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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共10条记录   Yeast and human Ysl2p/hMon2 interact with Gga adaptors and mediate their subcellular distribution [作者：Singer-Kruger, B; Lasic, M; Burger, AM; Hausser, A; Pipkorn, R; Wang, Y,期刊：EMBO journal, 页码：1423-1435 , 文章类型： Article，,卷期：2008年27-10] The Gga proteins represent a family of ubiquitously expressed clathrin adaptors engaged in vesicle budding at the tubular endosomal network/trans Golgi network. Their membrane recruitment is commonly thought to involve i... Novel TCF-binding sites specify transcriptional repression by Wnt signalling [作者：Blauwkamp, TA; Chang, MV; Cadigan, KM,期刊：EMBO journal, 页码：1436-1446 , 文章类型： Article，,卷期：2008年27-10] Both transcriptional activation and repression have essential functions in maintaining proper spatial and temporal control of gene expression. Although Wnt signalling is often associated with gene activation, we have ide... Cooperative activity of cdk8 and GCN5L within Mediator directs tandem phosphoacetylation of histone H3 [作者：Meyer, KD; Donner, AJ; Knuesel, MT; York, AG; Espinosa, JM; Taatjes, DJ,期刊：EMBO journal, 页码：1447-1457 , 文章类型： Article，,卷期：2008年27-10] The human Mediator complex is generally required for expression of protein-coding genes. Here, we show that the GCN5L acetyltransferase stably associates with Mediator together with the TRRAP polypeptide. Yet, contrary t... Essential role of the chaperonin folding compartment in vivo [作者：Tang, YC; Chang, HC; Chakraborty, K; Hartl, FU; Hayer-Hartl, M,期刊：EMBO journal, 页码：1458-1468 , 文章类型： Article，,卷期：2008年27-10] The GroEL/GroES chaperonin system of Escherichia coli forms a nano-cage allowing single protein molecules to fold in isolation. However, as the chaperonin can also mediate folding independently of substrate encapsulation... Active remodelling of the TIM23 complex during translocation of preproteins into mitochondria [作者：Popov-Celeketic, D; Mapa, K; Neupert, W; Mokranjac, D,期刊：EMBO journal, 页码：1469-1480 , 文章类型： Article，,卷期：2008年27-10] The TIM23 (translocase of the mitochondrial inner membrane) complex mediates translocation of preproteins across and their insertion into the mitochondrial inner membrane. How the translocase mediates sorting of preprote... Hzf regulates adipogenesis through translational control of C/EBP alpha [作者：Kawagishi, H; Wakoh, T; Uno, H; Maruyama, M; Moriya, A; Morikawa, S; Okano, H; Sherr, CJ; Takagi, M; Sugimoto, M,期刊：EMBO journal, 页码：1481-1490 , 文章类型： Article，,卷期：2008年27-10] Adipocyte differentiation requires a well-defined programme of gene expression in which the transcription factor C/EBP alpha (CCAAT/enhancer-binding protein) has a central function. Here, we show that Hzf (haematopoietic... Oxygen-regulated degradation of fission yeast SREBP by Ofd1, a prolyl hydroxylase family member [作者：Hughes, BT; Espenshade, PJ,期刊：EMBO journal, 页码：1491-1501 , 文章类型： Article，,卷期：2008年27-10] Sre1, the fission yeast sterol regulatory element binding protein, is an endoplasmic reticulum membrane-bound transcription factor that responds to changes in oxygen-dependent sterol synthesis as an indirect measure of o... Histone methyltransferase Dot1 and Rad9 inhibit single-stranded DNA accumulation at DSBs and uncapped telomeres [作者：Lazzaro, F; Sapountzi, V; Granata, M; Pellicioli, A; Vaze, M; Haber, JE; Plevani, P; Lydall, D; Muzi-Falconi, M,期刊：EMBO journal, 页码：1502-1512 , 文章类型： Article，,卷期：2008年27-10] Cells respond to DNA double-strand breaks (DSBs) and uncapped telomeres by recruiting checkpoint and repair factors to the site of lesions. Single-stranded DNA (ssDNA) is an important intermediate in the repair of DSBs a... Topoisomerase III alpha is required for normal proliferation and telomere stability in alternative lengthening of telomeres [作者：Temime-Smaali, N; Guittat, L; Wenner, T; Bayart, E; Douarre, C; Gomez, D; Giraud-Panis, MJ; Londono-Vallejo, A; Gilson, E; Amor-Gueret, M; Riou, JF,期刊：EMBO journal, 页码：1513-1524 , 文章类型： Article，,卷期：2008年27-10] Topoisomerase (Topo) III alpha associates with BLM helicase, which is proposed to be important in the alternative lengthening of telomeres (ALT) pathway that allows telomere recombination in the absence of telomerase. He... Biological function in a non-native partially folded state of a protein [作者：Bemporad, F; Gsponer, J; Hopearuoho, HI; Plakoutsi, G; Stati, G; Stefani, M; Taddei, N; Vendruscolo, M; Chiti, F,期刊：EMBO journal, 页码：1525-1535 , 文章类型： Article，,卷期：2008年27-10] As structural flexibility is known to be required for enzyme catalysis and pattern recognition and a significant fraction of eukaryotic proteins appear to be unfolded or contain unstructured regions, biological activity ...