- Advantages of bioluminescence imaging to follow siRNA or chemotherapeutic treatments in osteosarcoma preclinical models
[作者：Rousseau, J; Escriou, V; Perrot, P; Picarda, G; Charrier, C; Scherman, D; Heymann, D; Redini, F; Trichet, V,期刊：Cancer gene therapy, 页码：387-397 , 文章类型： Article，,卷期：2010年17-6]
- Osteosarcoma is the most common malignant primary bone tumor for which pertinent preclinical models are still needed to develop new therapeutic strategies. As osteosarcoma growth is strongly supported by bone resorption,...
- Role of anti-oncomirs miR-143 and-145 in human colorectal tumors
[作者：Akao, Y; Nakagawa, Y; Hirata, I; Iio, A; Itoh, T; Kojima, K; Nakashima, R; Kitade, Y; Naoe, T,期刊：Cancer gene therapy, 页码：398-408 , 文章类型： Article，,卷期：2010年17-6]
- We examined the expression levels of microRNAs (miRNAs (miRs)) in colorectal tumors ( 63 cancer specimens and 65 adenoma specimens) and paired non-tumorous tissues. Decreased expression of miR-143 and -145 was frequently...
- MicroRNAs targeting mutant K-ras by electrotransfer inhibit human colorectal adenocarcinoma cell growth in vitro and in vivo
[作者：Vidic, S; Markelc, B; Sersa, G; Coer, A; Kamensek, U; Tevz, G; Kranjc, S; Cemazar, M,期刊：Cancer gene therapy, 页码：409-419 , 文章类型： Article，,卷期：2010年17-6]
- Mutations of K-ras have been found in 30-60% of colorectal carcinomas and are believed to be associated with tumor initiation, tumor progression and metastasis formation. Therefore, silencing of mutant K-ras expression h...
- In vivo characterization of horseradish peroxidase with indole-3-acetic acid and 5-bromoindole-3-acetic acid for gene therapy of cancer
[作者：Tupper, J; Stratford, MR; Hill, S; Tozer, GM; Dachs, GU,期刊：Cancer gene therapy, 页码：420-428 , 文章类型： Article，,卷期：2010年17-6]
- Gene-directed enzyme prodrug therapy is a form of targeted cancer therapy, in which an enzyme is used to convert a non-toxic prodrug to a cytotoxin within the tumor. Horseradish peroxidase (HRP) is able to convert the in...
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