- Stress for Stress Tolerance? A Fundamentally New Approach in Mammalian Embryology
[作者:Pribenszky, C; Vajta, G; Molnar, M; Du, YT; Lin, L; Bolund, L; Yovich, J,期刊:Biology of Reproduction, 页码:690-697 , 文章类型: Review,,卷期:2010年83-5]
- In vitro culture, storage, and manipulation of gametes and embryos require meticulously adjusted conditions to avoid or minimize the harmful effects of uncontrolled stress. However, recent work indicates that a well-defi...
- Effect of Elevated Circulating Progesterone Concentration on Bovine Blastocyst Development and Global Transcriptome Following Endoscopic Transfer of In Vitro Produced Embryos to the Bovine Oviduct
[作者:Carter, F; Rings, F; Mamo, S; Holker, M; Kuzmany, A; Besenfelder, U; Havlicek, V; Mehta, JP; Tesfaye, D; Schellander, K; Lonergan, P,期刊:Biology of Reproduction, 页码:707-719 , 文章类型: Article,,卷期:2010年83-5]
- Elevated concentrations of circulating progesterone in the immediate postconception period have been associated with an increase in embryonic growth rate, interferon-tau production, and pregnancy rate in cattle and sheep...
- Histone Modifications at the Blastocyst Axin1(Fu) Locus Mark the Heritability of In Vitro Culture-Induced Epigenetic Alterations in Mice
[作者:Fernandez-Gonzalez, R; Ramirez, MA; Pericuesta, E; Calle, A; Gutierrez-Adan, A,期刊:Biology of Reproduction, 页码:720-727 , 文章类型: Article,,卷期:2010年83-5]
- For epigenetic phenotypes to be passed on from one generation to the next, it is required that epigenetic marks between generations are not cleared during the two stages of epigenetic reprogramming: mammalian gametogenes...
- Diverse Mechanisms of Endothelium-Derived Hyperpolarizing Factor-Mediated Dilatation in Small Myometrial Arteries in Normal Human Pregnancy and Preeclampsia
[作者:Luksha, L; Luksha, N; Kublickas, M; Nisell, H; Kublickiene, K,期刊:Biology of Reproduction, 页码:728-735 , 文章类型: Article,,卷期:2010年83-5]
- This ex vivo study focuses on the mechanisms of endothelium-dependent dilatation in the uterine circulation of normal pregnancy (n = 12) and in women with preeclampsia (n = 12). Arteries (internal diameter, similar to 25...
- Environmental Influence on Yolk Steroids in American Alligators (Alligator mississippiensis)
[作者:Hamlin, HJ; Lowers, RH; Albergotti, LC; Mccoy, MW; Mutz, J; Guillette, LJ,期刊:Biology of Reproduction, 页码:736-741 , 文章类型: Article,,卷期:2010年83-5]
- The egg yolk serves as a significant source of maternally derived steroids that are available to the embryo during early development. Altered deposition of yolk steroids can change the developmental trajectory of the emb...
- BMP4-Induced Differentiation of a Rat Spermatogonial Stem Cell Line Causes Changes in Its Cell Adhesion Properties
[作者:Carlomagno, G; van Bragt, MPA; Korver, CM; Repping, S; de Rooij, DG; van Pelt, AMM,期刊:Biology of Reproduction, 页码:742-749 , 文章类型: Article,,卷期:2010年83-5]
- Spermatogonial stem cells (SSCs) are at the basis of the spermatogenic process and are essential for the continuous lifelong production of spermatozoa. Although several factors that govern SSC self-renewal and differenti...
- Gene Expression Alterations by Conditional Knockout of Androgen Receptor in Adult Sertoli Cells of Utp14b(jsd/jsd) (jsd) Mice
[作者:Zhou, W; Wang, GS; Small, CL; Liu, ZL; Weng, CC; Yang, LZ; Griswold, MD; Meistrich, ML,期刊:Biology of Reproduction, 页码:759-766 , 文章类型: Article,,卷期:2010年83-5]
- Spermatogenesis is dependent primarily on testosterone action on the Sertoli cells, but the molecular mechanisms have not been identified. Attempts to identify testosterone-regulated target genes in Sertoli cells have us...
- Insulin-Like 3 Exposure of the Fetal Rat Gubernaculum Modulates Expression of Genes Involved in Neural Pathways
[作者:Johnson, KJ; Robbins, AK; Wang, YP; McCahan, SM; Chacko, JK; Barthold, JS,期刊:Biology of Reproduction, 页码:774-782 , 文章类型: Article,,卷期:2010年83-5]
- Insulin-like 3 (INSL3) signaling directs fetal gubernacular development and testis descent, but the actions of INSL3 in the gubernaculum are poorly understood. Using microarray gene expression profiling of fetal male rat...
- Retinoic Acid Availability Drives the Asynchronous Initiation of Spermatogonial Differentiation in the Mouse
[作者:Snyder, EM; Small, C; Griswold, MD,期刊:Biology of Reproduction, 页码:783-790 , 文章类型: Article,,卷期:2010年83-5]
- Throughout the reproductive lifespan of most male mammals, sperm production is constant because of the regulated differentiation of spermatogonia. Retinoic acid (RA) and a downstream target, Stra8, are required for compl...
- Transcriptional Profiling by Deep Sequencing Identifies Differences in mRNA Transcript Abundance in In Vivo-Derived Versus In Vitro-Cultured Porcine Blastocyst Stage Embryos
[作者:Bauer, BK; Isom, SC; Spate, LD; Whitworth, KM; Spollen, WG; Blake, SM; Springer, GK; Murphy, CN; Prather, RS,期刊:Biology of Reproduction, 页码:791-798 , 文章类型: Article,,卷期:2010年83-5]
- In vitro embryo culture systems promote development at rates lower than in vivo systems. The goal of this project was to discover transcripts that may be responsible for a decrease of embryo competency in blastocyst-stag...
- Ovine Surgical Model of Uterine Space Restriction: Interactive Effects of Uterine Anomalies and Multifetal Gestations on Fetal and Placental Growth
[作者:Meyer, KM; Koch, JM; Ramadoss, J; Kling, PJ; Magness, RR,期刊:Biology of Reproduction, 页码:799-806 , 文章类型: Article,,卷期:2010年83-5]
- Intrauterine growth restriction (IUGR) is observed in conditions with limitations in uterine space (e.g., uterine anomalies and multifetal gestations). IUGR is associated with reduced fetal weight, organ growth, and a sp...
- p-MAPK1/3 and DUSP6 Regulate Epididymal Cell Proliferation and Survival in a Region-Specific Manner in Mice
[作者:Xu, BF; Yang, L; Lye, RJ; Hinton, BT,期刊:Biology of Reproduction, 页码:807-817 , 文章类型: Article,,卷期:2010年83-5]
- A fully developed, functional epididymis is important for male fertility. In particular, it is apparent that without the most proximal region, the initial segment (IS), infertility results. Therefore, it is important to ...
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