- NF-kappa B dictates the degradation pathway of I kappa B alpha (vol 27, pg 1357, 2008)
[作者：Mathes, E; O'Dea, EL; Hoffmann, A; Ghosh, G,期刊：EMBO journal, 页码：1421-1421 , 文章类型： Correction，,卷期：2008年27-9]
-
- Quantitative proliferation dynamics and random chromosome segregation of hair follicle stem cells
[作者：Waghmare, SK; Bansal, R; Lee, J; Zhang, YV; McDermitt, DJ; Tumbar, T,期刊：EMBO journal, 页码：1309-1320 , 文章类型： Article，,卷期：2008年27-9]
- Regulation of stem cell (SC) proliferation is central to tissue homoeostasis, injury repair, and cancer development. Accumulation of replication errors in SCs is limited by either infrequent division and/or by chromosome...
- Functioning of the dimeric GABA(B) receptor extracellular domain revealed by glycan wedge scanning
[作者：Rondard, P; Huang, S; Monnier, C; Tu, H; Blanchard, B; Oueslati, N; Malhaire, F; Li, Y; Trinquet, E; Labesse, G; Pin, JP; Liu, J,期刊：EMBO journal, 页码：1321-1332 , 文章类型： Article，,卷期：2008年27-9]
- The G-protein-coupled receptor (GPCR) activated by the neurotransmitter GABA is made up of two subunits, GABA(B1) and GABA(B2). GABA(B1) binds agonists, whereas GABA(B2) is required for trafficking GABA(B1) to the cell s...
- The kinase Syk as an adaptor controlling sustained calcium signalling and B-cell development
[作者：Kulathu, Y; Hobeika, E; Turchinovich, G; Reth, M,期刊：EMBO journal, 页码：1333-1344 , 文章类型： Article，,卷期：2008年27-9]
- Upon B-cell antigen receptor (BCR) activation, the protein tyrosine kinase Syk phosphorylates the adaptor protein SH2 domain-containing leukocyte protein of 65 kDa (SLP-65), thus coupling the BCR to diverse signalling pa...
- Activation of TRPP2 through mDia1-dependent voltage gating
[作者：Bai, CX; Kim, S; Li, WP; Streets, AJ; Ong, AC; Tsiokas, L,期刊：EMBO journal, 页码：1345-1356 , 文章类型： Article，,卷期：2008年27-9]
- The TRPP2 cation channel is directly responsible for similar to 15% of all cases of autosomal dominant polycystic kidney disease. However, the mechanisms underlying fundamental properties of TRPP2 regulation, such as cha...
- A synthetic lethal siRNA screen identifying genes mediating sensitivity to a PARP inhibitor
[作者：Turner, NC; Lord, CJ; Iorns, E; Brough, R; Swift, S; Elliott, R; Rayter, S; Tutt, AN; Ashworth, A,期刊：EMBO journal, 页码：1368-1377 , 文章类型： Article，,卷期：2008年27-9]
- Inhibitors of poly (ADP-ribose)-polymerase-1 (PARP) are highly lethal to cells with deficiencies in BRCA1, BRCA2 or other components of the homologous recombination pathway. This has led to PARP inhibitors entering clini...
- Mus81 is essential for sister chromatid recombination at broken replication forks
[作者：Roseaulin, L; Yamada, Y; Tsutsui, Y; Russell, P; Iwasaki, H; Arcangioli, B,期刊：EMBO journal, 页码：1378-1387 , 文章类型： Article，,卷期：2008年27-9]
- Recombination is essential for the recovery of stalled/collapsed replication forks and therefore for the maintenance of genomic stability. The situation becomes critical when the replication fork collides with an unrepai...
- Akt- and foxo1-interacting WD-repeat-FYVE protein promotes adipogenesis
[作者：Fritzius, T; Moelling, K,期刊：EMBO journal, 页码：1399-1410 , 文章类型： Article，,卷期：2008年27-9]
- We have previously identified a protein, consisting of seven WD-repeats, forming a putative beta-propeller, and an FYVE domain, ProF, which is highly expressed in 3T3-L1 cells, a cell line that can be differentiated into...
- Mechanism of intercellular molecular exchange in heterocyst-forming cyanobacteria
[作者：Mullineaux, CW; Mariscal, V; Nenninger, A; Khanum, H; Herrero, A; Flores, E; Adams, DG,期刊：EMBO journal, 页码：1299-1308 , 文章类型： Article，,卷期：2008年27-9]
- Heterocyst-forming filamentous cyanobacteria are true multicellular prokaryotes, in which heterocysts and vegetative cells have complementary metabolism and are mutually dependent. The mechanism for metabolite exchange b...
|