- Optimizing tacrolimus therapy in the maintenance of renal allografts: 12-month results
[作者:Bolin, P; Shihab, FS; Mulloy, L; Henning, AK; Gao, J; Bartucci, M; Holman, J; First, MR,期刊:Transplantation, 页码:88-95 , 文章类型: Article,,卷期:2008年86-1]
- Background. The determination of optimal tacrolimus (TAC) trough levels is needed to prevent adverse effects of calcineurin inhibitors.Methods. Stable transplant recipients currently receiving cyclosporine (CsA) were ass...
- Renal transplantation in patients with positive lymphocytotoxicity crossmatches: One center's experience
[作者:Magee, CC; Felgueiras, J; Tinckam, K; Malek, S; Mah, H; Tullius, S,期刊:Transplantation, 页码:96-103 , 文章类型: Article,,卷期:2008年86-1]
- Background. Sensitization to human leukocyte antigens remains an important barrier to successful renal transplantation.Materials and Methods. Herein we describe our center's experience with a plasmapheresis-based desensi...
- Chronic kidney disease - A common and serious complication after intestinal transplantation
[作者:Herlenius, G; Fagerlind, M; Krantz, M; Molne, J; Olausson, M; Gabel, M; Friman, V; Oltean, M; Friman, S,期刊:Transplantation, 页码:108-113 , 文章类型: Article,,卷期:2008年86-1]
- Background. Chronic kidney disease after organ transplantation is a serious complication that negatively impacts on long-term patient survival. We describe long-term renal function after intestinal transplantation by ser...
- Safe inclusion of the entire pancreas as a component of the multivisceral graft
[作者:Vianna, R; Fridell, JA; Mangus, R; Hollinger, EF; Matiosky, A; Tector, AJ,期刊:Transplantation, 页码:114-116 , 文章类型: Article,,卷期:2008年86-1]
- Background. Multivisceral transplantation (MVtx) involves simultaneous transplantation of the intestine with other organs, often including the pancreas. The pancreas portion of the graft has always been approached with c...
- Expanding the evidence base in transplantation: The complementary roles of randomized controlled trials and outcomes research
[作者:Takemoto, SK; Arns, W; Bunnapradist, S; Garrison, LP; Guirado, L; Kalo, Z; Oniscu, G; Opelz, G; Scolari, MP; Stefoni, S; Yaqoob, M; Brennan, DC,期刊:Transplantation, 页码:18-25 , 文章类型: Article,,卷期:2008年86-1]
- Transplantation offers a unique opportunity to demonstrate the complementary roles of randomized controlled trials and outcome research. The surgery and collaboration necessary for the transplant procedure makes randomiz...
- The use of exenatide in islet transplant recipients with chronic allograft dysfunction: Safety, efficacy, and metabolic effects
[作者:Froud, T; Faradji, RN; Pileggi, A; Messinger, S; Baidal, DA; Ponte, GM; Cure, PE; Monroy, K; Mendez, A; Selvaggi, G; Ricordi, C; Alejandro, R,期刊:Transplantation, 页码:36-45 , 文章类型: Article,,卷期:2008年86-1]
- Background. A current limitation of islet transplantation is reduced long-term graft function. The glucagon-like peptide-1 receptor agonist, exenatide (Byetta, Amylin Pharmaceuticals, CA) has proper-ties that could impro...
- Anti-proinflammatory effects of sirolimus on human islet preparations
[作者:Mita, A; Ricordi, C; Miki, A; Barker, S; Haertter, R; Hashikura, Y; Miyagawa, S; Burke, GW; Inverardi, L; Ichii, H,期刊:Transplantation, 页码:46-53 , 文章类型: Article,,卷期:2008年86-1]
- Background. Sirolimus plays a critical role in facilitating steroid-free immunosuppression, in conjunction with low dose tacrolimus, in current islet transplantation. Although several studies have investigated the effect...
