- The SpoMBe pathway drives membrane bending necessary for cytokinesis and spore formation in yeast meiosis
[作者：Maier, P; Rathfelder, N; Maeder, CI; Colombelli, J; Stelzer, EHK; Knop, M,期刊：EMBO journal, 页码：2363-2374 , 文章类型： Article，,卷期：2008年27-18]
- Precise control over organelle shapes is essential for cellular organization and morphogenesis. During yeast meiosis, prospore membranes (PSMs) constitute bell-shaped organelles that enwrap the postmeiotic nuclei leading...
- Distinct roles of RalA and RalB in the progression of cytokinesis are supported by distinct RalGEFs
[作者：Cascone, I; Selimoglu, R; Ozdemir, C; Del Nery, E; Yeaman, C; White, M; Camonis, J,期刊：EMBO journal, 页码：2375-2387 , 文章类型： Article，,卷期：2008年27-18]
- The Ras family G-proteins RalA and RalB make critical non-overlapping contributions to the generation of a tumorigenic regulatory network, supporting bypass of the normal restraints on both cell proliferation and surviva...
- A glial DEG/ENaC channel functions with neuronal channel DEG-1 to mediate specific sensory functions in C-elegans
[作者：Wang, Y; Apicella, A; Lee, SK; Ezcurra, M; Slone, RD; Goldmit, M; Schafer, WR; Shaham, S; Driscoll, M; Bianchi, L,期刊：EMBO journal, 页码：2388-2399 , 文章类型： Article，,卷期：2008年27-18]
- Mammalian neuronal DEG/ENaC channels known as ASICs (acid-sensing ion channels) mediate sensory perception and memory formation. ASICS are closed at rest and are gated by protons. Members of the DEG/ENaC family expressed...
- Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response
[作者：Morin, I; Ngo, HP; Greenall, A; Zubko, MK; Morrice, N; Lydall, D,期刊：EMBO journal, 页码：2400-2410 , 文章类型： Article，,卷期：2008年27-18]
- Exo1 is a nuclease involved in mismatch repair, DSB repair, stalled replication fork processing and in the DNA damage response triggered by dysfunctional telomeres. In budding yeast and mice, Exo1 creates single-stranded...
- Mutations of RNA polymerase II activate key genes of the nucleoside triphosphate biosynthetic pathways
[作者：Kwapisz, M; Wery, M; Despres, D; Ghavi-Helm, Y; Soutourina, J; Thuriaux, P; Lacroute, F,期刊：EMBO journal, 页码：2411-2421 , 文章类型： Article，,卷期：2008年27-18]
- The yeast URA2 gene, encoding the rate-limiting enzyme of UTP biosynthesis, is transcriptionally activated by UTP shortage. In contrast to other genes of the UTP pathway, this activation is not governed by the Ppr1 activ...
- SUMO modification of PCNA is controlled by DNA
[作者：Parker, JL; Bucceri, A; Davies, AA; Heidrich, K; Windecker, H; Ulrich, HD,期刊：EMBO journal, 页码：2422-2431 , 文章类型： Article，,卷期：2008年27-18]
- Post-translational modification by the ubiquitin-like protein SUMO is often regulated by cellular signals that restrict the modification to appropriate situations. Nevertheless, many SUMO-specific ligases do not exhibit ...
- Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila
[作者：Imai, Y; Gehrke, S; Wang, HQ; Takahashi, R; Hasegawa, K; Oota, E; Lu, BW,期刊：EMBO journal, 页码：2432-2443 , 文章类型： Article，,卷期：2008年27-18]
- Dominant mutations in leucine-rich repeat kinase 2 (LRRK2) are the most frequent molecular lesions so far found in Parkinson's disease (PD), an age-dependent neurodegenerative disorder affecting dopaminergic (DA) neuron....
- Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation
[作者：Guo, Z; Wu, YW; Das, D; Delon, C; Cramer, J; Yu, S; Thuns, S; Lupilova, N; Waldmann, H; Brunsveld, L; Goody, RS; Alexandrov, K; Blankenfeldt, W,期刊：EMBO journal, 页码：2444-2456 , 文章类型： Article，,卷期：2008年27-18]
- Post-translational isoprenylation of proteins is carried out by three related enzymes: farnesyltransferase, geranylgeranyl transferase-I, and Rab geranylgeranyl transferase (RabGGTase). Despite the fact that the last one...
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