- Development of novel CXCR4-based therapeutics
[作者:Peled, A; Wald, O; Burger, J,期刊:Expert opinion on investigational drugs, 页码:341-353 , 文章类型: Review,,卷期:2012年21-3]
- Introduction: During embryogenesis, CXCR4, a chemokine receptor, and its ligand, stromal cell-derived factor-1 (SDF-1/CXCL12), are critically involved in the development of the hematopoietic, nerve and endothelial tissue...
- Danusertib, an aurora kinase inhibitor
[作者:Meulenbeld, HJ; Mathijssen, RHJ; Verweij, J; de Wit, R; de Jonge, MJA,期刊:Expert opinion on investigational drugs, 页码:383-393 , 文章类型: Editorial Material,,卷期:2012年21-3]
- Introduction: Drugs that interfere with the normal progression of mitosis belong to the most successful cytotoxic agents currently used for anticancer treatment. Aurora kinases are serine/threonine kinases that function ...
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