个性化文献订阅>文章检索

文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共9条记录   The interaction of the von Hippel-Lindau tumor suppressor and heterochromatin protein 1 [作者：Lai, YL; Song, MH; Hakala, K; Weintraub, ST; Shiio, Y,期刊：Archives of Biochemistry and Biophysics , 页码：103-110 , 文章类型： Article，,卷期：2012年518-2] Inactivation of the von Hippel-Lindau (VHL) tumor suppressor is associated with renal carcinoma, hemangioblastoma and pheochromocytoma. The VHL protein is a component of a ubiquitin ligase complex that ubiquitinates and ... Binding to retinoblastoma pocket domain does not alter the inter-domain flexibility of the J domain of SV40 large T antigen [作者：Williams, CK; Vaithiyalingam, S; Hammel, M; Pipas, J; Chazin, WJ,期刊：Archives of Biochemistry and Biophysics , 页码：111-118 , 文章类型： Article，,卷期：2012年518-2] Simian Virus 40 uses the large T antigen (Tag) to bind and inactivate retinoblastoma tumor suppressor proteins (Rb), which can result in cellular transformation. Tag is a modular protein with four domains connected by fl... Features of the retinal environment which affect the activities and product profile of cholesterol-metabolizing cytochromes P450 CYP27A1 and CYP11A1 [作者：Heo, GY; Liao, WL; Turko, IV; Pikuleva, IA,期刊：Archives of Biochemistry and Biophysics , 页码：119-126 , 文章类型： Article，,卷期：2012年518-2] The retina is the sensory organ in the back of the eye which absorbs and converts light to electrochemical impulses transferred to the brain. Herein, we studied how retinal environment affects enzyme-mediated cholesterol... The role of Ile87 of CYP158A2 in oxidative coupling reaction [作者：Zhao, B; Bellamine, A; Lei, L; Waterman, MR,期刊：Archives of Biochemistry and Biophysics , 页码：127-132 , 文章类型： Article，,卷期：2012年518-2] Both CYP158A1 and CYP158A2 are able to catalyze an oxidative C-C coupling reaction producing biflaviolin or triflaviolin in Streptomyces coelicolor A3(2). The substrate-bound crystal structures of CYP158A2 and CYP158A1 r... Conditioned media from lung cancer cell line A549 and PC9 inactivate pulmonary fibroblasts by regulating protein phosphorylation [作者：Park, AM; Hayakawa, S; Honda, E; Mine, Y; Yoshida, K; Munakata, H,期刊：Archives of Biochemistry and Biophysics , 页码：133-141 , 文章类型： Article，,卷期：2012年518-2] Pulmonary fibrosis is a devastating condition resulting from excess extracellular matrix deposition that leads to progressive lung destruction and scarring. In the pathogenesis of fibrotic diseases, activation of myofibr... Urinary excretion of 8-oxo-7,8-dihydroguanine as biomarker of oxidative damage to DNA [作者：Loft, S; Danielsen, P; Lohr, M; Jantzen, K; Hemmingsen, JG; Roursgaard, M; Karotki, DG; Moller, P,期刊：Archives of Biochemistry and Biophysics , 页码：142-150 , 文章类型： Review，,卷期：2012年518-2] Oxidatively damaged DNA may be important in carcinogenesis. 8-0xo-7,8-dihydroguanine (8-oxoGua) is an abundant and mutagenic lesion excised by oxoguanine DNA glycosylase 1 (OGG1) and measurable in urine or plasma by chro... Cancer cell detection in tissue sections using AFM [作者：Lekka, M; Gil, D; Pogoda, K; Dulinska-Litewka, J; Jach, R; Gostek, J; Klymenko, O; Prauzner-Bechcicki, S; Stachura, Z; Wiltowska-Zuber, J; Okon, K; Laidler, P,期刊：Archives of Biochemistry and Biophysics , 页码：151-156 , 文章类型： Article，,卷期：2012年518-2] Currently, cancer diagnosis relies mostly on morphological examination of exfoliated, aspirated cells or surgically removed tissue. As long as standard diagnosis is concerned, this classical approach seems to be satisfac... Malate-aspartate shuttle and exogenous NADH/cytochrome c electron transport pathway as two independent cytosolic reducing equivalent transfer systems [作者：Abbrescia, DI; La Piana, G; Lofrumento, NE,期刊：Archives of Biochemistry and Biophysics , 页码：157-163 , 文章类型： Article，,卷期：2012年518-2] In mammalian cells aerobic oxidation of glucose requires reducing equivalents produced in glycolytic phase to be channelled into the phosphorylating respiratory chain for the reduction of molecular oxygen. Data never pre... Role of connexin 43 in the mechanism of action of alendronate: Dissociation of anti-apoptotic and proliferative signaling pathways [作者：Lezcano, V; Bellido, T; Plotkin, LI; Boland, R; Morelli, S,期刊：Archives of Biochemistry and Biophysics , 页码：95-102 , 文章类型： Article，,卷期：2012年518-2] Bisphosphonates (Bps) inhibit osteocyte and osteoblast apoptosis via opening of connexin (Cx) 43 hemichannels and activating the extracellular signal regulated kinases ERKs. Previously, we hypothesized that intracellular...