- Adenovirus-mediated transfer of siRNA against survivin enhances the radiosensitivity of human non-small cell lung cancer cells
[作者:Yang, CT; Li, JM; Weng, HH; Li, YC; Chen, HC; Chen, MF,期刊:Cancer gene therapy, 页码:120-130 , 文章类型: Article,,卷期:2010年17-2]
- Expression of survivin has been reported to be correlated with shorter survival in patients with non-small cell lung cancer (NSCLC), and overexpression of survivin may lead to radioresistance in various human cancers. In...
- Downregulation of the coxsackie and adenovirus receptor in cancer cells by hypoxia depends on HIF-1 alpha
[作者:Kuster, K; Koschel, A; Rohwer, N; Fischer, A; Wiedenmann, B; Anders, M,期刊:Cancer gene therapy, 页码:141-146 , 文章类型: Article,,卷期:2010年17-2]
- Loss of the coxsackie and adenovirus receptor (CAR) has been found in various human cancers. Underlying mechanisms, however, are still poorly understood. Therefore, the objective of this study was to investigate the func...
- Oncolytic and immunostimulatory efficacy of a targeted oncolytic poxvirus expressing human GM-CSF following intravenous administration in a rabbit tumor model
[作者:Lee, JH; Roh, MS; Lee, YK; Kim, MK; Han, JY; Park, BH; Trown, P; Kirn, DH; Hwang, TH,期刊:Cancer gene therapy, 页码:73-79 , 文章类型: Article,,卷期:2010年17-2]
- Targeted oncolytic poxviruses hold promise for the treatment of cancer. Arming these agents with immunostimulatory cytokines (for example, granulocyte-monocyte colony-stimulating factor; GM-CSF) can potentially increase ...
- Inhibition of autophagy induced by overexpression of mda-7/interleukin-24 strongly augments the antileukemia activity in vitro and in vivo
[作者:Yang, C; Tong, Y; Ni, W; Liu, J; Xu, W; Li, L; Liu, X; Meng, H; Qian, W,期刊:Cancer gene therapy, 页码:109-119 , 文章类型: Article,,卷期:2010年17-2]
- Melanoma differentiation-associated gene-7/interleukin-24 (mda-7/IL-24) is a novel candidate of tumor suppressor that can selectively induce apoptosis experimentally in a spectrum of human cancer cells including leukemia...
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