addition, direct reprogramming of mature cells from one lineag...
- Ex Vivo Expanded Hematopoietic Stem Cells Overcome the MHC Barrier in Allogeneic Transplantation
[作者：Zheng, JK; Umikawa, M; Zhang, SC; Huynh, H; Silvany, R; Chen, BPC; Chen, LP; Zhang, CC,期刊：Cell Stem Cell, 页码：119-130 , 文章类型： Article，,卷期：2011年9-2]
- The lack of understanding of the interplay between hematopoietic stem cells (HSCs) and the immune system has severely hampered the stem cell research and practice of transplantation. Major problems for allogeneic transpl...
- Erythropoietin Preserves the Endothelial Differentiation Capacity of Cardiac Progenitor Cells and Reduces Heart Failure during Anticancer Therapies
[作者：Hoch, M; Fischer, P; Stapel, B; Missol-Kolka, E; Sekkali, B; Scherr, M; Favret, F; Braun, T; Eder, M; Schuster-Gossler, K; Gossler, A; Hilfiker, A; Balligand, JL; Drexler, H; Hilfiker-Kleiner, D,期刊：Cell Stem Cell, 页码：131-143 , 文章类型： Article，,卷期：2011年9-2]
- Anticancer therapies, such as targeting of STAT3 or the use of anthracyclins (doxorubicin), can induce cardiomyopathy. In mice prone to developing heart failure as a result of reduced cardiac STAT3 expression (cardiomyoc...
- BRACHYURY and CDX2 Mediate BMP-Induced Differentiation of Human and Mouse Pluripotent Stem Cells into Embryonic and Extraembryonic Lineages
[作者：Bernardo, AS; Faial, T; Gardner, L; Niakan, KK; Ortmann, D; Senner, CE; Callery, EM; Trotter, MW; Hemberger, M; Smith, JC; Bardwell, L; Moffett, A; Pedersen, RA,期刊：Cell Stem Cell, 页码：144-155 , 文章类型： Article，,卷期：2011年9-2]
- BMP is thought to induce hESC differentiation toward multiple lineages including mesoderm and trophoblast. The BMP-induced trophoblast phenotype is a long-standing paradox in stem cell biology. Here we readdressed BMP fu...
- Unexpected X Chromosome Skewing during Culture and Reprogramming of Human Somatic Cells Can Be Alleviated by Exogenous Telomerase
[作者：Pomp, O; Dreesen, O; Leong, DFM; Meller-Pomp, O; Tan, TT; Zhou, F; Colman, A,期刊：Cell Stem Cell, 页码：156-165 , 文章类型： Article，,卷期：2011年9-2]
- Somatic tissues in female eutherian mammals are mosaic due to random X inactivation. In contrast to mice, X chromosome reactivation does not occur during the reprogramming of human female somatic cells to induced pluripo...
- Tet1 Is Dispensable for Maintaining Pluripotency and Its Loss Is Compatible with Embryonic and Postnatal Development
[作者：Dawlaty, MM; Ganz, K; Powell, BE; Hu, YC; Markoulaki, S; Cheng, AW; Gao, Q; Kim, J; Choi, SW; Page, DC; Jaenisch, R,期刊：Cell Stem Cell, 页码：166-175 , 文章类型： Article，,卷期：2011年9-2]
- The Tet family of enzymes (Tet1/2/3) converts 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC). Mouse embryonic stem cells (mESCs) highly express Tet1 and have an elevated level of 5hmC. Tet1 has been implicated ...
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