- Identification of hydrophobic amino acids required for lipid activation of C. elegans CTP:phosphocholine cytidylyltransferase
[作者:Braker, JD; Hodel, KJ; Mullins, DR; Friesen, JA,期刊:Archives of Biochemistry and Biophysics , 页码:10-16 , 文章类型: Article,,卷期:2009年492-1-2]
- CTP:phosphocholine cytidylyltransferase (CCT), critical for phosphatidylcholine biosynthesis, is activated by translocation to the membrane Surface. The lipid activation region of Caenorhabditis elegans CCT is between re...
- Structural and biophysical properties of metal-free pathogenic SOD1 mutants A4V and G93A
[作者:Galaleldeen, A; Strange, RW; Whitson, LJ; Antonyuk, SV; Narayana, N; Taylor, AB; Schuermann, JP; Holloway, SP; Hasnain, SS; Hart, PJ,期刊:Archives of Biochemistry and Biophysics , 页码:40-47 , 文章类型: Article,,卷期:2009年492-1-2]
- Amyotrophic lateral sclerosis (ALS) is a fatal, progressive neurodegenerative disease characterized by the destruction of motor neurons in the spinal cord and brain. A subset of ALS cases are linked to dominant mutations...
- Sphingosine kinase 1 localized to the plasma membrane lipid raft microdomain overcomes serum deprivation induced growth inhibition
[作者:Hengst, JA; Guilford, JM; Fox, TE; Wang, XJ; Conroy, EJ; Yun, JK,期刊:Archives of Biochemistry and Biophysics , 页码:62-73 , 文章类型: Article,,卷期:2009年492-1-2]
- Several studies have demonstrated that sphingosine kinase 1 (SphK1) translocates to the plasma membrane (PM) upon its activation and further Suggested the plasma membrane lipid raft microdomain (PMLRM) as a target for Sp...
- Effect of high mobility group box-1 protein on apoptosis of peritoneal macrophages
[作者:Zhu, XM; Yao, YM; Liang, HP; Liu, F; Dong, N; Yu, Y; Sheng, ZY,期刊:Archives of Biochemistry and Biophysics , 页码:54-61 , 文章类型: Article,,卷期:2009年492-1-2]
The present study was performed to clarify the effects of high mobility group box-1 protein (HMGB1), a recently described late-acting pro-inflammatory cytokine, on apoptosis of macrophages. Treatment with HMGB1 (0.01,...
|