- NADPH oxidase inhibitors: a patent review
[作者:Kim, JA; Neupane, GP; Lee, ES; Jeong, BS; Park, BC; Thapa, P,期刊:Expert Opinion on Therapeutic Patents, 页码:1147-1158 , 文章类型: Review,,卷期:2011年21-8]
- Introduction: NADPH oxidases, a family of multi-subunit enzyme complexes, catalyze the production of reactive oxygen species (ROS), which may contribute to the pathogenesis of a variety of diseases. In addition to the fi...
- New first and second generation inhibitors of human immunodeficiency virus-1 integrase
[作者:Pendri, A; Meanwell, NA; Peese, KM; Walker, MA,期刊:Expert Opinion on Therapeutic Patents, 页码:1173-1189 , 文章类型: Review,,卷期:2011年21-8]
- Introduction: The use of inhibitors of HIV-1 integrase for treating HIV-1 infection has proven to be very beneficial. Raltegravir, a strand transfer inhibitor, has been approved for use both as a first-line therapy and i...
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