Cancer gene therapy————————个性化文献订阅—

Suppression of tumor growth in xenograft model mice by programmed cell death 4 gene delivery using folate-PEG-baculovirus
[作者：Kim, YK; Kwon, JT; Choi, JY; Jiang, HL; Arote, R; Jere, D; Je, YH; Cho, MH; Cho, CS,期刊：Cancer gene therapy, 页码：751-760 , 文章类型： Article，,卷期：2010年17-11]
Cancer gene therapy using tumor suppressor genes is considered to be an attractive approach for arresting cell growth and inducing apoptosis. Programmed cell death 4 (Pdcd4) is a tumor suppressor gene, which prevents tum...

A fully replication-competent adenovirus vector with enhanced oncolytic properties
[作者：Toth, K; Kuppuswamy, M; Shashkova, E; Spencer, JF; Wold, WSM,期刊：Cancer gene therapy, 页码：761-770 , 文章类型： Article，,卷期：2010年17-11]
We have studied the oncolytic efficacy of two adenovirus vectors named KD3 and INGN 007, which differ from each other only in that whereas KD3 has two small deletions in its e1a gene that restrict its replication to rapi...

Recombinant adenovirus IL-24-Bax promotes apoptosis of hepatocellular carcinoma cells in vitro and in vivo
[作者：Li, J; Shi, L; Zhang, X; Kang, X; Wen, Y; Qian, H; Zhou, Y; Xu, W; Zhang, Y; Wu, M; Yin, Z,期刊：Cancer gene therapy, 页码：771-779 , 文章类型： Article，,卷期：2010年17-11]
Gene therapy promises to become an alternative choice for the treatment of hepatic cancer. In many cancers, the delivery of chimeric proteins by adenovirus vector has been reported to induce apoptosis. This study was ...

Enhanced target gene knockdown by a bifunctional shRNA: a novel approach of RNA interference
[作者：Rao, DD; Maples, PB; Senzer, N; Kumar, P; Wang, Z; Pappen, BO; Yu, Y; Haddock, C; Jay, C; Phadke, AP; Chen, S; Kuhn, J; Dylewski, D; Scott, S; Monsma, D; Webb, C; Tong, A; Shanahan, D; Nemunaitis, J,期刊：Cancer gene therapy, 页码：780-791 , 文章类型： Article，,卷期：2010年17-11]
RNA interference (RNAi) is a natural cellular regulatory process that inhibits gene expression by transcriptional, post-transcriptional and translational mechanisms. Synthetic approaches that emulate this process (small ...

Osteosarcoma cells as carriers to allow antitumor activity of canine oncolytic adenovirus in the presence of neutralizing antibodies
[作者：Alcayaga-Miranda, F; Cascallo, M; Rojas, JJ; Pastor, J; Alemany, R,期刊：Cancer gene therapy, 页码：792-802 , 文章类型： Article，,卷期：2010年17-11]
Osteosarcoma (OSA) is the most common bone tumor affecting the dog. The veterinary options for therapeutic management of OSA are limited and prognosis for such patients is poor. Oncolytic adenoviruses are attractive tool...

Combinatory cytotoxic effects produced by E1B-55kDa-deleted adenoviruses and chemotherapeutic agents are dependent on the agents in esophageal carcinoma
[作者：Ma, G; Kawamura, K; Li, Q; Okamoto, S; Suzuki, N; Kobayashi, H; Liang, M; Tada, Y; Tatsumi, K; Hiroshima, K; Shimada, H; Tagawa, M,期刊：Cancer gene therapy, 页码：803-813 , 文章类型： Article，,卷期：2010年17-11]
We examined possible combinatory antitumor effects of replication-competent type 5 adenoviruses (Ad) lacking E1B-55kDa molecules (Ad-delE1B55) and chemotherapeutic agents in nine human esophageal carcinoma cells. Ad-delE...

Ribozyme-mediated compensatory induction of menin-oncosuppressor function in primary fibroblasts from MEN1 patients
[作者：Luzi, E; Marini, F; Tognarini, I; Sala, SC; Galli, G; Falchetti, A; Brandi, ML,期刊：Cancer gene therapy, 页码：814-825 , 文章类型： Article，,卷期：2010年17-11]
Multiple endocrine neoplasia type 1 (MEN1) syndrome is characterized by the occurrence of tumors of parathyroids, neuroendocrine cells of the gastro-enteropancreatic tract and anterior pituitary. MEN1 gene encodes menin-...