- Pathology of an islet transplant 2 years after transplantation: Evidence for a nonimmunological loss
[作者:Smith, RN; Kent, SC; Nagle, J; Selig, M; Iafrate, AJ; Najafian, N; Hafler, DA; Auchincloss, H; Orban, T; Cagliero, E,期刊:Transplantation, 页码:54-62 , 文章类型: Article,,卷期:2008年86-1]
- Background. We report the immunological and pathological findings of a 52-year-old woman, who died two years after the second of two islet transplants performed using the Edmonton protocol. After each islet transplant, s...
- Randomized trial of mycophenolate mofetil versus enteric-coated mycophenolate sodium in primary renal transplant recipients given tacrolimus and daclizumab/thymoglobulin: One year follow-up
[作者:Ciancio, G; Burke, GW; Gaynor, JJ; Roth, D; Sageshima, J; Kupin, W; Tueros, L; Hanson, L; Rosen, A; Ruiz, P; Miller, J,期刊:Transplantation, 页码:67-74 , 文章类型: Article,,卷期:2008年86-1]
- Background. It was of interest to compare enteric-coated mycophenolate sodium (EC-MPS) versus mycophenolate mofetil (MMF) among renal transplant recipients receiving a tacrolimus-based immunosuppressive regimen.Methods. ...
- H-Y antibody development associates with acute rejection in female patients with male kidney transplants
[作者:Tan, JC; Wadia, PP; Coram, M; Grumet, FC; Kambham, N; Miller, K; Pereira, S; Vayntrub, T; Miklos, DB,期刊:Transplantation, 页码:75-81 , 文章类型: Article,,卷期:2008年86-1]
- Background. Human minor histocompatibility antigens (mHA) and clinically relevant immune responses to them have not been well defined in organ transplantation. We hypothesized that women with male kidney transplants woul...
- Fluvastatin in the prevention of renal transplant vasculopathy: Results of a prospective, randomized, double-blind, placebo-controlled trial
[作者:Seron, D; Oppenheimer, F; Pallardo, LM; Lauzurica, R; Errasti, P; Gomez-Huertas, E; Bosmans, LL; Sanchez-Plumed, J; Romero, R; Marques, M; Fulladosa, X; Moreso, F,期刊:Transplantation, 页码:82-87 , 文章类型: Article,,卷期:2008年86-1]
- Background. Statins prevent the progression of transplant vasculopathy in heart transplants, but its beneficial effect on the transplanted kidney is controversial.Methods. The aim is to evaluate the utility of fluvastati...
- Renal function impacts outcomes after intestinal transplantation
[作者:Watson, MJ; Venick, RS; Kaldas, F; Rastogi, A; Gordon, SA; Colangelo, J; Esmailian, Y; McDiarmid, SV; Busuttil, RW; Farmer, DG,期刊:Transplantation, 页码:117-122 , 文章类型: Article,,卷期:2008年86-1]
- Background. Although renal dysfunction (RD) has been commonly associated with poor outcome after other solid organ transplants, it has not been studied in detail after intestinal transplantation (ITx). Here we provide a ...
- C4d deposition and cellular infiltrates as markers of acute rejection in rat models of orthotopic lung transplantation
[作者:Murata, K; Iwata, T; Nakashima, S; Fox-Talbot, K; Qian, ZP; Wilkes, DS; Baldwin, WM,期刊:Transplantation, 页码:123-129 , 文章类型: Article,,卷期:2008年86-1]
- Background. C4d is a useful marker of antibody-mediated rejection in cardiac and renal transplants, but clinical studies examining correlations between circulating alloantibodies, C4d deposition, and rejection in lung tr...
- Contrasted blood and intragraft toll-like receptor 4 mRNA profiles in operational tolerance versus chronic rejection in kidney transplant recipients
[作者:Braudeau, C; Ashton-Chess, J; Giral, M; Dugast, E; Louis, S; Pallier, A; Braud, C; Moreau, A; Renaudin, K; Soulillou, JP; Brouard, S,期刊:Transplantation, 页码:130-136 , 文章类型: Article,,卷期:2008年86-1]
- Background. Deciphering the mechanisms of tolerance and chronic rejection (CR) remains a major goal in transplantation. Data in rodents suggest that Toll-like receptors (TLR), regulators of innate immune responses, play ...
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