- Hydraulic trade-offs and space filling enable better predictions of vascular structure and function in plants
[作者:Savage, VM; Bentley, LP; Enquist, BJ; Sperry, JS; Smith, DD; Reich, PB; von Allmen, EI,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:22722-22727 , 文章类型: Article,,卷期:2010年107-52]
- Plant vascular networks are central to botanical form, function, and diversity. Here, we develop a theory for plant network scaling that is based on optimal space filling by the vascular system along with trade-offs betw...
- Spatio-temporal sequence of cross-regulatory events in root meristem growth
[作者:Scacchi, E; Salinas, P; Gujas, B; Santuari, L; Krogan, N; Ragni, L; Berleth, T; Hardtke, CS,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:22734-22739 , 文章类型: Article,,卷期:2010年107-52]
- A central question in developmental biology is how multicellular organisms coordinate cell division and differentiation to determine organ size. In Arabidopsis roots, this balance is controlled by cytokinin-induced expre...
- Auxin transport through PIN-FORMED 3 (PIN3) controls shade avoidance and fitness during competition
[作者:Keuskamp, DH; Pollmann, S; Voesenek, LACJ; Peeters, AJM; Pierik, R,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:22740-22744 , 文章类型: Article,,卷期:2010年107-52]
- Plants grow in dense vegetations at the risk of being out-competed by neighbors. To increase their competitive power, plants display adaptive responses, such as rapid shoot elongation (shade avoidance) to consolidate lig...
- Follicle-stimulating hormone increases bone mass in female mice
[作者:Allan, CM; Kalak, R; Dunstan, CR; McTavish, KJ; Zhou, H; Handelsman, DJ; Seibel, MJ,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:22629-22634 , 文章类型: Article,,卷期:2010年107-52]
- Elevated follicle-stimulating hormone (FSH) activity is proposed to directly cause bone loss independent of estradiol deficiency in aging women. Using transgenic female mice expressing human FSH (TgFSH), we now reveal th...
- Crystal structure of the Epstein-Barr virus (EBV) glycoprotein H/glycoprotein L (gH/gL) complex
[作者:Matsuura, H; Kirschner, AN; Longnecker, R; Jardetzky, TS,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:22641-22646 , 文章类型: Article,,卷期:2010年107-52]
- The Epstein-Barr virus (EBV) is a gamma-herpesvirus that infects B cells and epithelial cells and that has been linked to malignancies in both cell types in vivo. EBV, like other herpesviruses, has three glycoproteins, g...
- Transfer of a prion strain to different hosts leads to emergence of strain variants
[作者:Mahal, SP; Browning, S; Li, JL; Suponitsky-Kroyter, I; Weissmann, C,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:22653-22658 , 文章类型: Article,,卷期:2010年107-52]
- Prions consist mainly of PrPSc, a pathogenic conformer of host-encoded PrPC. Prion populations with distinct phenotypes but associated with PrPSc, having the same amino acid sequence, constitute distinct strains. Strain ...
- FGF-1 induces ATP release from spinal astrocytes in culture and opens pannexin and connexin hemichannels
[作者:Garre, JM; Retamal, MA; Cassina, P; Barbeito, L; Bukauskas, FF; Saez, JC; Bennett, MVL; Abudara, V,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:22659-22664 , 文章类型: Article,,卷期:2010年107-52]
- Spinal astrocytes are coupled by connexin (Cx) gap junctions and express pannexin 1 (Px1) and purinergic receptors. Fibroblast growth factor 1 (FGF-1), which is released in spinal cord injury, activated spinal astrocytes...
- Thalamocortical model for a propofol-induced alpha-rhythm associated with loss of consciousness
[作者:Ching, SN; Cimenser, A; Purdon, PL; Brown, EN; Kopell, NJ,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:22665-22670 , 文章类型: Article,,卷期:2010年107-52]
- Recent data reveal that the general anesthetic propofol gives rise to a frontal alpha-rhythm at dose levels sufficient to induce loss of consciousness. In this work, a computational model is developed that suggests the n...
- Negative regulation of ciliary length by ciliary male germ cell-associated kinase (Mak) is required for retinal photoreceptor survival
[作者:Omori, Y; Chaya, T; Katoh, K; Kajimura, N; Sato, S; Muraoka, K; Ueno, S; Koyasu, T; Kondo, M; Furukawa, T,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:22671-22676 , 文章类型: Article,,卷期:2010年107-52]
- Cilia function as cell sensors in many organs, and their disorders are referred to as "ciliopathies." Although ciliary components and transport machinery have been well studied, regulatory mechanisms of ciliary formation...
- Longitudinal evidence for diminished frontal cortex function in aging
[作者:Nyberg, L; Salami, A; Andersson, M; Eriksson, J; Kalpouzos, G; Kauppi, K; Lind, J; Pudas, S; Persson, J; Nilsson, LG,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:22682-22686 , 文章类型: Article,,卷期:2010年107-52]
- Cross-sectional estimates of age-related changes in brain structure and function were compared with 6-y longitudinal estimates. The results indicated increased sensitivity of the longitudinal approach as well as qualitat...
- CBP gene transfer increases BDNF levels and ameliorates learning and memory deficits in a mouse model of Alzheimer's disease
[作者:Caccamo, A; Maldonado, MA; Bokov, AF; Majumder, S; Oddo, S,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:22687-22692 , 文章类型: Article,,卷期:2010年107-52]
- Cognitive dysfunction and memory loss are common features of Alzheimer's disease (AD). Abnormalities in the expression profile of immediate early genes that play a critical role in memory formation, such as the cAMP-resp...
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